Immunogenicity 1017

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
RADIL
Transcript ID
ENST00000445392
HLA INFO
DRB*15:02
TCR INFO

No TCR info found!

T cell Tumor cell DRB*15:02
sequence
Full length protein sequence (407 aa)
MFYGT
1
HFIMS
6
PPTKS
11
KLKRQ
16
SQLLS
21
SMLSR
26
TLSYK
31
YRDLD
36
STFSS
41
LGASD
46
DPAEL
51
STQLS
56
APGVL
61
KVFGD
66
SVCTG
71
THYKS
76
VLATG
81
TSSAR
86
ELVKE
91
ALERY
96
ALDPR
101
QAGQY
106
VLCDV
111
VGQAG
116
DAGQR
121
WQARC
126
FRVFG
131
DSEKP
136
LLIQE
141
LWKPR
146
EGLSR
151
RFELR
156
KRSDV
161
EELAA
166
KEVDT
171
ITAGI
176
NAQAR
181
RLQRS
186
RAKGT
191
PTPAL
196
GDARS
201
SPPPR
206
LRRTV
211
SETSL
216
SPVNA
221
LPAAA
226
QGPEE
231
PGPDA
236
MRYSL
241
YQSPH
246
LLLLQ
251
GYSQQ
256
HPGVC
261
AQPGP
266
AHGGP
271
ADPLQ
276
QAQHQ
281
PLSPR
286
HPAST
291
LHHPP
296
ATAPG
301
QRPGR
306
GEAGP
311
GAHPR
316
GAHLR
321
QLLRG
326
GAQDR
331
GAAPR
336
GPALP
341
GALLP
346
AAIQG
351
PRAGP
356
APARP
361
GLGAP
366
PGCAA
371
ELPAV
376
RGRAR
381
GPGSR
386
LPYSG
391
RPAPA
396
PAAAP
401
GV
406
Mutation Information
DNA mutation:
None
Peptide Range:
387 ~ 407
Mut AA position:
399 (13 in Wild Type peptide)
Alignment
Wild Type:
"PGSRLPYSGRPAPAPAAAPGV
||||||||||||.||||||||
Mutant:
PGSRLPYSGRPALAPAAAPGV"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ENSG00000157927

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay