Immunogenicity 103
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
ARAP2
Transcript ID
uc003gsr.1
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (1704 aa)
MSSVS
1
EVNVD
6
IKDFL
11
MSINL
16
EQYLL
21
HFHES
26
GFTTV
31
KDCAA
36
INDSL
41
LQKIG
46
ISPTG
51
HRRRI
56
LKQLQ
61
IILSK
66
MQDIP
71
IYANV
76
HKTKK
81
NDDPS
86
KDYHV
91
PSSDQ
96
NICIE
101
LSNSG
106
SVQTS
111
SPPQL
116
ETVRK
121
NLEDS
126
DASVE
131
RSQYP
136
QSDDK
141
LSPPK
146
RDFPT
151
AEEPH
156
LNLGS
161
LNDSL
166
FGSDN
171
IKIES
176
LITKK
181
TVDHT
186
VEEQQ
191
TEKVK
196
LITEN
201
LSKLP
206
NADSE
211
CLSFV
216
GCSTS
221
GTNSG
226
NGTNG
231
LLEGS
236
PPSPF
241
FKFQG
246
EMIVN
251
DLYVP
256
SSPIL
261
APVRS
266
RSKLV
271
SRPSR
276
SFLLR
281
HRPVP
286
EIPGS
291
TKGVS
296
GSYFR
301
ERRNV
306
ATSTE
311
KSVAW
316
QNSNE
321
ENSSS
326
IFPYG
331
ETFLF
336
QRLEN
341
SKKRS
346
IKNEF
351
LTQGE
356
ALKGE
361
AATAT
366
NSFII
371
KSSIY
376
DNRKE
381
KISED
386
KVEDI
391
WIPRE
396
DKNNF
401
LIDTA
406
SESEY
411
STVEE
416
CFQSL
421
RRKNS
426
KASKS
431
RTQKA
436
LILDS
441
VNRHS
446
YPLSS
451
TSGNA
456
DSSAV
461
SSQAI
466
SPYAC
471
FYGAS
476
AKKVK
481
SGWLD
486
KLSPQ
491
GKRMF
496
QKRWV
501
KFDGL
506
SISYY
511
NNEKE
516
MYSKG
521
IIPLS
526
AISTV
531
RVQGD
536
NKFEV
541
VTTQR
546
TFVFR
551
VEKEE
556
ERNDW
561
ISILL
566
NALKS
571
QSLTS
576
QSQAV
581
VTPEK
586
CGYLE
591
LRGYK
596
AKIFT
601
VLSGN
606
SVWLC
611
KNEQD
616
FKSGL
621
GITII
626
PMNVA
631
NVKQV
636
DRTVK
641
QSFEI
646
ITPYR
651
SFSFT
656
AETEK
661
EKQDW
666
IEAVQ
671
QSIAE
676
TLSDY
681
EVAEK
686
IWFNE
691
SNRSC
696
ADCKA
701
PDPDW
706
ASINL
711
CVVIC
716
KKCAG
721
QHRSL
726
GPKDS
731
KVRSL
736
KMDAS
741
IWSNE
746
LIELF
751
IVIGN
756
KRAND
761
FWAGN
766
LQKDE
771
ELHMD
776
SPVEK
781
RKNFI
786
TQKYK
791
EGKFR
796
KTLLA
801
SLTKE
806
ELNKA
811
LCAAV
816
VKPDV
821
LETMA
826
LLFSG
831
ADVMC
836
ATGDP
841
VHSTP
846
YLLAK
851
KAGQS
856
LQMEF
861
LYHNK
866
FSDFP
871
QHDIH
876
SEGVL
881
SQESS
886
QSTFL
891
CDFLY
896
QAPSA
901
ASKLS
906
SEKKL
911
LEETN
916
KKWCV
921
LEGGF
926
LSYYE
931
NDKST
936
TPNGT
941
ININE
946
VICLA
951
IHKED
956
FYLNT
961
GPIFI
966
FEIYL
971
PSERV
976
FLFGA
981
ETSQA
986
QRKWT
991
EAIAK
996
HFVPL
1001
FAENL
1006
TEADY
1011
DLIGQ
1016
LFYKD
1021
CHALD
1026
QWRKG
1031
WFAMD
1036
KSSLH
1041
FCLQM
1046
QEVQG
1051
DRMHL
1056
RRLQE
1061
LTIST
1066
MVQNG
1071
EKLDV
1076
LLLVE
1081
KGRTL
1086
YIHGH
1091
TKLDF
1096
TVWHT
1101
AIEKA
1106
AGTDG
1111
NALQD
1116
QQLSK
1121
NDVPI
1126
IVNSC
1131
IAFVT
1136
QYGLG
1141
CKYIY
1146
QKNGD
1151
PLHIS
1156
ELLES
1161
FKKDA
1166
RSFKL
1171
RAGKH
1176
QLEDV
1181
TAVLK
1186
SFLSD
1191
IDDAL
1196
LTKEL
1201
YPYWI
1206
SALDT
1211
QDDKE
1216
RIKKY
1221
GAFIR
1226
SLPGV
1231
NRATL
1236
AAIIE
1241
HLYRV
1246
QKCSE
1251
INHMN
1256
AHNLA
1261
LVFSS
1266
CLFQT
1271
KGQTS
1276
EEVNV
1281
IEDLI
1286
NNYVE
1291
IFEVK
1296
EDQVK
1301
QMDIE
1306
NSFIT
1311
KWKDT
1316
QVSQA
1321
GDLLI
1326
EVYVE
1331
RKEPD
1336
CSIII
1341
RISPV
1346
MEAEE
1351
LTNDI
1356
LAIKN
1361
IIPTK
1366
GDIWA
1371
TFEVI
1376
ENEEL
1381
ERPLH
1386
YKENV
1391
LEQVL
1396
RWSSL
1401
AEPGS
1406
AYLVV
1411
KRFLT
1416
ADTIK
1421
HCSDR
1426
STLGS
1431
IKEGI
1436
LKIKE
1441
EPSKI
1446
LSGNK
1451
FQDRY
1456
FVLRD
1461
GFLFL
1466
YKDVK
1471
SSKHD
1476
KMFSL
1481
SSMKF
1486
YRGVK
1491
KKMKP
1496
PTSWG
1501
LTAYS
1506
EKHHW
1511
HLCCD
1516
SSRTQ
1521
TEWMT
1526
SIFIA
1531
QHEYD
1536
IWPPA
1541
GKERK
1546
RSITK
1551
NPKIG
1556
GLPLI
1561
PIQHE
1566
GNATL
1571
ARKNI
1576
ESARA
1581
ELERL
1586
RLSEK
1591
CDKES
1596
VDSSL
1601
KERAS
1606
MVAHC
1611
LEHKD
1616
DKLRN
1621
RPRKH
1626
RSFNC
1631
LEDTE
1636
PEAPL
1641
GQPKG
1646
HKGLK
1651
TLRKT
1656
EDRNS
1661
KATLD
1666
SDHKL
1671
PSRVI
1676
EELNV
1681
VLQRS
1686
RTLPK
1691
ELQDE
1696
QILK
1701
Mutation Information
DNA mutation:
c.C2097A
Peptide Range:
687 ~ 711
Mut AA position:
699 (13 in Wild Type peptide)
Alignment
Wild Type:
"VAEKIWFNESNRSCADCKAPDPDWA
||||||||||||.||||||||||||
Mutant:
VAEKIWFNESNRRCADCKAPDPDWA"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) ARAP2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
VAEKIWFNESNRRCADCKAPDPDWA
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT