Immunogenicity 10306

summary
Sample ID
3812
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
PGR
Transcript ID
ENST00000263463
HLA INFO
DQA*01:03 / DQB*02:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*02:02
sequence
Full length protein sequence (831 aa)
MTELK
1
AKGPR
6
APHVA
11
GGPPS
16
PEVGS
21
PLLCR
26
PAAGP
31
FPGSQ
36
TSDTL
41
PEVSA
46
IPISL
51
DGLLF
56
PRPCQ
61
GQDPS
66
DEKTQ
71
DQQSL
76
SDVEG
81
AYSRA
86
EATRG
91
AGGSS
96
SSPPE
101
KDSGL
106
LDSVL
111
DTLLA
116
PSGPG
121
QSQPS
126
PPACE
131
VTSSW
136
CLFGP
141
ELPED
146
PPAAP
151
ATQRV
156
LSPLM
161
SRSGC
166
KVGDS
171
SGTAA
176
AHKVL
181
PRGLS
186
PARQL
191
LLPAS
196
ESPHW
201
SGAPV
206
KPSPQ
211
AAAVE
216
VEEED
221
GSESE
226
ESAGP
231
LLKGK
236
PRALG
241
GAAAG
246
GGAAA
251
VPPGA
256
AAGGV
261
ALVPK
266
EDSRF
271
SAPRV
276
ALVEQ
281
DAPMA
286
PGRSP
291
LATTV
296
MDFIH
301
VPILP
306
LNHAL
311
LAART
316
RQLLE
321
DESYD
326
GGAGA
331
ASAFA
336
PPRSS
341
PCASS
346
TPVAV
351
GDFPD
356
CAYPP
361
DAEPK
366
DDAYP
371
LYSDF
376
QPPAL
381
KIKEE
386
EEGAE
391
ASARS
396
PRSYL
401
VAGAN
406
PAAFP
411
DFPLG
416
PPPPL
421
PPRAT
426
PSRPG
431
EAAVT
436
AAPAS
441
ASVSS
446
ASSSG
451
STLEC
456
ILYKA
461
EGAPP
466
QQGPF
471
APPPC
476
KAPGA
481
SGCLL
486
PRDGL
491
PSTSA
496
SAAAA
501
GAAPA
506
LYPAL
511
GLNGL
516
PQLGY
521
QAAVL
526
KEGLP
531
QVYPP
536
YLNYL
541
RPDSE
546
ASQSP
551
QYSFE
556
SLPQK
561
ICLIC
566
GDEAS
571
GCHYG
576
VLTCG
581
SCKVF
586
FKRAM
591
EGQHN
596
YLCAG
601
RNDCI
606
VDKIR
611
RKNCP
616
ACRLR
621
KCCQA
626
GMVLG
631
GFRNL
636
HIDDQ
641
ITLIQ
646
YSWMS
651
LMVFG
656
LGWRS
661
YKHVS
666
GQMLY
671
FAPDL
676
ILNEQ
681
RMKES
686
SFYSL
691
CLTMW
696
QIPQE
701
FVKLQ
706
VSQEE
711
FLCMK
716
VLLLL
721
NTIPL
726
EGLRS
731
QTQFE
736
EMRSS
741
YIREL
746
IKAIG
751
LRQKG
756
VVSSS
761
QRFYQ
766
LTKLL
771
DNLHD
776
LVKQL
781
HLYCL
786
NTFIQ
791
SRALS
796
VEFPE
801
MMSEV
806
IAAQL
811
PKILA
816
GMVKP
821
LLFHK
826
K
831
Mutation Information
DNA mutation:
None
Peptide Range:
486 ~ 510
Mut AA position:
498 (13 in Wild Type peptide)
Alignment
Wild Type:
"SGCLLPRDGLPSTSASAAAAGAAPA
||||||||||||.||||||||||||
Mutant:
SGCLLPRDGLPSISASAAAAGAAPA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PGR

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

None

Assay

IFNg ELISPOT assay