Immunogenicity 1035

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
UTF1
Transcript ID
ENST00000304477
HLA INFO
C*01:02
TCR INFO

No TCR info found!

T cell Tumor cell C*01:02
sequence
Full length protein sequence (341 aa)
MLLRP
1
RRPPP
6
LAPPA
11
PPSPA
16
SPDPE
21
PRTPG
26
DAPGT
31
PPRRP
36
ASPSA
41
LGELG
46
LPVSP
51
GSAQR
56
TPWSA
61
RETEL
66
LLGTL
71
LQPAV
76
WRALL
81
LDRRQ
86
ALPTY
91
RRVSA
96
ALAQQ
101
QVRRT
106
PAQCR
111
RRYKF
116
LKDKF
121
REAHG
126
QPPGP
131
FDEQI
136
RKLMG
141
LLGDN
146
GRKRP
151
RRRSP
156
GSGRP
161
QRARR
166
PVPNA
171
HAPAP
176
SEPDA
181
TPLPT
186
ARDRD
191
ADPTW
196
TLRFS
201
PSPPK
206
SADAS
211
PAPGS
216
PPAPA
221
PTALA
226
TCIPE
231
DRAPV
236
RGPGS
241
PPPPP
246
AREDP
251
DSPPG
256
RPEDC
261
APPPA
266
APPSL
271
NTALL
276
QTLGH
281
LGDIA
286
NILGP
291
LRDQL
296
LTLNQ
301
HVEQL
306
RGAFD
311
QTVSL
316
AVGFI
321
LGSAA
326
AERGV
331
LRDPC
336
Q
341
Mutation Information
DNA mutation:
None
Peptide Range:
295 ~ 319
Mut AA position:
307 (13 in Wild Type peptide)
Alignment
Wild Type:
"PLRDQLLTLNQHVEQLRGAFDQTVS
||||||||||||.||||||||||||
Mutant:
PLRDQLLTLNQHMEQLRGAFDQTVS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) UTF1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay