Immunogenicity 10413

summary
Sample ID
3812
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
TUBA1A
Transcript ID
uc021qxn.1
HLA INFO
DQA*02:01 / DQB*06:03
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*02:01 DQB*06:03
sequence
Full length protein sequence (249 aa)
MVDNE
1
AIYDI
6
CRRNL
11
DIERP
16
TYTNL
21
NRLIS
26
QIVSS
31
ITASL
36
RFDGA
41
LNVDL
46
TEFQT
51
NLVPY
56
PRIHF
61
PLATY
66
APVIS
71
AEKAY
76
HEQLS
81
VAEIT
86
NACFE
91
PANQM
96
VKCDP
101
RHGKY
106
MACCL
111
LYRGD
116
VVPKD
121
VNAAI
126
ATIKT
131
KRSIQ
136
FVDWC
141
PTGFK
146
VGINY
151
QPPTV
156
VPGGD
161
LAKVQ
166
RAVCM
171
LSNTT
176
AIAEA
181
WARLD
186
HKFDL
191
MYAKR
196
AFVHW
201
YVGEG
206
MEEGE
211
FSEAR
216
EDMAA
221
LEKDY
226
EEVGV
231
DSVEG
236
EGEEE
241
GEEY
246
Mutation Information
DNA mutation:
None
Peptide Range:
48 ~ 72
Mut AA position:
60 (13 in Wild Type peptide)
Alignment
Wild Type:
"VDLTEFQTNLVPYPRIHFPLATYAP
||||||||||||.||||||||||||
Mutant:
VDLTEFQTNLVPHPRIHFPLATYAP"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) TUBA1A

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

None

Assay

IFNg ELISPOT assay