Immunogenicity 1042

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
SCML4
Transcript ID
ENST00000369025
HLA INFO
DQA*02:01 / DQB*02:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*02:01 DQB*02:02
sequence
Full length protein sequence (172 aa)
MNRYS
1
VDTSA
6
STFNH
11
RGSLH
16
PSSSL
21
YCKRQ
26
NSGDS
31
HLGGG
36
PAATA
41
GGPRT
46
SPMSS
51
GGPSA
56
PGLRP
61
PASSP
66
KRNTT
71
SLEGN
76
RCASS
81
PSQDA
86
QDARR
91
PRSRN
96
PSAWT
101
VEDVV
106
WFVKD
111
ADPQA
116
LGPHV
121
ELFRK
126
HEIDG
131
NALLL
136
LKSDM
141
VMKYL
146
GLKLG
151
PALKL
156
CYHID
161
KLKQA
166
KF
171
Mutation Information
DNA mutation:
None
Peptide Range:
100 ~ 124
Mut AA position:
112 (13 in Wild Type peptide)
Alignment
Wild Type:
"NPSAWTVEDVVWFVKDADPQALGPH
||||||||||||.||||||||||||
Mutant:
NPSAWTVEDVVWLVKDADPQALGPH"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SCML4

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay