Immunogenicity 10468

summary
Sample ID
3812
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
FSTL5
Transcript ID
uc010iqv.4
HLA INFO
DQA*01:03 / DQB*02:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*02:02
sequence
Full length protein sequence (837 aa)
MFKCW
1
SVVLV
6
LGFIF
11
LESEG
16
RPTKE
21
GGYGL
26
KSYQP
31
LMRLR
36
HKEKN
41
QESSR
46
VKGFM
51
IQDGP
56
FGSCE
61
NKYCG
66
LGRHC
71
VTSRE
76
TGQAE
81
CACMD
86
LCKRH
91
YKPVC
96
GSDGE
101
FYENH
106
CEVHR
111
AACLK
116
KQKIT
121
IVHNE
126
DCFFK
131
GDKCK
136
TTEYS
141
KMKNM
146
LLDLQ
151
NQKYI
156
MQENE
161
NPNGD
166
DISRK
171
KLLVD
176
QMFKY
181
FDADS
186
NGLVD
191
INELT
196
QVIKQ
201
EELGK
206
DLFDC
211
TLYVL
216
LKYDD
221
FNADK
226
HLALE
231
EFYRA
236
FQVIQ
241
LSLPE
246
DQKLS
251
ITAAT
256
VGQSA
261
VLSCA
266
IQGTL
271
RPPII
276
WKRNN
281
IILNN
286
LDLED
291
INDFG
296
DDGSL
301
YITKV
306
TTTHV
311
GNYTC
316
YADGY
321
EQVYQ
326
THIFQ
331
VNVPP
336
VIRVY
341
PESQA
346
REPGV
351
TASLR
356
CHAEG
361
IPKPQ
366
LGWLK
371
NGIDI
376
TPKLS
381
KQLTL
386
QANGS
391
EVHIS
396
NVRYE
401
DTGAY
406
TCIAK
411
NEAGV
416
DEDIS
421
SLFVE
426
DSARK
431
TRLGI
436
GNMFY
441
VFYED
446
GIKVI
451
QPIEC
456
EFQRH
461
IKPSE
466
KLLGF
471
QDEVC
476
PKAEG
481
DEVQR
486
CVWAS
491
AVNVK
496
DKFIY
501
VAQPT
506
LDRVL
511
IVDVQ
516
SQKVV
521
QAVST
526
DPVPV
531
KLHYD
536
KSHDQ
541
VWVLS
546
WGTLE
551
KTSPT
556
LQVIT
561
LASGN
566
VPHHT
571
IHTQP
576
VGKQF
581
DRVDD
586
FFIPT
591
TTLII
596
THMRF
601
GFILH
606
KDEAA
611
LQKID
616
LETMS
621
YIKTI
626
NLKDY
631
KCVPQ
636
SLAYT
641
HLGGY
646
YFIGC
651
KPDST
656
GAVSP
661
QVMVD
666
GVTDS
671
VIGFN
676
SDVTG
681
TPYVS
686
PDGHY
691
LVSIN
696
DVKGL
701
VRVQY
706
ITIRG
711
EIQEA
716
FDIYT
721
NLHIS
726
DLAFQ
731
PSFTE
736
AHQYN
741
IYGSS
746
STQTD
751
VLFVE
756
LSSGK
761
VKMIK
766
SLKEP
771
LKAEE
776
WPWNR
781
KNRQI
786
QDSGL
791
FGQYL
796
MTPSK
801
DSLFI
806
LDGRL
811
NKLNC
816
EITEV
821
EKGNT
826
VIWVG
831
DA
836
Mutation Information
DNA mutation:
None
Peptide Range:
609 ~ 633
Mut AA position:
621 (13 in Wild Type peptide)
Alignment
Wild Type:
"LHKDEAALQKIDLETMSYIKTINLK
||||||||||||.||||||||||||
Mutant:
LHKDEAALQKIDFETMSYIKTINLK"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) FSTL5

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

None

Assay

IFNg ELISPOT assay