Immunogenicity 10544

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
KCP
Transcript ID
uc011kos.1
HLA INFO
B*38:01
TCR INFO

No TCR info found!

T cell Tumor cell B*38:01
sequence
Full length protein sequence (814 aa)
MAGVG
1
AAALS
6
LLLHL
11
GALAL
16
AAGAE
21
GGAVP
26
REPPG
31
QQTTA
36
HSSVL
41
AGNSQ
46
EQWHP
51
LREWL
56
GRLEA
61
AVMEL
66
REQNK
71
DLQTR
76
VRQLE
81
SCECH
86
PASPQ
91
CWGLG
96
RAWPE
101
GARWE
106
PDACT
111
ACVCQ
116
DGAAH
121
CGPQA
126
HLPHC
131
RGCSQ
136
NGQTY
141
GNGET
146
FSPDA
151
CTTCR
156
CLEGT
161
ITCNQ
166
KPCPR
171
GPCPE
176
PGACC
181
PHCKP
186
GCDYE
191
GQLYE
196
EGVTF
201
LSSSN
206
PCLQC
211
TCLRS
216
RVRCM
221
ALKCP
226
PSPCP
231
EPVLR
236
PGHCC
241
PTCQG
246
CTEGG
251
SHWEH
256
GQEWT
261
TPGDP
266
CRICR
271
CLEGH
276
IQCRQ
281
RECAS
286
LCPYP
291
ARPLP
296
GTCCP
301
VCDGC
306
FLNGR
311
EHRSG
316
EPVGS
321
GDPCS
326
HCRCA
331
NGSVQ
336
CEPLP
341
CPPVP
346
CRHPG
351
KIPGQ
356
CCPVC
361
DGCEY
366
QGHQY
371
QSQET
376
FRLQE
381
RGLCV
386
RCSCQ
391
AGEVS
396
CEEQE
401
CPVTP
406
CALPA
411
SGRQL
416
CPACE
421
LDGEE
426
FAEGV
431
QWEPD
436
GRPCT
441
ACVCQ
446
DGVPK
451
CGAVL
456
CPPAP
461
CQHPT
466
QPPGA
471
CCPSC
476
DSCTY
481
HSQVY
486
ANGQN
491
FTDAD
496
SPCHA
501
CHCQD
506
GTVTC
511
SLVDC
516
PPTTC
521
ARPQS
526
GPGQC
531
CPRCP
536
DCILE
541
EEVFV
546
DGESF
551
SHPRD
556
PCQEC
561
RCQEG
566
HAHCQ
571
PRPCP
576
RAPCA
581
HPLPG
586
TCCPN
591
DCSGC
596
AFGGK
601
EYPSG
606
ADFPH
611
PSDPC
616
RLCRC
621
LSGNV
626
QCLAR
631
RCVPL
636
PCPEP
641
VLLPG
646
ECCPQ
651
CPAAP
656
APAGC
661
PRPGA
666
AHARH
671
QEYFS
676
PPGDP
681
CRRCL
686
CLDGS
691
VSCQR
696
LPCPP
701
APCAH
706
PRQGP
711
CCPSC
716
DGCLY
721
QGKEF
726
ASGER
731
FPSPT
736
AACHL
741
CLCWE
746
GSVSC
751
EPKAC
756
APALC
761
PFPAR
766
GDCCP
771
DCDGE
776
GHGIG
781
SCRGG
786
MRETR
791
GLGQN
796
NLYCP
801
RVDLK
806
YLLQ
811
Mutation Information
DNA mutation:
None
Peptide Range:
430 ~ 454
Mut AA position:
440 (13 in Wild Type peptide)
Alignment
Wild Type:
"EFAEGVQWEPDGRPCTACVCQDGVP
||||||||||||.||||||||||||
Mutant:
EFAEGVQWEPDGWPCTACVCQDGVP"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) KCP

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay