Immunogenicity 10547

summary
Sample ID
3812
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
MATN2
Transcript ID
uc010mbi.1
HLA INFO
C*07:02
TCR INFO

No TCR info found!

T cell Tumor cell C*07:02
sequence
Full length protein sequence (752 aa)
MRHLS
1
TGTMT
6
GLAIQ
11
YALNI
16
AFSEA
21
EGARP
26
LRENV
31
PRVIM
36
IVTDG
41
RPQDS
46
VAEVA
51
AKARD
56
TGILI
61
FAIGV
66
GQVDF
71
NTLKS
76
IGSEP
81
HEDHV
86
FLVAN
91
FSQIE
96
TLTSV
101
FQKKL
106
CTAHM
111
CSTLE
116
HNCAH
121
FCINI
126
PGSYV
131
CRCKQ
136
GYILN
141
SDQTT
146
CRTVD
151
YCASE
156
NHGCE
161
HECVN
166
ADGSY
171
LCQCH
176
EGFAL
181
NPDKK
186
TCTKI
191
DYCAS
196
SNHGC
201
QHECV
206
NTDDS
211
YSCHC
216
LKGFT
221
LNPDK
226
KTCRR
231
INYCA
236
LNKPG
241
CEHEC
246
VNMEE
251
SYYCR
256
CHRGY
261
TLDPN
266
GKTCS
271
RVDHC
276
AQQDH
281
GCEQL
286
CLNTE
291
DSFVC
296
QCSEG
301
FLINE
306
DLKTC
311
SRVDY
316
CLLSD
321
HGCEY
326
SCVNM
331
DRSFA
336
CQCPE
341
GHVLR
346
SDGKT
351
CAKLD
356
SCALG
361
DHGCE
366
HSCVS
371
SEDSF
376
VCQCF
381
EGYIL
386
REDGK
391
TCRRK
396
DVCQA
401
IDHGC
406
EHICV
411
NSDDS
416
YTCEC
421
LEGFR
426
LAEDG
431
KRCRR
436
KDVCK
441
STHHG
446
CEHIC
451
VNNGN
456
SYICK
461
CSEGF
466
VLAED
471
GRRCK
476
KCTEG
481
PIDLV
486
FVIDG
491
SKSLG
496
EENFE
501
VVKQF
506
VTGII
511
DSLTI
516
SPKAA
521
RVGLL
526
QYSTQ
531
VHTEF
536
TLRNF
541
NSAKD
546
MKKAV
551
AHMKY
556
MGKGS
561
MTGLA
566
LKHMF
571
ERSFT
576
QGEGA
581
RPLST
586
RVPRA
591
AIVFT
596
DGRAQ
601
DDVSE
606
WASKA
611
KANGI
616
TMYAV
621
GVGKA
626
IEEEL
631
QEIAS
636
EPTNK
641
HLFYA
646
EDFST
651
MDEIS
656
EKLKK
661
GICEA
666
LEDSD
671
GRQDS
676
PAGEL
681
PKTVQ
686
QPTVQ
691
HRYLF
696
EEDNL
701
LRSTQ
706
KLSHS
711
TKPSG
716
SPLEE
721
KHDQC
726
KCENL
731
IMFQN
736
LANEE
741
VRKLT
746
QR
751
Mutation Information
DNA mutation:
None
Peptide Range:
134 ~ 158
Mut AA position:
146 (13 in Wild Type peptide)
Alignment
Wild Type:
"YVCRCKQGYILNSDQTTCRTVDYCA
||||||||||||.||||||||||||
Mutant:
YVCRCKQGYILNLDQTTCRTVDYCA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) MATN2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

None

Assay

IFNg ELISPOT assay