Immunogenicity 10554

summary
Sample ID
3812
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
HHIPL1
Transcript ID
NM_001127258
HLA INFO
DRB*07:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*07:01
sequence
Full length protein sequence (782 aa)
MARAR
1
AGALL
6
ALWVL
11
GAAAH
16
PQCLD
21
FRPPF
26
RPTQP
31
LRLCA
36
QYSDF
41
GCCDE
46
GRDAE
51
LTRRF
56
WALAS
61
RVDAA
66
EWAAC
71
AGYAR
76
DLLCQ
81
ECSPY
86
AAHLY
91
DAEDP
96
FTPLR
101
TVPGL
106
CQDYC
111
LDMWH
116
KCRGL
121
FRHLS
126
TDQEL
131
WALEG
136
NLARF
141
CRYLS
146
LDDTD
151
YCFPY
156
LLVNK
161
NLNSN
166
LGHVV
171
ADAKG
176
CLQLC
181
LEEVA
186
NGLRN
191
PVAMV
196
HARDG
201
THRFF
206
VAEQV
211
GLVWA
216
YLPDR
221
SRLGK
226
PFLNI
231
SRVVL
236
TSPWE
241
GDERG
246
FLGIA
251
FHPSF
256
QHNRR
261
LYVYY
266
SVGIR
271
SSEWI
276
RISEF
281
RVSED
286
DENAV
291
DHSSE
296
RIILE
301
VKEPA
306
SNHNG
311
GQLLF
316
GDDGY
321
LYIFT
326
GDGGM
331
AGDPF
336
GTFGN
341
AQNKS
346
ALLGK
351
VLRID
356
VDRKE
361
RGLPY
366
GIPPD
371
NPFVG
376
DPAAQ
381
PEVYA
386
LGVRN
391
MWRCS
396
FDRGD
401
PSSGT
406
GRGRL
411
FCGDV
416
GQNKF
421
EEVDV
426
VERGG
431
NYGWR
436
AREGF
441
ECYDR
446
SLCAN
451
TSLND
456
LLPIF
461
AYPHT
466
VGKSV
471
TGGYV
476
YRGCE
481
YPNLN
486
GLYIF
491
GDFMS
496
GRLMS
501
LQENP
506
GTGQW
511
QYSEI
516
CMGHG
521
QTCEF
526
PGLIN
531
NYYPY
536
IISFG
541
EDEAG
546
ELYFM
551
STGEP
556
SATAP
561
RGVVY
566
KIIDA
571
SRRAP
576
PGKCQ
581
IQPAQ
586
VKIRS
591
RLIPF
596
VPKEK
601
FIPKT
606
RSTPR
611
PTARA
616
PTRAP
621
RRGRP
626
TAAPP
631
APTPR
636
PARPT
641
QQPGS
646
RRGGG
651
RRRGR
656
LNSAS
661
RAFRD
666
GEVRL
671
VRPAG
676
LSSGS
681
GRVEV
686
FVGGR
691
WGTVC
696
DDSWN
701
ISGAA
706
VVCRQ
711
LGFAY
716
AVRAV
721
KRAEF
726
GQGGS
731
LPILL
736
DDVRC
741
AGWER
746
NLLEC
751
QHNGV
756
GTHNC
761
EHDED
766
AGVVC
771
SHQNP
776
DL
781
Mutation Information
DNA mutation:
None
Peptide Range:
654 ~ 678
Mut AA position:
666 (13 in Wild Type peptide)
Alignment
Wild Type:
"GGRRRGRLNSASRAFRDGEVRLVRP
||||||||||||.||||||||||||
Mutant:
GGRRRGRLNSASWAFRDGEVRLVRP"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) HHIPL1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

None

Assay

IFNg ELISPOT assay