Immunogenicity 10585

summary
Sample ID
3812
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
ADCY1
Transcript ID
NM_001281768
HLA INFO
DQA*02:01 / DQB*06:03
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*02:01 DQB*06:03
sequence
Full length protein sequence (338 aa)
MYGVF
1
VRILT
6
ERSQR
11
KAFLQ
16
ARSCI
21
EDRLR
26
LEDEN
31
EKQER
36
LLMSL
41
LPRNV
46
AMEMK
51
EDFLK
56
PPERI
61
FHKIY
66
IQRHD
71
NVSIL
76
FADIV
81
GFTGL
86
ASQCT
91
AQELV
96
KLLNE
101
LFGKF
106
DELAT
111
ENHCR
116
RIKIL
121
GDCYY
126
CVSGL
131
TQPKT
136
DHAHC
141
CVEMG
146
LDMID
151
TITSV
156
AEATE
161
VDLNM
166
RVGLH
171
TGRVL
176
CGVLG
181
LRKWQ
186
YDVWS
191
NDVTL
196
ANVME
201
AAGLP
206
GKVHI
211
TKTTL
216
ACLNG
221
DYEVE
226
PGYGH
231
ERNSF
236
LKTHN
241
IETFF
246
IVPSH
251
RRKIF
256
PGLIL
261
SDIKP
266
AKRMK
271
FKTVC
276
YLLVQ
281
LMHCR
286
KMFKA
291
EIPFS
296
NVMTC
301
EDDDK
306
VQIHP
311
SLSGL
316
DVLLG
321
FWSPT
326
LQRGR
331
LCT
336
Mutation Information
DNA mutation:
None
Peptide Range:
321 ~ 338
Mut AA position:
333 (13 in Wild Type peptide)
Alignment
Wild Type:
"DVLLGFWSPTLQRGRLCT
||||||||||||.|||||
Mutant:
DVLLGFWSPTLQWGRLCT"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ADCY1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

None

Assay

IFNg ELISPOT assay