Immunogenicity 10605

summary
Sample ID
3812
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
EPB41
Transcript ID
NM_001166005
HLA INFO
B*07:02
TCR INFO

No TCR info found!

T cell Tumor cell B*07:02
sequence
Full length protein sequence (864 aa)
MTTEK
1
SLVTE
6
AENSQ
11
HQQKE
16
EGEEA
21
INSGQ
26
QEPQQ
31
EESCQ
36
TAAEG
41
DNWCE
46
QKLKA
51
SNGDT
56
PTHED
61
LTKNK
66
ERTSE
71
SRGLS
76
RLFSS
81
FLKRP
86
KSQVS
91
EEEGK
96
EVESD
101
KEKGE
106
GGQKE
111
IEFGT
116
SLDEE
121
IILKA
126
PIAAP
131
EPELK
136
TDPSL
141
DLHSL
146
SSAET
151
QPAQE
156
ELRED
161
PDFEI
166
KEGEG
171
LEECS
176
KIEVK
181
EESPQ
186
SKAET
191
ELKAS
196
QKPIR
201
KHRNM
206
HCKVS
211
LLDDT
216
VYECV
221
VEKHA
226
KGQDL
231
LKRVC
236
EHLNL
241
LEEDY
246
FGLAI
251
WDNAT
256
SKTWL
261
DSAKE
266
IKKQV
271
RGVPW
276
NFTFN
281
VKFYP
286
PDPAQ
291
LTEDI
296
TRYYL
301
CLQLR
306
QDIVA
311
GRLPC
316
SFATL
321
ALLGS
326
YTIQS
331
ELGDY
336
DPELH
341
GVDYV
346
SDFKL
351
APNQT
356
KELEE
361
KVMEL
366
HKSYR
371
SMTPA
376
QADLE
381
FLENA
386
KKLSM
391
YGVDL
396
HKAKD
401
LEGVD
406
IILGV
411
CSSGL
416
LVYKD
421
KLRIN
426
RFPWP
431
KVLKI
436
SYKRS
441
SFFIK
446
IRPGE
451
QEQYE
456
STIGF
461
KLPSY
466
RAAKK
471
LWKVC
476
VEHHT
481
FFRLT
486
STDTI
491
PKSKF
496
LALGS
501
KFRYS
506
GRTQA
511
QTRQA
516
SALID
521
RPAPH
526
FERTA
531
SKRAS
536
RSLDG
541
AAAVD
546
SADRS
551
PRPTS
556
APAIT
561
QGQVA
566
EGGVL
571
DASAK
576
KTVVP
581
KAQKE
586
TVKAE
591
VKKED
596
EPPEQ
601
AEPEP
606
TEAWK
611
VEKTH
616
IEVTV
621
PTSNG
626
DQTQK
631
LAEKT
636
EDLIR
641
MRKKK
646
RERLD
651
GENIY
656
IRHSN
661
LMLED
666
LDKSQ
671
EEIKK
676
HHASI
681
SELKK
686
NFMES
691
VPEPR
696
PSEWD
701
KRLST
706
HSPFR
711
TLNIN
716
GQIPT
721
GEGPP
726
LVKTQ
731
TVTIS
736
DNANA
741
VKSEI
746
PTKDV
751
PIVHT
756
ETKTI
761
TYEAA
766
QTDDN
771
SGDLD
776
PGVLL
781
TAQTI
786
TSETP
791
SSTTT
796
TQITK
801
TVKGG
806
ISETR
811
IEKRI
816
VITGD
821
ADIDH
826
DQVLV
831
QAIKE
836
AKEQH
841
PDMSV
846
TKVVV
851
HQETE
856
IADE
861
Mutation Information
DNA mutation:
None
Peptide Range:
632 ~ 656
Mut AA position:
644 (13 in Wild Type peptide)
Alignment
Wild Type:
"QTQKLAEKTEDLIRMRKKKRERLDG
||||||||||||.||||||||||||
Mutant:
QTQKLAEKTEDLVRMRKKKRERLDG"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) EPB41

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

None

Assay

IFNg ELISPOT assay