Immunogenicity 10613
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
PLEKHG4B
Transcript ID
NM_052909
HLA INFO
B*15:01
TCR INFO
No TCR info found!
Full length protein sequence (1627 aa)
MGFST
1
ADGGG
6
GPGAR
11
DLESL
16
DACIQ
21
RTLSA
26
LYPPF
31
EATAA
36
TVLWQ
41
LFSVA
46
ERCHG
51
GDGLH
56
CLTSF
61
LLPAK
66
RALQH
71
LQQEA
76
CARYR
81
GLVFL
86
HPGWP
91
LCAHE
96
KVVVQ
101
LASLH
106
GVRLQ
111
PGDFY
116
LQVTS
121
AGKQS
126
ARLVL
131
KCLSR
136
LGRGT
141
EEVTV
146
PEAMY
151
GCVFT
156
GAFLE
161
WVNRE
166
RRHVP
171
LQTCL
176
LTSGL
181
AVHRA
186
PWSDV
191
TDPVF
196
VPSPG
201
AILQS
206
YSSCT
211
GPERL
216
PSSPS
221
EAPVP
226
TQATA
231
GPHFQ
236
GSASC
241
PDTLT
246
SPCRR
251
GHTGS
256
DQLRH
261
LPYPE
266
RAELG
271
SPRTL
276
SGSSD
281
RDFEK
286
VSPSE
291
QGPRM
296
PPENC
301
GGSGE
306
RPDPM
311
DQEDR
316
PKALT
321
FHTDL
326
GIPSS
331
RRRPP
336
GDPTC
341
VQPRR
346
WFRES
351
YMEAL
356
RNPMP
361
LGSSE
366
EALGD
371
LACSS
376
LTGAS
381
RDLGT
386
GAVAS
391
GTQEE
396
TSGPR
401
GDPQQ
406
TPSLE
411
KERHT
416
PSRTG
421
PGAAG
426
RTLPR
431
RSRSW
436
ERAPR
441
SSRGA
446
QAAAC
451
HTSHH
456
SAGSR
461
PGGHL
466
GGQAV
471
GTPNC
476
VPVEG
481
PGCTK
486
EEDVL
491
ASSAC
496
VSTDG
501
GSLHC
506
HNPSG
511
PSDVP
516
ARQPH
521
PEQEG
526
WPPGT
531
GDFPS
536
QVPKQ
541
VLDVS
546
QELLQ
551
SGVVT
556
LPGTR
561
DRHGR
566
AVVQV
571
RTRSL
576
LWTRE
581
HSSCA
586
ELTRL
591
LLYFH
596
SIPRK
601
EVRDL
606
GLVVL
611
VDARR
616
SPAAP
621
AVSQA
626
LSGLQ
631
NNTSP
636
IIHSI
641
LLLVD
646
KESAF
651
RPDKD
656
AIIQC
661
EVVSS
666
LKAVH
671
KFVDS
676
CQLTA
681
DLDGS
686
FPYSH
691
GDWIC
696
FRQRL
701
EHFAA
706
NCEEA
711
IIFLQ
716
NSFCS
721
LNTHR
726
TPRTA
731
QEVAE
736
LIDQH
741
ETMMK
746
LVLED
751
PLLVS
756
LRLEG
761
GTVLA
766
RLRRE
771
ELGTE
776
DSRDT
781
LEAAT
786
SLYDR
791
VDEEV
796
HRLVL
801
TSNNR
806
LQQLE
811
HLREL
816
ASLLE
821
GNDQQ
826
SCQKG
831
LQLAK
836
ENPQR
841
TEEMV
846
QDFRR
851
GLSAV
856
VSQAE
861
CREGE
866
LARWT
871
RSSEL
876
CETVS
881
SWMGP
886
LDPEA
891
CPSSP
896
VAECL
901
RSCHQ
906
EATSV
911
AAEAF
916
PGAGV
921
AVLKP
926
HALGK
931
PWASQ
936
QDLWL
941
QYPQT
946
RLRLE
951
EALSE
956
AAPDP
961
SLPPL
966
AQSPP
971
KHERA
976
QEAMR
981
RHQKP
986
PSFPS
991
TDSGG
996
GAWEP
1001
AQPLS
1006
GLPGR
1011
ALLCG
1016
QDGET
1021
LRPGL
1026
CALWD
1031
PLSLL
1036
RGLPG
1041
AGATT
1046
AHLED
1051
SSACS
1056
SEPTQ
1061
TLASR
1066
PRKHP
1071
QKKMI
1076
KKTQS
1081
FEIPQ
1086
PDSGP
1091
RDSCQ
1096
PDHTS
1101
VFSKG
1106
LEVTS
1111
TVATE
1116
KKLPL
1121
WQHAR
1126
SPPVT
1131
QSRSL
1136
SSPSG
1141
LHPAE
1146
EDGRQ
1151
QVGSS
1156
RLRHI
1161
MAEMI
1166
ATERE
1171
YIRCL
1176
GYVID
1181
NYFPE
1186
MERMD
1191
LPQGL
1196
RGKHH
1201
VIFGN
1206
LEKLH
1211
DFHQQ
1216
HFLRE
1221
LERCQ
1226
HCPLA
1231
VGRSF
1236
LRHEE
1241
QFGMY
1246
VIYSK
1251
NKPQS
1256
DALLS
1261
SHGNA
1266
FFKDK
1271
QRELG
1276
DKMDL
1281
ASYLL
1286
RPVQR
1291
VAKYA
1296
LLLQD
1301
LLKEA
1306
SCGLA
1311
QGQEL
1316
GELRA
1321
AEVVV
1326
CFQLR
1331
HGNDL
1336
LAMDA
1341
IRGCD
1346
VNLKE
1351
QGQLR
1356
CRDEF
1361
IVCCG
1366
RKKYL
1371
RHVFL
1376
FEDLI
1381
LFSKT
1386
QKVEG
1391
SHDVY
1396
LYKQS
1401
FKTAE
1406
IGMTE
1411
NVGDS
1416
GLRFE
1421
IWFRR
1426
RRKSQ
1431
DTYIL
1436
QASSA
1441
EVKSA
1446
WTDVI
1451
GRILW
1456
RQALK
1461
SRELR
1466
IQEMA
1471
SMGIG
1476
NQPFM
1481
DVKPR
1486
DRTPD
1491
CAVIS
1496
DRAPK
1501
CAVMS
1506
DRVPD
1511
SIVKG
1516
TESQM
1521
RGSTA
1526
VSSSD
1531
HAAPF
1536
KRPHS
1541
TISDS
1546
STSSS
1551
SSQSS
1556
SILGS
1561
LGLLV
1566
SSSPA
1571
HPGLW
1576
SPAHS
1581
PWSSD
1586
IRACV
1591
EEDEP
1596
EPELE
1601
TGTQA
1606
AVCEG
1611
APAVL
1616
LSRTR
1621
QA
1626
Mutation Information
DNA mutation:
None
Peptide Range:
1449 ~ 1473
Mut AA position:
None (None in Wild Type peptide)
Alignment
Wild Type:
"SAWTDVIGRILWRQALKSRELRIQE
||||||||||||.||||||||||||
Mutant:
SAWTDVIGRILWWQALKSRELRIQE"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) PLEKHG4B
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay