Immunogenicity 10637

summary
Sample ID
3812
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
C8orf74
Transcript ID
NM_001040032
HLA INFO
DQA*01:03 / DQB*02:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*02:02
sequence
Full length protein sequence (294 aa)
MALLT
1
PQGVK
6
EVFQF
11
QRPQG
16
RERLR
21
RLLNW
26
EEFDE
31
QRDSR
36
RSILL
41
DTLYE
46
SIIFA
51
VGKGF
56
PWVEV
61
AQVVK
66
FTEEL
71
LRETK
76
GCSIT
81
EAVTI
86
LGNKL
91
RDYRG
96
HFNTT
101
HLLAL
106
CDYFH
111
HTFIR
116
HYKLY
121
QYVLG
126
QDQQV
131
DLTVA
136
HLEVC
141
MPPHP
146
LPLAE
151
GMDRD
156
LWIHE
161
QQVAT
166
LTEAE
171
AQKRA
176
DVLLL
181
KEALR
186
LEREN
191
SLQKA
196
FAAAA
201
PAQPG
206
QVLER
211
QELES
216
LICQA
221
VHTQM
226
ELLQE
231
LLQRQ
236
IQNTF
241
AILDL
246
KLQKK
251
TLNLN
256
APTPI
261
PPPIT
266
SHAGQ
271
EEALK
276
PQRAS
281
KGKKA
286
KARK
291
Mutation Information
DNA mutation:
None
Peptide Range:
143 ~ 167
Mut AA position:
155 (13 in Wild Type peptide)
Alignment
Wild Type:
"EVCMPPHPLPLAEGMDRDLWIHEQQ
||||||||||||.||||||||||||
Mutant:
EVCMPPHPLPLAKGMDRDLWIHEQQ"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) C8orf74

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

None

Assay

IFNg ELISPOT assay