Immunogenicity 1064

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
TARSL2
Transcript ID
ENST00000335968
HLA INFO
C*16:01
TCR INFO

No TCR info found!

T cell Tumor cell C*16:01
sequence
Full length protein sequence (802 aa)
MAAEA
1
LAAEA
6
VASRL
11
ERQEE
16
DIRWL
21
WSEVE
26
RLRDE
31
QLNAP
36
YSCQA
41
EGPCL
46
TREVA
51
QLRAE
56
NCDLR
61
HRLCS
66
LRLCL
71
AEERS
76
RQATL
81
ESAEL
86
EAAQE
91
AGAQP
96
PPSQS
101
QDKDM
106
KKKKM
111
KESEA
116
DSEVK
121
HQPIF
126
IKERL
131
KLFEI
136
LKKDH
141
QLLLA
146
IYGKK
151
GDTSN
156
IITVR
161
VADGQ
166
TVQGE
171
VWKTT
176
PYQVA
181
AEISQ
186
ELAES
191
TVIAK
196
VNGEL
201
WDLDR
206
PLEGD
211
SSLEL
216
LTFDN
221
EEAQA
226
VYWHS
231
SAHIL
236
GEAME
241
LYYGG
246
HLCYG
251
PPIEN
256
GFYYD
261
MFIED
266
RAVSS
271
TELSA
276
LENIC
281
KAIIK
286
EKQPF
291
ERLEV
296
SKEIL
301
LEMFK
306
YNKFK
311
CRILN
316
EKVNT
321
ATTTV
326
YRCGP
331
LIDLC
336
KGPHV
341
RHTGK
346
IKTIK
351
IFKNS
356
STYWE
361
GNPEM
366
ETLQR
371
IYGIS
376
FPDNK
381
MMRDW
386
EKFQE
391
EAKNR
396
DHRKI
401
GKEQE
406
LFFFH
411
DLSPG
416
SCFFL
421
PRGAF
426
IYNTL
431
TDFIR
436
EEYHK
441
RDFTE
446
VLSPN
451
MYNSK
456
LWEAS
461
GHWQH
466
YSENM
471
FTFEI
476
EKDTF
481
ALKPM
486
NCPGH
491
CLMFA
496
HRPRS
501
WREMP
506
IRFAD
511
FGVLH
516
RNELS
521
GTLSG
526
LTRVR
531
RFQQD
536
DAHIF
541
CTVEQ
546
IEEEI
551
KGCLQ
556
FLQSV
561
YSTFG
566
FSFQL
571
NLSTR
576
PENFL
581
GEIEM
586
WNEAE
591
KQLQN
596
SLMDF
601
GEPWK
606
MNPGD
611
GAFYG
616
PKIDI
621
KIKDA
626
IGRYH
631
QCATI
636
QLDFQ
641
LPIRF
646
NLTYV
651
SKDGD
656
DKKRP
661
VIIHR
666
AILGS
671
VERMI
676
AILSE
681
NYGGK
686
WPFWL
691
SPRQV
696
MVIPV
701
GPTCE
706
KYALQ
711
VSSEF
716
FEEGF
721
MADVD
726
LDHSC
731
TLNKK
736
IRNAQ
741
LAQYN
746
FILVV
751
GEKEK
756
IDNAV
761
NVRTR
766
DNKIH
771
GEILV
776
TSAID
781
KLKNL
786
RKTRT
791
LNAEE
796
AF
801
Mutation Information
DNA mutation:
None
Peptide Range:
436 ~ 460
Mut AA position:
448 (13 in Wild Type peptide)
Alignment
Wild Type:
"TDFIREEYHKRDFTEVLSPNMYNSK
||||||||||||.||||||||||||
Mutant:
TDFIREEYHKRDITEVLSPNMYNSK"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) TARSL2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay