Immunogenicity 10668

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
PRAMEF11
Transcript ID
NM_001146344
HLA INFO
DQA*01:02 / DQB*06:01
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:02 DQB*06:01
sequence
Full length protein sequence (478 aa)
MKMSI
1
RIPPR
6
LLELA
11
GRSLL
16
RDQAL
21
AVSTL
26
EELPT
31
ELFPP
36
LFMEA
41
FSRRR
46
CEALK
51
LMVQA
56
WPFRR
61
LPLRP
66
LIKMP
71
CLEAF
76
QAVLD
81
GLDAL
86
LTQGV
91
RPRRW
96
KLQVL
101
DLQDV
106
CENFW
111
MVWSE
116
AMAHG
121
CFLNA
126
KRNKK
131
PVQDC
136
PRMRG
141
RQPLT
146
VFVEL
151
WLKNR
156
TLDEY
161
LTCLL
166
LWVKQ
171
RRDLL
176
HLCCK
181
KLKIL
186
GMPFR
191
NIRSI
196
LKMVN
201
LDCIQ
206
EVEVN
211
CKWIL
216
PILTQ
221
FTPYL
226
GHLRN
231
LQKLV
236
LSHMD
241
VSRYV
246
SPEQK
251
KEIVT
256
QFTTQ
261
FLKLR
266
CLQKL
271
YMNSV
276
SFLEG
281
HLDQL
286
LSCLK
291
TSLKV
296
LTITN
301
CVLLE
306
SDLKH
311
LSQCP
316
SISQL
321
KTLDL
326
SGIRL
331
TNYSL
336
VPLQI
341
LLEKV
346
AATLE
351
YLDLD
356
DCGII
361
DSQVN
366
AILPA
371
LSRCF
376
ELNTF
381
SFCGN
386
PICMA
391
TLENL
396
LSHTI
401
ILKNL
406
CLELY
411
PAPQE
416
SYGAD
421
GTLCW
426
SRFAQ
431
IRAEL
436
MKKVR
441
HLRHP
446
KRILF
451
CTDNC
456
PDHGD
461
RSFYD
466
LEADQ
471
YCC
476
Mutation Information
DNA mutation:
None
Peptide Range:
81 ~ 105
Mut AA position:
None (None in Wild Type peptide)
Alignment
Wild Type:
"QAVLDGLDALLTQGVRPRRWKLQVL
||||||||||||.||||||||||||
Mutant:
QAVLDGLDALLTHGVRPRRWKLQVL"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PRAMEF11

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay