Immunogenicity 1069
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
COL6A5
Transcript ID
ENST00000265379
HLA INFO
C*01:02
TCR INFO
No TCR info found!
Full length protein sequence (2615 aa)
MKILL
1
IIFVL
6
IIWTE
11
TLADQ
16
SPGPG
21
PVYAD
26
VVFLV
31
DSSDH
36
LGPKS
41
FPFVK
46
TFINK
51
MINSL
56
PIEAN
61
KYRVA
66
LAQYS
71
DEFHS
76
EFHLS
81
TFKGR
86
SPMLN
91
HLKKN
96
FQFIG
101
GSLQI
106
GKALQ
111
EAHRT
116
YFSAP
121
INGRD
126
RKQFP
131
PILVV
136
LASAE
141
SEDEV
146
EEASK
151
ALQKD
156
GVKII
161
SVGVQ
166
KASEE
171
NLKAM
176
ATSHF
181
HFNLR
186
TIRDL
191
STFSQ
196
NMTQI
201
IKDVT
206
KYKEG
211
AVDAD
216
MQVHF
221
PISCQ
226
KDSLA
231
DLVFL
236
VDESL
241
GTGGN
246
LRHLQ
251
TFLEN
256
ITSSM
261
DVKEN
266
CMRLG
271
LMSYS
276
NSAKT
281
ISFLK
286
SSTTQ
291
SEFQQ
296
QIKNL
301
SIQVG
306
KSNTG
311
AAIDQ
316
MRRDG
321
FSESY
326
GSRRA
331
QGVPQ
336
IAVLV
341
THRPS
346
DDEVH
351
DAALN
356
LRLED
361
VNVFA
366
LSIQG
371
ANNTQ
376
LEEIV
381
SYPPE
386
QTIST
391
LKSYA
396
DLETY
401
STKFL
406
KKLQN
411
EIWSQ
416
ISTYA
421
EQRNL
426
DKTGC
431
VDTKE
436
ADIHF
441
LIDGS
446
SSIQE
451
KQFEQ
456
IKRFM
461
LEVTE
466
MFSIG
471
PDKVR
476
VGVVQ
481
YSDDT
486
EVEFY
491
ITDYS
496
NDIDL
501
RKAIF
506
NIKQL
511
TGGTY
516
TGKAL
521
DYILQ
526
IIKNG
531
MKDRM
536
SKVPC
541
YLIVL
546
TDGMS
551
TDRVV
556
EPAKR
561
LRAEQ
566
ITVHA
571
VGIGA
576
ANKIE
581
LQEIA
586
GKEER
591
VSFGQ
596
NFDAL
601
KSIKN
606
EVVRE
611
ICAEK
616
GCEDM
621
KADIM
626
FLVDS
631
SWSIG
636
NENFR
641
KMKIF
646
MKNLL
651
TKIQI
656
GADKT
661
QIGVV
666
QFSDK
671
TKEEF
676
QLNRY
681
FTQQE
686
ISDAI
691
DRMSL
696
INEGT
701
LTGKA
706
LNFVG
711
QYFTH
716
SKGAR
721
LGAKK
726
FLILI
731
TDGVA
736
QDDVR
741
DPARI
746
LRGKD
751
VTIFS
756
VGVYN
761
ANRSQ
766
LEEIS
771
GDSSL
776
VFHVE
781
NFDHL
786
KALER
791
KLIFR
796
VCALH
801
DCKRI
806
TLLDV
811
VFVLD
816
HSGSI
821
KKQYQ
826
DHMIN
831
LTIHL
836
VKKAD
841
VGRDR
846
VQFGA
851
LKYSD
856
QPNIL
861
FYLNT
866
YSNRS
871
AIIEN
876
LRKRR
881
DTGGN
886
TYTAK
891
ALKHA
896
NALFT
901
EEHGS
906
RIKQN
911
VKQML
916
IVITD
921
GESHD
926
HDQLN
931
DTALE
936
LRNKG
941
ITIFA
946
VGVGK
951
ANQKE
956
LEGMA
961
GNKNN
966
TIYVD
971
NFDKL
976
KDVFT
981
LVQER
986
MCTEA
991
PEVCH
996
LQEAD
1001
VIFLC
1006
DGSDR
1011
VSNSD
1016
FVTMT
1021
TFLSD
1026
LIDNF
1031
DIQSQ
1036
RMKIG
1041
MAQFG
1046
SNYQS
1051
IIELK
1056
NSLTK
1061
TQWKT
1066
QIQNV
1071
SKSGG
1076
FPRID
1081
FALKK
1086
VSNMF
1091
NLHAG
1096
GRRNA
1101
GVPQT
1106
LVVIT
1111
SGDPR
1116
YDVAD
1121
AVKTL
1126
KDLGI
1131
CVLVL
1136
GIGDV
1141
YKEHL
1146
LPITG
1151
NSEKI
1156
ITFQD
1161
FDKLK
1166
NVDVK
1171
KRIIR
1176
EICQS
1181
CGKTN
1186
CFMDI
1191
VVGFD
1196
ISTHV
1201
QGQPL
1206
FQGHP
1211
QLESY
1216
LPGIL
1221
EDISS
1226
IKGVS
1231
CGAGT
1236
EAQVS
1241
LAFKV
1246
NSDQG
1251
FPAKF
1256
QIYQK
1261
AVFDS
1266
LLQVN
1271
VSGPT
1276
HLNAQ
1281
FLRSL
1286
WDTFK
1291
DKSAS
1296
RGQVL
1301
LIFSD
1306
GLQSE
1311
SNIML
1316
ENQSD
1321
RLREA
1326
GLDAL
1331
LVVSL
1336
NTTAH
1341
HEFSS
1346
FEFGK
1351
RFDYR
1356
THLTI
1361
GMREL
1366
GKKLS
1371
QYLGN
1376
IAERT
1381
CCCTF
1386
CKCPG
1391
IPGPH
1396
GTRGL
1401
QAMKG
1406
SQGLK
1411
GSRGH
1416
RGEDG
1421
NPGVR
1426
GDTGP
1431
QGDKG
1436
IAGCP
1441
GAWGQ
1446
KGLKG
1451
FSGPK
1456
GGHGD
1461
DGIDG
1466
LDGEE
1471
GCHGF
1476
PGIKG
1481
EKGDP
1486
GSQGS
1491
PGSRG
1496
APGQY
1501
GEKGF
1506
PGDPG
1511
NPGQN
1516
NNIKG
1521
QKGSK
1526
GEQGR
1531
QGRSG
1536
QKGVQ
1541
GSPSS
1546
RGSRG
1551
REGQR
1556
GLRGV
1561
SGEPG
1566
NPGPT
1571
GTLGA
1576
EGLQG
1581
PQGSQ
1586
GNPGR
1591
KGEKG
1596
SQGQK
1601
GPQGS
1606
PGLMG
1611
AKGST
1616
GRPGL
1621
LGKKG
1626
EPGLP
1631
GDLGP
1636
VGQTG
1641
QRGRQ
1646
GDSGI
1651
PGYGQ
1656
MGRKG
1661
VKGPR
1666
GFPGD
1671
AGQKG
1676
DIGNP
1681
GIPGG
1686
PGPKG
1691
FRGLA
1696
LTVGL
1701
KGEEG
1706
SRGLP
1711
GPPGQ
1716
RGIKG
1721
MAGQP
1726
VYSQC
1731
DLIRF
1736
LREHS
1741
LCSLE
1746
KCPAY
1751
PTELV
1756
FALDN
1761
SYDVT
1766
EESFN
1771
KTRDI
1776
ITSIV
1781
NDLNI
1786
RENNC
1791
PVGAR
1796
VAMVS
1801
YNSGT
1806
SYLIR
1811
WSDYN
1816
RKKQL
1821
LQQLS
1826
QIKYQ
1831
DTTEP
1836
RDVGN
1841
AMRFV
1846
TRNVF
1851
KRTYA
1856
GANVR
1861
RVAVF
1866
FSNGQ
1871
TASRS
1876
SIITA
1881
TMEFS
1886
ALDIS
1891
PTVFA
1896
FDERV
1901
FLEAF
1906
GFDNT
1911
GTFQV
1916
IPVPP
1921
NGENQ
1926
TLERL
1931
RRCAL
1936
CYDKC
1941
FPNAC
1946
IREAF
1951
LPEDS
1956
YMDVV
1961
FLIDN
1966
SRNIA
1971
KDEFK
1976
AVKAL
1981
VSSVI
1986
DNFNI
1991
ASDPL
1996
ISDSG
2001
DRIAL
2006
LSYSP
2011
WESSR
2016
RKMGT
2021
VKTEF
2026
DFITY
2031
DNQLL
2036
MKNHI
2041
QTSFQ
2046
QLNGE
2051
ATIGR
2056
ALLWT
2061
TENLF
2066
PETPY
2071
LRKHK
2076
VIFVV
2081
SAGEN
2086
YERKE
2091
FVKMM
2096
ALRAK
2101
CQGYV
2106
IFVIS
2111
LGSTR
2116
KDDME
2121
ELASY
2126
PLDQH
2131
LIQLG
2136
RIHKP
2141
DLNYI
2146
AKFLK
2151
PFLYS
2156
VRRGF
2161
NQYPP
2166
PMLED
2171
ACRLI
2176
NLGGE
2181
NIQND
2186
GFQFV
2191
TELQE
2196
DFLGG
2201
NGFIG
2206
QELNS
2211
GRESP
2216
FVKTE
2221
DNGSD
2226
YLVYL
2231
PSQMF
2236
EPQKL
2241
MINYE
2246
KDQKS
2251
AEIAS
2256
LTSGH
2261
ENYGR
2266
KEEPD
2271
HTYEP
2276
GDVSL
2281
QEYYM
2286
DVAFL
2291
IDASQ
2296
RVGSD
2301
EFKEV
2306
KAFIT
2311
SVLDY
2316
FHIAP
2321
TPLTS
2326
TLGDR
2331
VAVLS
2336
YSPPG
2341
YMPNT
2346
EECPV
2351
YLEFD
2356
LVTYN
2361
SIHQM
2366
KHHLQ
2371
DSQQL
2376
NGDVF
2381
IGHAL
2386
QWTID
2391
NVFVG
2396
TPNLR
2401
KNKVI
2406
FVISA
2411
GETNS
2416
LDKDV
2421
LRNVS
2426
LRAKC
2431
QGYSI
2436
FVFSF
2441
GPKHN
2446
DKELE
2451
ELASH
2456
PLDHH
2461
LVQLG
2466
RTHKP
2471
DWNYI
2476
IKFVK
2481
PFVHL
2486
IRRAI
2491
NKYPT
2496
EDMKA
2501
TCVNM
2506
TSPNP
2511
ENGGT
2516
ENTVL
2521
LLPGI
2526
YEIKT
2531
ENGDL
2536
FDEFD
2541
SQAQH
2546
LLVLG
2551
NNHSS
2556
GSETA
2561
TDLMQ
2566
KLYLL
2571
FSTEK
2576
LAMKD
2581
KEKAH
2586
LEEIS
2591
ALVVD
2596
KQQEK
2601
EDKEM
2606
EATDI
2611
Mutation Information
DNA mutation:
None
Peptide Range:
1377 ~ 1401
Mut AA position:
1389 (13 in Wild Type peptide)
Alignment
Wild Type:
"YLGNIAERTCCCTFCKCPGIPGPHG
||||||||||||.||||||||||||
Mutant:
YLGNIAERTCCCIFCKCPGIPGPHG"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) COL6A5
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay