Immunogenicity 10697

summary
Sample ID
3812
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
DHX29
Transcript ID
NM_019030
HLA INFO
DQA*01:03 / DQB*02:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*02:02
sequence
Full length protein sequence (1369 aa)
MGGKN
1
KKHKA
6
PAAAV
11
VRAAV
16
SASRA
21
KSAEA
26
GIAGE
31
AQSKK
36
PVSRP
41
ATAAA
46
AAAGS
51
REPRV
56
KQGPK
61
IYSFN
66
STNDS
71
SGPAN
76
LDKSI
81
LKVVI
86
NNKLE
91
QRIIG
96
VINEH
101
KKQNN
106
DKGMI
111
SGRLT
116
AKKLQ
121
DLYMA
126
LQAFS
131
FKTKD
136
IEDAM
141
TNTLL
146
YGGDL
151
HSALD
156
WLCLN
161
LSDDA
166
LPEGF
171
SQEFE
176
EQQPK
181
SRPKF
186
QSPQI
191
QATIS
196
PPLQP
201
KTKTY
206
EEDPK
211
SKPKK
216
EEKNM
221
EVNMK
226
EWILR
231
YAEQQ
236
NEEEK
241
NENSK
246
SLEEE
251
EKFDP
256
NERYL
261
HLAAK
266
LLDAK
271
EQAAT
276
FKLEK
281
NKQGQ
286
KEAQE
291
KIRKF
296
QREME
301
TLEDH
306
PVFNP
311
AMKIS
316
HQQNE
321
RKKPP
326
VATEG
331
ESALN
336
FNLFE
341
KSAAA
346
TEEEK
351
DKKKE
356
PHDVR
361
NFDYT
366
ARSWT
371
GKSPK
376
QFLID
381
WVRKN
386
LPKSP
391
NPSFE
396
KVPVG
401
RYWKC
406
RVRVI
411
KSEDD
416
VLVVC
421
PTILT
426
EDGMQ
431
AQHLG
436
ATLAL
441
YRLVK
446
GQSVH
451
QLLPP
456
TYRDV
461
WLEWS
466
DAEKK
471
REELN
476
KMETN
481
KPRDL
486
FIAKL
491
LNKLK
496
QQQQQ
501
QQQHS
506
ENKRE
511
NSEDP
516
EESWE
521
NLVSD
526
EDFSA
531
LSLES
536
ANVED
541
LEPVR
546
NLFRK
551
LQSTP
556
KYQKL
561
LKERQ
566
QLPVF
571
KHRDS
576
IVETL
581
KRHRV
586
VVVAG
591
ETGSG
596
KSTQV
601
PHFLL
606
EDLLL
611
NEWEA
616
SKCNI
621
VCTQP
626
RRISA
631
VSLAN
636
RVCDE
641
LGCEN
646
GPGGR
651
NSLCG
656
YQIRM
661
ESRAC
666
ESTRL
671
LYCTT
676
GVLLR
681
KLQED
686
GLLSN
691
VSHVI
696
VDEVH
701
ERSVQ
706
SDFLL
711
IILKE
716
ILQKR
721
SDLHL
726
ILMSA
731
TVDSE
736
KFSTY
741
FTHCP
746
ILRIS
751
GRSYP
756
VEVFH
761
LEDII
766
EETGF
771
VLEKD
776
SEYCQ
781
KFLEE
786
EEEVT
791
INVTS
796
KAGGI
801
KKYQE
806
YIPVQ
811
TGAHA
816
DLNPF
821
YQKYS
826
SRTQH
831
AILYM
836
NPHKI
841
NLDLI
846
LELLA
851
YLDKS
856
PQFRN
861
IEGAV
866
LIFLP
871
GLAHI
876
QQLYD
881
LLSND
886
RRFYS
891
ERYKV
896
IALHS
901
ILSTQ
906
DQAAA
911
FTLPP
916
PGVRK
921
IVLAT
926
NIAET
931
GITIP
936
DVVFV
941
IDTGR
946
TKENK
951
YHESS
956
QMSSL
961
VETFV
966
SKASA
971
LQRQG
976
RAGRV
981
RDGFC
986
FRMYT
991
RERFE
996
GFMDY
1001
SVPEI
1006
LRVPL
1011
EELCL
1016
HIMKC
1021
NLGSP
1026
EDFLS
1031
KALDP
1036
PQLQV
1041
ISNAM
1046
NLLRK
1051
IGACE
1056
LNEPK
1061
LTPLG
1066
QHLAA
1071
LPVNV
1076
KIGKM
1081
LIFGA
1086
IFGCL
1091
DPVAT
1096
LAAVM
1101
TEKSP
1106
FTTPI
1111
GRKDE
1116
ADLAK
1121
SALAM
1126
ADSDH
1131
LTIYN
1136
AYLGW
1141
KKARQ
1146
EGGYR
1151
SEITY
1156
CRRNF
1161
LNRTS
1166
LLTLE
1171
DVKQE
1176
LIKLV
1181
KAAGF
1186
SSSTT
1191
STSWE
1196
GNRAS
1201
QTLSF
1206
QEIAL
1211
LKAVL
1216
VAGLY
1221
DNVGK
1226
IIYTK
1231
SVDVT
1236
EKLAC
1241
IVETA
1246
QGKAQ
1251
VHPSS
1256
VNRDL
1261
QTHGW
1266
LLYQE
1271
KIRYA
1276
RVYLR
1281
ETTLI
1286
TPFPV
1291
LLFGG
1296
DIEVQ
1301
HRERL
1306
LSIDG
1311
WIYFQ
1316
APVKI
1321
AVIFK
1326
QLRVL
1331
IDSVL
1336
RKKLE
1341
NPKMS
1346
LENDK
1351
ILQII
1356
TELIK
1361
TENN
1366
Mutation Information
DNA mutation:
None
Peptide Range:
823 ~ 847
Mut AA position:
835 (13 in Wild Type peptide)
Alignment
Wild Type:
"NPFYQKYSSRTQHAILYMNPHKINL
||||||||||||.||||||||||||
Mutant:
NPFYQKYSSRTQYAILYMNPHKINL"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) DHX29

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

None

Assay

IFNg ELISPOT assay