Immunogenicity 10809
Sample ID
3678
Response
Negative
Tumor Type
Melanoma
Gene Symbol
DMRT2
Transcript ID
None
HLA INFO
A*03:01
TCR INFO
No TCR info found!
Full length protein sequence (561 aa)
MADPQ
1
AGSAA
6
GDWEI
11
DVESL
16
ELEED
21
VCGAP
26
RSTPP
31
GPSPP
36
PADGD
41
CEDDE
46
DDDGV
51
DEDAE
56
EEGDG
61
EEAGA
66
SPGMP
71
GQPEQ
76
RGGPQ
81
PRPPL
86
APQAS
91
PAGTG
96
PRERC
101
TPAGG
106
GAEPR
111
KLSRT
116
PKCAR
121
CRNHG
126
VVSCL
131
KGHKR
136
FCRWR
141
DCQCA
146
NCLLV
151
VERQR
156
VMAAQ
161
VALRR
166
QQATE
171
DKKGL
176
SGKQN
181
NFERK
186
AVYQR
191
QVRAP
196
SLLAK
201
SILEG
206
YRPIP
211
AETYV
216
GGTFP
221
LPPPV
226
SDRMR
231
KRRAF
236
ADKEL
241
ENIML
246
EREYK
251
EREML
256
ETSQA
261
AALFL
266
PNRMV
271
PGPDY
276
NSYKS
281
AYSPS
286
PVEPP
291
SKDFC
296
NFLPT
301
CLDLT
306
MQYSG
311
SGNME
316
LISSN
321
VSVAT
326
TYRQY
331
PLSSR
336
FLVWP
341
KCGPI
346
SDTLL
351
YQQCL
356
LNATT
361
SVQAL
366
KPGAS
371
WDLKG
376
ARVQD
381
GLSAE
386
QDMMP
391
SKLEG
396
SLVLP
401
HTPEI
406
QTTRS
411
DLQGH
416
QAVPE
421
RSAFS
426
PPRRN
431
FSPIV
436
DTDSL
441
AAQGH
446
VLTKI
451
SKENT
456
RHPLP
461
LRHNP
466
FHSLF
471
QQTLT
476
DKSGP
481
ELKTP
486
FVKEA
491
FEETP
496
KKHRE
501
CLVKD
506
NQKYT
511
FTIDR
516
CAKDL
521
FVAKQ
526
VGTKL
531
SVNEP
536
LSFSV
541
ESILK
546
RPSSA
551
ITRVS
556
Q
561
Mutation Information
DNA mutation:
None
Peptide Range:
403 ~ 427
Mut AA position:
415 (13 in Wild Type peptide)
Alignment
Wild Type:
"VLPHTPEIQTTRSDLQGHQAVPERS
||||||||||||.||||||||||||
Mutant:
VLPHTPEIQTTRRDLQGHQAVPERS"
Clin Cancer Res, 2017
Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 ExpressionGene Name (from Reference) DMRT2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
ELISPOT assay