Immunogenicity 10836

summary
Sample ID
3678
Response
Negative
Tumor Type
Melanoma
Gene Symbol
EP400
Transcript ID
None
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (3123 aa)
MHHGT
1
GPQNV
6
QHQLQ
11
RSRAC
16
PGSEG
21
EEQPA
26
HPNPP
31
PSPAA
36
PFAPS
41
ASPSA
46
PQSPS
51
YQIQQ
56
LMNRS
61
PATGQ
66
NVNIT
71
LQSVG
76
PVVGG
81
NQQIT
86
LAPLP
91
LPSPT
96
SPGFQ
101
FSAQP
106
RRFEH
111
GSPSY
116
IQVTS
121
PLSQQ
126
VQTQS
131
PTQPS
136
PGPGQ
141
ALQNV
146
RAGAP
151
GPGLG
156
LCSSS
161
PTGGF
166
VDASV
171
LVRQI
176
SLSPS
181
SGGHF
186
VFQDG
191
SGLTQ
196
IAQGA
201
QVQLQ
206
HPGTP
211
ITVRE
216
RRPSQ
221
PHTQS
226
GGTIH
231
HLGPQ
236
SPAAA
241
GGAGL
246
QPLAS
251
PSHIT
256
TANLP
261
PQISS
266
IIQGQ
271
LVQQQ
276
QVLQG
281
PPLPR
286
PLGFE
291
RTPGV
296
LLPGA
301
GGAAG
306
FGMTS
311
PPPPT
316
SPSRT
321
AVPPG
326
LSSLP
331
LTSVG
336
NTGMK
341
KVPKK
346
LEEIP
351
PASPE
356
MAQMR
361
KQCLD
366
YHYQE
371
MQALK
376
EVFKE
381
YLIEL
386
FFLQH
391
FQGNM
396
MDFLA
401
FKKKH
406
YAPLQ
411
AYLRQ
416
NDLDI
421
EEEEE
426
EEEEE
431
EEKSE
436
VINDE
441
QQALA
446
GSLVA
451
GAGST
456
VETDL
461
FKRQQ
466
AMPST
471
GMAEQ
476
SKRPR
481
LEVGH
486
QGVVF
491
QHPGA
496
DAGVP
501
LQQLM
506
PTAQG
511
GMPPT
516
PQAAQ
521
LAGQR
526
QSQQQ
531
YDPST
536
GPPVQ
541
NAASL
546
HTPLP
551
QLPGR
556
LPPAG
561
VPTAA
566
LSSAL
571
QFAQQ
576
PQVVE
581
AQTQL
586
QIPVK
591
TQQPN
596
VPIPA
601
PPSSQ
606
LPIPP
611
SQPAQ
616
LALHV
621
PTPGK
626
VQVQA
631
SQLSS
636
LPQMV
641
ASTRL
646
PVDPA
651
PPCPR
656
PLPTS
661
STSSL
666
APVSG
671
SGPGP
676
SPARS
681
SPVNR
686
PSSAT
691
NKALS
696
PVTSR
701
TPGVV
706
ASAPT
711
KPQSP
716
AQNAT
721
SSQDS
726
SQDTL
731
TEQIT
736
LENQV
741
HQRIA
746
ELRKA
751
GLWSQ
756
RRLPK
761
LQEAP
766
RPKSH
771
WDYLL
776
EEMQW
781
MATDF
786
AQERR
791
WKVAA
796
AKKLV
801
RTVVR
806
HHEEK
811
QLREE
816
RGKKE
821
EQSRL
826
RRIAA
831
STARE
836
IECFW
841
SNIEQ
846
VVEIK
851
LRVEL
856
EEKRK
861
KALNL
866
QKVSR
871
RGKEL
876
RPKGF
881
DALQE
886
SSLDS
891
GMSGR
896
KRKAS
901
ISLTD
906
DEVDD
911
EEETI
916
EEEEA
921
NEGVV
926
DHQTE
931
LSNLA
936
KEAEL
941
PLLDL
946
MKLYE
951
GAFLP
956
SSQWP
961
RPKPD
966
GEDTS
971
GEEDA
976
DDCPG
981
DRESR
986
KDLVL
991
IDSLF
996
IMDQF
1001
KAAER
1006
MNIGK
1011
PNAKD
1016
IADVT
1021
AVAEA
1026
ILPKG
1031
SARVT
1036
TSVKF
1041
NAPSL
1046
LYGAL
1051
RDYQK
1056
IGLDW
1061
LAKLY
1066
RKNLN
1071
GILAD
1076
EAGLG
1081
KTVQI
1086
IAFFA
1091
HLACN
1096
EGNWG
1101
PHLVV
1106
VRSCN
1111
ILKWE
1116
LELKR
1121
WCPGL
1126
KILSY
1131
IGSHR
1136
ELKAK
1141
RQEWA
1146
EPNSF
1151
HVCIT
1156
SYTQF
1161
FRGLT
1166
AFTRV
1171
RWKCL
1176
VIDEM
1181
QRVKG
1186
MTERH
1191
WEAVF
1196
TLQSQ
1201
QRLLL
1206
IDSPL
1211
HNTFL
1216
ELWTM
1221
VHFLV
1226
PGISR
1231
PYLSS
1236
PLRAP
1241
SEESQ
1246
DYYHK
1251
VVIRL
1256
HRVTQ
1261
PFILR
1266
RTKRD
1271
VEKQL
1276
TKKYE
1281
HVLKC
1286
RLSNR
1291
QKALY
1296
EDVIL
1301
QPGTQ
1306
EALKS
1311
GHFVN
1316
VLSIL
1321
VRLQR
1326
ICNHP
1331
GLVEP
1336
RHPGS
1341
SYVAG
1346
PLEYP
1351
SASLI
1356
LKALE
1361
RDFWK
1366
EADLS
1371
MFDLI
1376
GLENK
1381
ITRHE
1386
AELLS
1391
KKKIP
1396
RKLME
1401
EISTS
1406
AAPAA
1411
RPAAA
1416
KLKAS
1421
RLFQP
1426
VQYGQ
1431
KPEGR
1436
TVAFP
1441
STHPP
1446
RTAAP
1451
TTASA
1456
APQGP
1461
LRGRP
1466
PIATF
1471
SANPE
1476
AKAAA
1481
APFQT
1486
SQASA
1491
SAPRH
1496
QPASA
1501
SSTAA
1506
SPAHP
1511
AKLRA
1516
QTTAQ
1521
ASTPG
1526
QPPPQ
1531
PQAPS
1536
HAAGQ
1541
SALPQ
1546
RLVLP
1551
SQAQA
1556
RLPSG
1561
EVVKI
1566
AQLAS
1571
ITGPQ
1576
SRVAQ
1581
PETPV
1586
TLQFQ
1591
GSKFT
1596
LSHSQ
1601
LRQLT
1606
AGQPL
1611
QLQGS
1616
VLQIV
1621
SAPGQ
1626
PYLRA
1631
PGPVV
1636
MQTVS
1641
QAGAV
1646
HGALG
1651
SKPPA
1656
GGPSP
1661
APLTP
1666
QVGVP
1671
GRVAV
1676
NALAV
1681
GEPGT
1686
ASKPA
1691
SPIGG
1696
PTQEE
1701
KTRLL
1706
KERLD
1711
QIYLV
1716
NERRC
1721
SQAPV
1726
YGRDL
1731
LRICA
1736
LPSHG
1741
RVQWR
1746
GSLDG
1751
RRGKE
1756
AGPAH
1761
SYTSS
1766
SESPS
1771
ELMLT
1776
LCRCG
1781
ESLQD
1786
VIDRV
1791
AFVIP
1796
PVVAA
1801
PPSLR
1806
VPRPP
1811
PLYSH
1816
RMRIL
1821
RQGLR
1826
EHAAP
1831
YFQQL
1836
RQTTA
1841
PRLLQ
1846
FPELR
1851
LVQFD
1856
SGKLE
1861
ALAIL
1866
LQKLK
1871
SEGRR
1876
VLILS
1881
QMILM
1886
LDILE
1891
MFLNF
1896
HYLTY
1901
VRIDE
1906
NASSE
1911
QRQEL
1916
MRSFN
1921
RDRRI
1926
FCAIL
1931
STHSR
1936
TTGIN
1941
LVEAD
1946
TVVFY
1951
DNDLN
1956
PVMDA
1961
KAQEW
1966
CDRIG
1971
RCKDI
1976
HIYRL
1981
VSGNS
1986
IEEKL
1991
LKNGT
1996
KDLIR
2001
EVAAQ
2006
GNDYS
2011
MAFLT
2016
QRTIQ
2021
ELFEV
2026
YSPMD
2031
DAGFP
2036
VKAEE
2041
FVVLS
2046
QEPSV
2051
TETIA
2056
PKIAR
2061
PFIEA
2066
LKSIE
2071
YLEED
2076
AQKSA
2081
QEGVL
2086
GPHTD
2091
ALSSD
2096
SENMP
2101
CDEEP
2106
SQLEE
2111
LADFM
2116
EQLTP
2121
IEKYA
2126
LNYLE
2131
LFHTS
2136
IEQEK
2141
ERNSE
2146
DAVMT
2151
AVRAW
2156
EFWNL
2161
KTLQE
2166
REARL
2171
RLEQE
2176
EAELL
2181
TYTRE
2186
DAYSM
2191
EYVYE
2196
DVDGQ
2201
TEVMP
2206
LWTPP
2211
TPPQD
2216
DSDIY
2221
LDSVM
2226
CLMYE
2231
ATPIP
2236
EAKLP
2241
PVYVR
2246
KERKR
2251
HKTDP
2256
SAAGR
2261
KKKQR
2266
HGEAV
2271
VPPRS
2276
LFDRA
2281
TPGLL
2286
KIRRE
2291
GKEQK
2296
KNILL
2301
KQQVP
2306
FAKPL
2311
PTFAK
2316
PTAEP
2321
GQDNP
2326
EWLIS
2331
EDWAL
2336
LQAVK
2341
QLLEL
2346
PLNLT
2351
IVSPA
2356
HTPNW
2361
DLVSD
2366
VVNSC
2371
SRIYR
2376
SSKQC
2381
RNRYE
2386
NVIIP
2391
REEGK
2396
SKNNR
2401
PLRTS
2406
QIYAQ
2411
DENAT
2416
HTQLY
2421
TSHFD
2426
LMKMT
2431
AGKRS
2436
PPIKP
2441
LLGMN
2446
PFQKN
2451
PKHAS
2456
VLAES
2461
GINYD
2466
KPLPP
2471
IQVAS
2476
LRAER
2481
IAKEK
2486
KALAD
2491
QQKAQ
2496
QPAVA
2501
QPPPP
2506
QPQPP
2511
PPPQQ
2516
PPPPL
2521
PQPQA
2526
AGSQP
2531
PAGPP
2536
AVQPQ
2541
PQPQP
2546
QTQPQ
2551
PVQAP
2556
AKAQP
2561
AITTG
2566
GSAAV
2571
LAGTI
2576
KTSVT
2581
GTSMP
2586
TGAVS
2591
GNVIV
2596
NTIAG
2601
VPAAT
2606
FQSIN
2611
KRLAS
2616
PVAPG
2621
ALTTP
2626
GGSAP
2631
AQVVH
2636
TQPPP
2641
RAVGS
2646
PATAT
2651
PDLVS
2656
MATTQ
2661
GVRAV
2666
TSVTA
2671
SAVVT
2676
TNLTP
2681
VQTPA
2686
RSLVP
2691
QVSQA
2696
TGVQL
2701
PGKTI
2706
TPAHF
2711
QLLRQ
2716
QQQQQ
2721
QQQQQ
2726
QQQQQ
2731
QQQQQ
2736
QQQQQ
2741
QQQTT
2746
TTSQV
2751
QVPQI
2756
QGQAQ
2761
SPAQI
2766
KAVGK
2771
LTPEH
2776
LIKMQ
2781
KQKLQ
2786
MPPQP
2791
PPPQA
2796
QSAPP
2801
QPTAQ
2806
VQVQT
2811
SQPPQ
2816
QQSPQ
2821
LTTVT
2826
APRPG
2831
ALLTG
2836
TTVAN
2841
LQVAR
2846
LTRVP
2851
TSQLQ
2856
AQGQM
2861
QTQAP
2866
QPAQV
2871
ALAKP
2876
PVVSV
2881
PAAVV
2886
SSPGV
2891
TTLPM
2896
NVAGI
2901
SVAIG
2906
QPQKA
2911
AGQTV
2916
VAQPV
2921
HMQQL
2926
LKLKQ
2931
QAVQQ
2936
QKAIQ
2941
PQAAQ
2946
GPAAV
2951
QQKIT
2956
AQQIT
2961
TPGAQ
2966
QKVAY
2971
AAQPA
2976
LKTQF
2981
LTTPI
2986
SQAQK
2991
LAGAQ
2996
QVQTQ
3001
IQVAK
3006
LPQVV
3011
QQQTP
3016
VASIQ
3021
QVASA
3026
SQQAS
3031
PQTVA
3036
LTQAT
3041
AAGQQ
3046
VQMIP
3051
AVTAT
3056
AQVVQ
3061
QKLIQ
3066
QQVVT
3071
TASAP
3076
LQTPG
3081
APNPA
3086
QVPAS
3091
SDSPS
3096
QQPKL
3101
QMRVP
3106
AVRLK
3111
TPTKP
3116
PCQ
3121
Mutation Information
DNA mutation:
None
Peptide Range:
806 ~ 830
Mut AA position:
818 (13 in Wild Type peptide)
Alignment
Wild Type:
"RTVVRHHEEKQLREERGKKEEQSRL
||||||||||||.||||||||||||
Mutant:
RTVVRHHEEKQLCEERGKKEEQSRL"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

ELISPOT assay