Immunogenicity 10851

summary
Sample ID
3678
Response
Negative
Tumor Type
Melanoma
Gene Symbol
FRAS1
Transcript ID
None
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (3936 aa)
MGVLK
1
VWLGL
6
ALALA
11
EFAVL
16
PHHSE
21
GACVY
26
QDSLL
31
ADATI
36
WKPDS
41
CQSCR
46
CHGDI
51
VICKP
56
AVCRN
61
PQCAF
66
EKGEV
71
LQIAA
76
NQCCP
81
ECVLR
86
TPGSC
91
HHEKK
96
IHEHG
101
TEWAS
106
SPCSV
111
CSCNH
116
GEVRC
121
TPQPC
126
PPLSC
131
GHQEL
136
AFIPE
141
GSCCP
146
VCVGL
151
GKPCS
156
YEGHV
161
FQDGE
166
DWRLS
171
RCAKC
176
LCRNG
181
VAQCF
186
TAQCQ
191
PLFCN
196
QDETV
201
VRVPG
206
KCCPQ
211
CSARS
216
CSAAG
221
QVYEH
226
GEQWS
231
ENACT
236
TCICD
241
RGEVR
246
CHKQA
251
CLPLR
256
CGKGQ
261
SRARR
266
HGQCC
271
EECVS
276
PAGSC
281
SYDGV
286
VRYQD
291
EMWKG
296
SACEF
301
CMCDH
306
GQVTC
311
QTGEC
316
AKVEC
321
ARDEE
326
LIHLD
331
GKCCP
336
ECISR
341
NGYCV
346
YEETG
351
EFMSS
356
NASEV
361
KRIPE
366
GEKWE
371
DGPCK
376
VCECR
381
GAQVT
386
CYEPS
391
CPPCP
396
VGTLA
401
LEVKG
406
QCCPD
411
CTSVH
416
CHPDC
421
LTCSQ
426
SPDHC
431
DLCQD
436
PTKLL
441
QNGWC
446
VHSCG
451
LGFYQ
456
AGSLC
461
LACQP
466
QCSTC
471
TSGLE
476
CSSCQ
481
PPLLM
486
RHGQC
491
VPTCG
496
DGFYQ
501
DRHSC
506
AVCHE
511
SCAGC
516
WGPTE
521
KHCLA
526
CRDPL
531
HVLRD
536
GGCES
541
SCGKG
546
FYNRQ
551
GTCSA
556
CDQSC
561
DSCGP
566
SSPRC
571
LTCTE
576
KTVLH
581
DGKCM
586
SECPG
591
GYYAD
596
ATGRC
601
KVCHN
606
SCASC
611
SGPTP
616
SHCTA
621
CSPPK
626
ALRQG
631
HCLPR
636
CGEGF
641
YSDHG
646
VCKAC
651
HSSCL
656
ACMGP
661
APSHC
666
TGCKK
671
PEEGL
676
QVEQL
681
SDVGI
686
PSGEC
691
LAQCR
696
AHFYL
701
ESTGI
706
CEACH
711
QSCFR
716
CAGKS
721
PHNCT
726
DCGPS
731
HVLLD
736
GQCLS
741
QCPDG
746
YFHQE
751
GSCTE
756
CHPTC
761
RQCHG
766
PLESD
771
CISCY
776
PHISL
781
TNGNC
786
RTSCR
791
EEQFL
796
NLVGY
801
CADCH
806
HLCQH
811
CAADL
816
HNTGS
821
ICLRC
826
QNAHY
831
LLLGD
836
HCVPD
841
CPSGY
846
YAERG
851
ACKKC
856
HSSCR
861
TCQGR
866
GPFSC
871
SSCDT
876
NLVLS
881
HTGTC
886
STTCF
891
PGHYL
896
DDNHV
901
CQPCN
906
THCGS
911
CDSQA
916
SCTSC
921
RDPNK
926
VLLFG
931
ECQYE
936
SCAPQ
941
YYLDF
946
STNTC
951
KECDW
956
SCSAC
961
SGPLK
966
TDCLQ
971
CMDGY
976
VLQDG
981
ACVEQ
986
CLSSF
991
YQDSG
996
LCKNC
1001
DSYCL
1006
QCQGP
1011
HECTR
1016
CKGPF
1021
LLLEA
1026
QCVQE
1031
CGKGY
1036
FADHA
1041
KHKCT
1046
ACPQG
1051
CLQCS
1056
HRDRC
1061
HLCDH
1066
GFFLK
1071
SGLCV
1076
YNCVP
1081
GFSVH
1086
TSNET
1091
CSGKI
1096
HTPSL
1101
HVNGS
1106
LILPI
1111
GSIKP
1116
LDFSL
1121
LNVQD
1126
QEGRV
1131
EDLLF
1136
HVVST
1141
PTNGQ
1146
LVLSR
1151
NGKEV
1156
QLDKA
1161
GRFSW
1166
KDVNE
1171
KKVRF
1176
VHSKE
1181
KLRKG
1186
YLFLK
1191
ISDQQ
1196
FFSEP
1201
QLINI
1206
QAFST
1211
QAPYV
1216
LRNEV
1221
LHISR
1226
GERAT
1231
ITTQM
1236
LDIRD
1241
DDNPQ
1246
DVVIE
1251
IIDPP
1256
LHGQL
1261
LQTLQ
1266
SPATP
1271
IYQFQ
1276
LDELS
1281
RGLLH
1286
YAHDG
1291
SDSTS
1296
DVAVL
1301
QANDG
1306
HSFHN
1311
ILFQV
1316
KTVPQ
1321
NDRGL
1326
QLVAN
1331
SMVWV
1336
PEGGM
1341
LQITN
1346
RILQA
1351
EAPGA
1356
SAEEI
1361
IYKIT
1366
QDYPQ
1371
FGEVV
1376
LLVNM
1381
PADSP
1386
ADEGQ
1391
HLPDG
1396
RTATP
1401
TSTFT
1406
QQDIN
1411
EGIVW
1416
YRHSG
1421
APAQS
1426
DSFRF
1431
EVSSA
1436
SNAQT
1441
RLESH
1446
MFNIA
1451
ILPQT
1456
PEAPK
1461
VSLEA
1466
SLHMT
1471
AREDG
1476
LTVIQ
1481
PHSLS
1486
FINSE
1491
KPSGK
1496
IVYNI
1501
TLPLH
1506
PNQGI
1511
IEHRD
1516
HPHSP
1521
IRYFT
1526
QEDIN
1531
QGKVM
1536
YRPPP
1541
AAPHL
1546
QELMA
1551
FSFAG
1556
LPESV
1561
KFHFT
1566
VSDGE
1571
HTSPE
1576
MVLTI
1581
HLLPS
1586
DQQLP
1591
VFQVT
1596
APRLA
1601
VSPGG
1606
STSVG
1611
LQVVV
1616
RDAET
1621
APKEL
1626
FFELR
1631
RPPQH
1636
GVLLK
1641
HTAEF
1646
RRPMA
1651
TGDTF
1656
TYEDV
1661
EKNAL
1666
QYIHD
1671
GSSTR
1676
EDSME
1681
ISVTD
1686
GLTVT
1691
MLEVR
1696
VEVSL
1701
SEDRG
1706
PRLAA
1711
GSSLS
1716
ITVAS
1721
KSTAI
1726
ITRSH
1731
LAYVD
1736
DSSPD
1741
PEIWI
1746
QLNYL
1751
PSYGT
1756
LLRIS
1761
GSEVE
1766
ELSEV
1771
SNFTM
1776
EDINN
1781
KKIRY
1786
SAVFE
1791
TDGHL
1796
VTDSF
1801
YFSVS
1806
DMDHN
1811
HLDNQ
1816
IFTIM
1821
ITPAE
1826
NPPPV
1831
IAFAD
1836
LITVD
1841
EGGRA
1846
PLSFH
1851
HFFAT
1856
DDDDN
1861
LQRDA
1866
IIKLS
1871
ALPKY
1876
GCIEN
1881
TGTGD
1886
RFGPE
1891
TASDL
1896
EASFP
1901
IQDVL
1906
ENYIY
1911
YFQSV
1916
HESIE
1921
PTHDI
1926
FSFYV
1931
SDGTS
1936
RSEIH
1941
SINIT
1946
IERKN
1951
DEPPR
1956
MTLQP
1961
LRVQL
1966
SSGVV
1971
ISNSS
1976
LSLQD
1981
LDTPD
1986
NELIF
1991
VLTKK
1996
PDHGH
2001
VLWRQ
2006
TASEP
2011
LENGR
2016
VLVQG
2021
STFTY
2026
QDILA
2031
GLVGY
2036
VPSVP
2041
GMVVD
2046
EFQFS
2051
LTDGL
2056
HVDTG
2061
RMKIY
2066
TELPA
2071
SDTPH
2076
LAINQ
2081
GLQLS
2086
AGSVA
2091
RITEQ
2096
HLKVT
2101
DIDSD
2106
DHQVM
2111
YIMKE
2116
DPGAG
2121
RLQMM
2126
KHGNL
2131
EQISI
2136
KGPIR
2141
SFTQA
2146
DISQG
2151
HVEYS
2156
HGTGE
2161
PGGSF
2166
AFKFD
2171
VVDGE
2176
GNRLI
2181
DKSFS
2186
ISILE
2191
DKSPP
2196
VITTN
2201
KGLVL
2206
DENSV
2211
KKITT
2216
LQLSA
2221
TDQDS
2226
GPTEL
2231
IYRIT
2236
RQPQL
2241
GHLEH
2246
AASPG
2251
IQISS
2256
FTQAD
2261
LTSRN
2266
VQYVH
2271
SSEAE
2276
KHSDA
2281
FSFTL
2286
SDGVS
2291
EVTQT
2296
FHITL
2301
HPVDD
2306
SLPVV
2311
QNLGM
2316
RVQEG
2321
MRKTI
2326
TEFEL
2331
KAVDA
2336
DTEIM
2341
TAAPQ
2346
PFRVD
2351
ILPVD
2356
DGTPR
2361
IVTNL
2366
GLQWL
2371
EYMDG
2376
KATNL
2381
ITKKE
2386
LLTMD
2391
PDTED
2396
AQLVY
2401
EITTG
2406
PKHGF
2411
VENKL
2416
QPGRA
2421
AATFT
2426
QEDVN
2431
LGLIR
2436
YVLHK
2441
EKIRE
2446
MMDSF
2451
QFLVK
2456
DSKPN
2461
VVSDN
2466
VFHIQ
2471
WSLIS
2476
FKYTS
2481
YNVSE
2486
KAGSV
2491
SVTVQ
2496
RTGNL
2501
NQYAI
2506
VLCRT
2511
EQGTA
2516
SSSSR
2521
VSSQP
2526
GQQDY
2531
VEYAG
2536
QVQFD
2541
EREDT
2546
KSCTI
2551
VINDD
2556
DVFEN
2561
VESFT
2566
VELSM
2571
PAYAL
2576
LGEFT
2581
QAKVI
2586
INDTE
2591
DEPTL
2596
EFDKK
2601
IYWVN
2606
ESAGF
2611
LFAPI
2616
ERKGD
2621
ASSIV
2626
SAICY
2631
TVPKS
2636
AMGSS
2641
LYALE
2646
SGSDF
2651
KSRGM
2656
SAASR
2661
VIFGP
2666
GVTMS
2671
TCDVM
2676
LIDDS
2681
EYEEE
2686
EEFEI
2691
ALADA
2696
SDNAR
2701
IGRVA
2706
TAKVL
2711
ISGPN
2716
DASTV
2721
SLGNT
2726
AFTVS
2731
EDAGT
2736
VKIPV
2741
IRHGT
2746
DLSTF
2751
ASVWC
2756
ATRPS
2761
DPASA
2766
TPGVD
2771
YVPSS
2776
RKVEF
2781
GPGVI
2786
EQYCT
2791
LTILD
2796
DTQYP
2801
VIEGL
2806
ETFVV
2811
FLSSA
2816
QGAEL
2821
TKPFQ
2826
AVIAI
2831
NDTFQ
2836
DVPSM
2841
QFAKD
2846
LLLVK
2851
EKEGV
2856
LHVPI
2861
TRSGD
2866
LSYES
2871
SVRCY
2876
TQSHS
2881
AQVME
2886
DFEER
2891
QNADS
2896
SRITF
2901
LKGDK
2906
VKNCT
2911
VYIHD
2916
DSMFE
2921
PEEQF
2926
RVYLG
2931
LPLGN
2936
HWSGA
2941
RIGKN
2946
NMATI
2951
TISND
2956
EDAPT
2961
IEFEE
2966
AAYQV
2971
REPAG
2976
PDAIA
2981
ILNIK
2986
VIRRG
2991
DQNRT
2996
SKVRC
3001
STRDG
3006
SAQSG
3011
VDYYP
3016
KSRVL
3021
KFSPG
3026
VDHIF
3031
FKVEI
3036
LSNED
3041
REWHE
3046
SFSLV
3051
LGPDD
3056
PVEAV
3061
LGDVT
3066
TATVT
3071
ILDQE
3076
AAGSL
3081
ILPAP
3086
PIVVT
3091
LADYD
3096
HVEEV
3101
TKEGV
3106
KKSPS
3111
PGYPL
3116
VCVTP
3121
CDPHF
3126
PRYAV
3131
MKERC
3136
SEAGI
3141
NQTSV
3146
QFSWE
3151
VAAPT
3156
DGNGA
3161
RSPFE
3166
TITDN
3171
TPFTS
3176
VNHMV
3181
LDSIY
3186
FSRRF
3191
HVRCV
3196
AKAVD
3201
KVGHV
3206
GTPLR
3211
SNIVT
3216
IGTDS
3221
AICHT
3226
PVVAG
3231
TSRGF
3236
QAQSF
3241
IATLK
3246
YLDVK
3251
HKEHP
3256
NRIHI
3261
SVQIP
3266
HQDGM
3271
LPLIS
3276
TMPLH
3281
NLHFL
3286
LSESI
3291
YRHQH
3296
VCSNL
3301
VTTYD
3306
LRGIS
3311
EAGFL
3316
DDVVY
3321
DSTAL
3326
GPGYD
3331
RPFQF
3336
DPSVR
3341
EPKTI
3346
QLYKH
3351
LNLKS
3356
CVWTF
3361
DAYYD
3366
MTELI
3371
DVCGG
3376
SVTAD
3381
FQVRD
3386
SAQSF
3391
LTVHV
3396
PLYVS
3401
YIYVT
3406
APRGW
3411
ASLEH
3416
HTEME
3421
FSFFY
3426
DTVLW
3431
RTGIQ
3436
TDSVL
3441
SARLQ
3446
IIRIY
3451
IREDG
3456
RLVIE
3461
FKTHA
3466
KFRGQ
3471
FVMEH
3476
HTLPE
3481
VKSFV
3486
LTPDH
3491
LGGIE
3496
FDLQL
3501
LWSAQ
3506
TFDSP
3511
HQLWR
3516
ATSSY
3521
NRKDY
3526
SGEYT
3531
IYLIP
3536
CTVQP
3541
TQPWV
3546
DPGEK
3551
PLACT
3556
AHAPE
3561
RFLIP
3566
IAFQQ
3571
TNRPV
3576
PVVYS
3581
LNTEF
3586
QLCNN
3591
EKVFL
3596
MDPNT
3601
SDMSL
3606
AEMDY
3611
KGAFS
3616
KGQIL
3621
YGRVL
3626
WNPEQ
3631
NLNSA
3636
YKLQL
3641
EKVYL
3646
CTGKD
3651
GYVPF
3656
FDPTG
3661
TIYNE
3666
GPQYG
3671
CIQPN
3676
KHLKH
3681
RFLLL
3686
DRNQP
3691
EVTDK
3696
YFHDV
3701
PFEAH
3706
FASEL
3711
PDFHV
3716
VSNMP
3721
GVDGF
3726
TLKVD
3731
ALYKV
3736
EAGHQ
3741
WYLQV
3746
IYIIG
3751
PDTIS
3756
GPRVQ
3761
RSLTA
3766
PLRRN
3771
RRDLV
3776
EPDGQ
3781
LILDD
3786
SLIYD
3791
NEGDQ
3796
VKNGT
3801
NMKSL
3806
NLEMQ
3811
ELAVA
3816
ASLSQ
3821
TGASI
3826
GSALA
3831
AIMLL
3836
LLVFL
3841
VACFI
3846
NRKCQ
3851
KQRKK
3856
KPAED
3861
ILEEY
3866
PLNTK
3871
VEVPK
3876
RHPDR
3881
VEKNV
3886
NRHYC
3891
TVRNV
3896
NILSE
3901
PEAAY
3906
TFKGA
3911
KVKRL
3916
NLEVR
3921
VHNNL
3926
QDGTE
3931
V
3936
Mutation Information
DNA mutation:
None
Peptide Range:
1551 ~ 1575
Mut AA position:
1563 (13 in Wild Type peptide)
Alignment
Wild Type:
"QELMAFSFAGLPESVKFHFTVSDGE
||||||||||||.||||||||||||
Mutant:
QELMAFSFAGLPKSVKFHFTVSDGE"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

ELISPOT assay