Immunogenicity 10869

summary
Sample ID
3678
Response
Negative
Tumor Type
Melanoma
Gene Symbol
HELZ
Transcript ID
None
HLA INFO
C*14:02
TCR INFO

No TCR info found!

T cell Tumor cell C*14:02
sequence
Full length protein sequence (1942 aa)
MEDRR
1
AEKSC
6
EQACE
11
SLKRQ
16
DYEMA
21
LKHCT
26
EALLS
31
LGQYS
36
MADFT
41
GPCPL
46
EIERI
51
KIESL
56
LYRIA
61
SFLQL
66
KNYVQ
71
ADEDC
76
RHVLG
81
EGLAK
86
GEDAF
91
RAVLC
96
CMQLK
101
GKLQP
106
VSTIL
111
AKSLT
116
GESLN
121
GMVTK
126
DLTRL
131
KTLLS
136
ETETA
141
TSNAL
146
SGYHV
151
EDLDE
156
GSCNG
161
WHFRP
166
PPRGI
171
TSSEE
176
YTLCK
181
RFLEQ
186
GICRY
191
GAQCT
196
SAHSQ
201
EELAE
206
WQKRY
211
ASRLI
216
KLKQQ
221
NENKQ
226
LSGSY
231
METLI
236
EKWMN
241
SLSPE
246
KVLSE
251
CIEGV
256
KVEHN
261
PDLSV
266
TVSTK
271
KSHQT
276
WTFAL
281
TCKPA
286
RMLYR
291
VALLY
296
DAHRP
301
HFSII
306
AISAG
311
DSTTQ
316
VSQEV
321
PENCQ
326
EWIGG
331
KMAQN
336
GLDHY
341
VYKVG
346
IAFNT
351
EIFGT
356
FRQTI
361
VFDFG
366
LEPVL
371
MQRVM
376
IDAAS
381
TEDLE
386
YLMHA
391
KQQLV
396
TTAKR
401
WDSSS
406
KTIID
411
FEPNE
416
TTDLE
421
KSLLI
426
RYQIP
431
LSADQ
436
LFTQS
441
VLDKS
446
LTKSN
451
YQSRL
456
HDLLY
461
IEEIA
466
QYKEI
471
SKFNL
476
KVQLQ
481
ILASF
486
MLTGV
491
SGGAK
496
YAQNG
501
QLFGR
506
FKLTE
511
TLSED
516
TLAGR
521
LVMTK
526
VNAVY
531
LLPVP
536
KQKLV
541
QTQGT
546
KEKVY
551
EATIE
556
EKTKE
561
YIFLR
566
LSREC
571
CEELN
576
LRPDC
581
DTQVE
586
LQFQL
591
NRLPL
596
CEMHY
601
ALDRI
606
KDNGV
611
LFPDI
616
SMTPT
621
IPWSP
626
NRQWD
631
EQLDP
636
RLNAK
641
QKEAV
646
LAITT
651
PLAIQ
656
LPPVL
661
IIGPY
666
GTGKT
671
FTLAQ
676
AVKHI
681
LQQQE
686
TRILI
691
CTHSN
696
SAADL
701
YIKDY
706
LHPYV
711
EAGNP
716
QARPL
721
RVYFR
726
NRWVK
731
TVHPV
736
VHQYC
741
LISSA
746
HSTFQ
751
MPQKE
756
DILKH
761
RVVVV
766
TLNTS
771
QYLCQ
776
LDLEP
781
GFFTH
786
ILLDE
791
AAQAM
796
ECETI
801
MPLAL
806
ATQNT
811
RIVLA
816
GDHMQ
821
LSPFV
826
YSEFA
831
RERNL
836
HVSLL
841
DRLYE
846
HYPAE
851
FPCRI
856
LLCEN
861
YRSHE
866
AIINY
871
TSELF
876
YEGKL
881
MASGK
886
QPAHK
891
DFYPL
896
TFFTA
901
RGEDV
906
QEKNS
911
TAFYN
916
NAEVF
921
EVVER
926
VEELR
931
RKWPV
936
AWGKL
941
DDGSI
946
GVVTP
951
YADQV
956
FRIRA
961
ELRKK
966
RLSDV
971
NVERV
976
LNVQG
981
KQFRV
986
LFLST
991
VRTRH
996
TCKHK
1001
QTPIK
1006
KKEQL
1011
LEDST
1016
EDLDY
1021
GFLSN
1026
YKLLN
1031
TAITR
1036
AQSLV
1041
AVVGD
1046
PIALC
1051
SIGRC
1056
RKFWE
1061
RFIAL
1066
CHENS
1071
SLHGI
1076
TFEQI
1081
KAQLE
1086
ALELK
1091
KTYVL
1096
NPLAP
1101
EFIPR
1106
ALRLQ
1111
HSGST
1116
NKQQQ
1121
SPPKG
1126
KSLHH
1131
TQNDH
1136
FQNDG
1141
IVQPN
1146
PSVLI
1151
GNPIR
1156
AYTPP
1161
PPLGP
1166
HPNLG
1171
KSPSP
1176
VQRID
1181
PHTGT
1186
SILYV
1191
PAVYG
1196
GNVVM
1201
SVPLP
1206
VPWTG
1211
YQGRF
1216
AVDPR
1221
IITHQ
1226
AAMAY
1231
NMNLL
1236
QTHGR
1241
GSPIP
1246
YGLGH
1251
HPPVT
1256
IGQPQ
1261
NQHQE
1266
KDQHE
1271
QNRNG
1276
KSDTN
1281
NSGPE
1286
INKIR
1291
TPEKK
1296
PTEPK
1301
QVDLE
1306
SNPQN
1311
RSPES
1316
RPSVV
1321
YPSTK
1326
FPRKD
1331
NLNPR
1336
HINLP
1341
LPAPH
1346
AQYAI
1351
PNRHF
1356
HPLPQ
1361
LPRPP
1366
FPIPQ
1371
QHTLL
1376
NQQQN
1381
NLPEQ
1386
PNQIP
1391
PQPNQ
1396
VVQQQ
1401
SQLNQ
1406
QPQQP
1411
PPQLS
1416
PAYQA
1421
GPNNA
1426
FFNSA
1431
VAHRP
1436
QSPPA
1441
EAVIP
1446
EQQPP
1451
PMLQE
1456
GHSPL
1461
RAIAQ
1466
PGPIL
1471
PSHLN
1476
SFIDE
1481
NPSGL
1486
PIGEA
1491
LDRIH
1496
GSVAL
1501
ETLRQ
1506
QQARF
1511
QQWSE
1516
HHAFL
1521
SQGSV
1526
PYPHH
1531
HHPHL
1536
QHLPQ
1541
PPLGL
1546
HQPPV
1551
RADWK
1556
LTSSA
1561
EDEVE
1566
TTYSR
1571
FQDLI
1576
RELSH
1581
RDQSE
1586
TRELA
1591
EMPPP
1596
QSRLL
1601
QYRQV
1606
QSRSP
1611
PAVPS
1616
PPSST
1621
DHSSH
1626
FSNFN
1631
DNSRD
1636
IEVAS
1641
NPAFP
1646
QRLPP
1651
QIFNS
1656
PFSLP
1661
SEHLA
1666
PPPLK
1671
YLAPD
1676
GAWTF
1681
ANLQQ
1686
NHLMG
1691
PGFPY
1696
GLPPL
1701
PHRPP
1706
QNPFV
1711
QIQNH
1716
QHAIG
1721
QEPFH
1726
PLSSR
1731
TVSSS
1736
SLPSL
1741
EEYEP
1746
RGPGR
1751
PLYQR
1756
RISSS
1761
SVQPC
1766
SEEVS
1771
TPQDS
1776
LAQCK
1781
ELQDH
1786
SNQSS
1791
FNFSS
1796
PESWV
1801
NTTSS
1806
TPYQN
1811
IPCNG
1816
SSRTA
1821
QPREL
1826
IAPPK
1831
TVKPP
1836
EDQLK
1841
SENLE
1846
VSSSF
1851
NYSVL
1856
QHLGQ
1861
FPPLM
1866
PNKQI
1871
AESAN
1876
SSSPQ
1881
SSAGG
1886
KPAMS
1891
YASAL
1896
RAPPK
1901
PRPPP
1906
EQAKK
1911
SSDPL
1916
SLFQE
1921
LSLGS
1926
SSGSN
1931
GFYSY
1936
FK
1941
Mutation Information
DNA mutation:
None
Peptide Range:
523 ~ 547
Mut AA position:
535 (13 in Wild Type peptide)
Alignment
Wild Type:
"AGRLVMTKVNAVYLLPVPKQKLVQT
||||||||||||.||||||||||||
Mutant:
AGRLVMTKVNAVILLPVPKQKLVQT"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

ELISPOT assay