Immunogenicity 10908
Sample ID
3678
Response
Negative
Tumor Type
Melanoma
Gene Symbol
LRRC8B
Transcript ID
None
HLA INFO
A*03:01
TCR INFO
No TCR info found!
Full length protein sequence (803 aa)
MITLT
1
ELKCL
6
ADAQS
11
SYHIL
16
KPWWD
21
VFWYY
26
ITLIM
31
LLVAV
36
LAGAL
41
QLTQS
46
RVLCC
51
LPCKV
56
EFDNH
61
CAVPW
66
DILKA
71
SMNTS
76
SNPGT
81
PLPLP
86
LRIQN
91
DLHRQ
96
QYSYI
101
DAVCY
106
EKQLH
111
WFAKF
116
FPYLV
121
LLHTL
126
IFAAC
131
SNFWL
136
HYPST
141
SSRLE
146
HFVAI
151
LHKCF
156
DSPWT
161
TRALS
166
ETVAE
171
QSVRP
176
LKLSK
181
SKILL
186
SSSGC
191
SADID
196
SGKQS
201
LPYPQ
206
PGLES
211
AGIES
216
PTSSV
221
LDKKE
226
GEQAK
231
AIFEK
236
VKRFR
241
MHVEQ
246
KDIIY
251
RVYLK
256
QIIVK
261
VILFV
266
LIITY
271
VPYFL
276
THITL
281
EIDCS
286
VDVQA
291
FTGYK
296
RYQCV
301
YSLAE
306
IFKVL
311
ASFYV
316
ILVIL
321
YGLTS
326
SYSLW
331
WMLRS
336
SLKQY
341
SFEAL
346
REKSN
351
YSDIP
356
DVKND
361
FAFIL
366
HLADQ
371
YDPLY
376
SKRFS
381
IFLSE
386
VSENK
391
LKQIN
396
LNNEW
401
TVEKL
406
KSKLV
411
KNAQD
416
KIELH
421
LFMLN
426
GLPDN
431
VFELT
436
EMEVL
441
SLELI
446
PEVKL
451
PSAVS
456
QLVNL
461
KELRV
466
YHSSL
471
VVDHP
476
ALAFL
481
EENLK
486
ILRLK
491
FTEMG
496
KIPRW
501
VFHLK
506
NLKEL
511
YLSGC
516
VLPEQ
521
LSTMQ
526
LEGFQ
531
DLKNL
536
RTLYL
541
KSSLS
546
RIPQV
551
VTDLL
556
PSLQK
561
LSLDN
566
EGSKL
571
VVLNN
576
LKKMV
581
NLKSL
586
ELISC
591
DLERI
596
PHSIF
601
SLNNL
606
HELDL
611
RENNL
616
KTVEE
621
IISFQ
626
HLQNL
631
SCLKL
636
WHNNI
641
AYIPA
646
QIGAL
651
SNLEQ
656
LSLDH
661
NNIEN
666
LPLQL
671
FLCTK
676
LHYLD
681
LSYNH
686
LTFIP
691
EEIQY
696
LSNLQ
701
YFAVT
706
NNNIE
711
MLPDG
716
LFQCK
721
KLQCL
726
LLGKN
731
SLMNL
736
SPHVG
741
ELSNL
746
THLEL
751
IGNYL
756
ETLPP
761
ELEGC
766
QSLKR
771
NCLIV
776
EENLL
781
NTLPL
786
PVTER
791
LQTCL
796
DKC
801
Mutation Information
DNA mutation:
None
Peptide Range:
227 ~ 251
Mut AA position:
239 (13 in Wild Type peptide)
Alignment
Wild Type:
"DKKEGEQAKAIFEKVKRFRMHVEQK
||||||||||||.||||||||||||
Mutant:
DKKEGEQAKAIFGKVKRFRMHVEQK"
Clin Cancer Res, 2017
Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 ExpressionGene Name (from Reference) LRRC8B
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
ELISPOT assay