Immunogenicity 10912

summary
Sample ID
3678
Response
Negative
Tumor Type
Melanoma
Gene Symbol
LRRK1
Transcript ID
None
HLA INFO
A*03:01
TCR INFO

No TCR info found!

T cell Tumor cell A*03:01
sequence
Full length protein sequence (2015 aa)
MAGMS
1
QRPPS
6
MYWCV
11
GPEES
16
AVCPE
21
RAMET
26
LNGAG
31
DTGGK
36
PSTRG
41
GDPAA
46
RSRRT
51
EGIRA
56
AYRRG
61
DRGGA
66
RDLLE
71
EACDQ
76
CASQL
81
EKGQL
86
LSIPA
91
AYGDL
96
EMVRY
101
LLSKR
106
LVELP
111
TEPTD
116
DNPAV
121
VAAYF
126
GHTAV
131
VQELL
136
ESLPG
141
PCSPQ
146
RLLNW
151
MLALA
156
CQRGH
161
LGVVK
166
LLVLT
171
HGADP
176
ESYAV
181
RKNEF
186
PVIVR
191
LPLYA
196
AIKSG
201
NEDIA
206
IFLLR
211
HGAYF
216
CSYIL
221
LDSPD
226
PSKHL
231
LRKYF
236
IEASP
241
LPSSY
246
PGKTA
251
LRVKW
256
SHLRL
261
PWVDL
266
DWLID
271
ISCQI
276
TELDL
281
SANCL
286
ATLPS
291
VIPWG
296
LINLR
301
KLNLS
306
DNHLG
311
ELPGV
316
QSSDE
321
IICSR
326
LLEID
331
ISSNK
336
LSHLP
341
PGFLH
346
LSKLQ
351
KLTAS
356
KNCLE
361
KLFEE
366
ENATN
371
WIGLR
376
KLQEL
381
DISDN
386
KLTEL
391
PALFL
396
HSFKS
401
LNSLN
406
VSRNN
411
LKVFP
416
DPWAC
421
PLKCC
426
KASRN
431
ALECL
436
PDKMA
441
VFWKN
446
HLKDV
451
DFSEN
456
ALKEV
461
PLGLF
466
QLDAL
471
MFLRL
476
QGNQL
481
AALPP
486
QEKWT
491
CRQLK
496
TLDLS
501
RNQLG
506
KNEDG
511
LKTKR
516
IAFFT
521
TRGRQ
526
RSGTE
531
AASVL
536
EFPAF
541
LSESL
546
EVLCL
551
NDNHL
556
DTVPP
561
SVCLL
566
KSLSE
571
LYLGN
576
NPGLR
581
ELPPE
586
LGQLG
591
NLWQL
596
DTEDL
601
TISNV
606
PAEIQ
611
KEGPK
616
AMLSY
621
LRAQL
626
RKAEK
631
CKLMK
636
MIIVG
641
PPRQG
646
KSTLL
651
EILQT
656
GRAPQ
661
VVHGE
666
ATIRT
671
TKWEL
676
QRPAG
681
SRAKV
686
ESVEF
691
NVWDI
696
GGPAS
701
MATVN
706
QCFFT
711
DKALY
716
VVVWN
721
LALGE
726
EAVAN
731
LQFWL
736
LNIEA
741
KAPNA
746
VVLVV
751
GTHLD
756
LIEAK
761
FRVER
766
IATLR
771
AYVLA
776
LCRSP
781
SGSRA
786
TGFPD
791
ITFKH
796
LHEIS
801
CKSLE
806
GQEGL
811
RQLIF
816
HVTCS
821
MKDVG
826
STIGC
831
QRLAG
836
RLIPR
841
SYLSL
846
QEAVL
851
AEQQR
856
RSRDD
861
DVQYL
866
TDRQL
871
EQLVE
876
QTPDN
881
DIKDY
886
EDLQS
891
AISFL
896
IETGT
901
LLHFP
906
DTSHG
911
LRNLY
916
FLDPI
921
WLSEC
926
LQRIF
931
NIKGS
936
RSVAK
941
NGVIR
946
AEDLR
951
MLLVG
956
TGFTQ
961
QTEEQ
966
YFQFL
971
AKFEI
976
ALPVA
981
NDSYL
986
LPHLL
991
PSKPG
996
LDTHG
1001
MRHPT
1006
ANTIQ
1011
RVFKM
1016
SFVPV
1021
GFWQR
1026
FIARM
1031
LISLA
1036
EMDLQ
1041
LFENK
1046
KNTKS
1051
RNRKV
1056
TIYSF
1061
TGNQR
1066
NRCST
1071
FRVKR
1076
NQTIY
1081
WQEGL
1086
LVTFD
1091
GGYLS
1096
VESSD
1101
VNWKK
1106
KKSGG
1111
MKIVC
1116
QSEVR
1121
DFSAM
1126
AFITD
1131
HVNSL
1136
IDQWF
1141
PALTA
1146
TESDG
1151
TPLME
1156
QYVPC
1161
PVCET
1166
AWAQH
1171
TDPSE
1176
KSEDV
1181
QYFDM
1186
EDCVL
1191
TAIER
1196
DFISC
1201
PRHPD
1206
LPVPL
1211
QELVP
1216
ELFMT
1221
DFPAR
1226
LFLEN
1231
SKLEH
1236
SEDEG
1241
SVLGQ
1246
GGSGT
1251
VIYRA
1256
RYQGQ
1261
PVAVK
1266
RFHIK
1271
KFKNF
1276
ANVPA
1281
DTMLR
1286
HLRAT
1291
DAMKN
1296
FSEFR
1301
QEASM
1306
LHALQ
1311
HPCIV
1316
ALIGI
1321
SIHPL
1326
CFALE
1331
LAPLS
1336
SLNTV
1341
LSENA
1346
RDSSF
1351
IPLGH
1356
MLTQK
1361
IAYQI
1366
ASGLA
1371
YLHKK
1376
NIIFC
1381
DLKSD
1386
NILVW
1391
SLDVK
1396
EHINI
1401
KLSDY
1406
GISRQ
1411
SFHEG
1416
ALGVE
1421
GTPGY
1426
QAPEI
1431
RPRIV
1436
YDEKV
1441
DMFSY
1446
GMVLY
1451
ELLSG
1456
QRPAL
1461
GHHQL
1466
QIAKK
1471
LSKGI
1476
RPVLG
1481
QPEEV
1486
QFRRL
1491
QALMM
1496
ECWDT
1501
KPEKR
1506
PLALS
1511
VVSQM
1516
KDPTF
1521
ATFMY
1526
ELCCG
1531
KQTAF
1536
FSSQG
1541
QEYTV
1546
VFWDG
1551
KEESR
1556
NYTVV
1561
NTEKG
1566
LMEVQ
1571
RMCCP
1576
GMKVS
1581
CQLQV
1586
QRSLW
1591
TATED
1596
QKIYI
1601
YTLKG
1606
MCPLN
1611
TPQQA
1616
LDTPA
1621
VVTCF
1626
LAVPV
1631
IKKNS
1636
YLVLA
1641
GLADG
1646
LVAVF
1651
PVVRG
1656
TPKDS
1661
CSYLC
1666
SHTAN
1671
RSKFS
1676
IADED
1681
ARQNP
1686
YPVKA
1691
MEVVN
1696
SGSEV
1701
WYSNG
1706
PGLLV
1711
IDCAS
1716
LEICR
1721
RLEPY
1726
MAPSM
1731
VTSVV
1736
CSSEG
1741
RGEEV
1746
VWCLD
1751
DKANS
1756
LVMYH
1761
STTYQ
1766
LCARY
1771
FCGVP
1776
SPLRD
1781
MFPVR
1786
PLDTE
1791
PPAAS
1796
HTANP
1801
KVPEG
1806
DSIAD
1811
VSIMY
1816
SEELG
1821
TQILI
1826
HQESL
1831
TDYCS
1836
MSSYS
1841
SSPPR
1846
QAARS
1851
PSSLP
1856
SSPAS
1861
SSSVP
1866
FSTDC
1871
EDSDM
1876
LHTPG
1881
AASDR
1886
SEHDL
1891
TPMDG
1896
ETFSQ
1901
HLQAV
1906
KILAV
1911
RDLIW
1916
VPRRG
1921
GDVIV
1926
IGLEK
1931
DSGAQ
1936
RGRVI
1941
AVLKA
1946
RELTP
1951
HGVLV
1956
DAAVV
1961
AKDTV
1966
VCTFE
1971
NENTE
1976
WCLAV
1981
WRGWG
1986
AREFD
1991
IFYQS
1996
YEELG
2001
RLEAC
2006
TRKRR
2011
Mutation Information
DNA mutation:
None
Peptide Range:
101 ~ 125
Mut AA position:
113 (13 in Wild Type peptide)
Alignment
Wild Type:
"EMVRYLLSKRLVELPTEPTDDNPAV
||||||||||||.||||||||||||
Mutant:
EMVRYLLSKRLVKLPTEPTDDNPAV"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

ELISPOT assay