Immunogenicity 10928
Sample ID
3678
Response
Negative
Tumor Type
Melanoma
Gene Symbol
MSH3
Transcript ID
None
HLA INFO
A*03:01
TCR INFO
No TCR info found!
Full length protein sequence (1137 aa)
MSRRK
1
PASGG
6
LAASS
11
SAPAR
16
QAVLS
21
RFFQS
26
TGSLK
31
STSSS
36
TGAAD
41
QVDPG
46
AAAAA
51
AAAAA
56
AAPPA
61
PPAPA
66
FPPQL
71
PPHIA
76
TEIDR
81
RKKRP
86
LENDG
91
PVKKK
96
VKKVQ
101
QKEGG
106
SDLGM
111
SGNSE
116
PKKCL
121
RTRNV
126
SKSLE
131
KLKEF
136
CCDSA
141
LPQSR
146
VQTES
151
LQERF
156
AVLPK
161
CTDFD
166
DISLL
171
HAKNA
176
VSSED
181
SKRQI
186
NQKDT
191
TLFDL
196
SQFGS
201
SNTSH
206
ENLQK
211
TASKS
216
ANKRS
221
KSIYT
226
PLELQ
231
YIEMK
236
QQHKD
241
AVLCV
246
ECGYK
251
YRFFG
256
EDAEI
261
AAREL
266
NIYCH
271
LDHNF
276
MTASI
281
PTHRL
286
FVHVR
291
RLVAK
296
GYKVG
301
VVKQT
306
ETAAL
311
KAIGD
316
NRSSL
321
FSRKL
326
TALYT
331
KSTLI
336
GEDVN
341
PLIKL
346
DDAVN
351
VDEIM
356
TDTST
361
SYLLC
366
ISENK
371
ENVRD
376
KKKGN
381
IFIGI
386
VGVQP
391
ATGEV
396
VFDSF
401
QDSAS
406
RSELE
411
TRMSS
416
LQPVE
421
LLLPS
426
ALSEQ
431
TEALI
436
HRATS
441
VSVQD
446
DRIRV
451
ERMDN
456
IYFEY
461
SHAFQ
466
AVTEF
471
YAKDT
476
VDIKG
481
SQIIS
486
GIVNL
491
EKPVI
496
CSLAA
501
IIKYL
506
KEFNL
511
EKMLS
516
KPENF
521
KQLSS
526
KMEFM
531
TINGT
536
TLRNL
541
EILQN
546
QTDMK
551
TKGSL
556
LWVLD
561
HTKTS
566
FGRRK
571
LKKWV
576
TQPLL
581
KLREI
586
NARLD
591
AVSEV
596
LHSES
601
SVFGQ
606
IENHL
611
RKLPD
616
IERGL
621
CSIYH
626
KKCST
631
QEFFL
636
IVKTL
641
YHLKS
646
EFQAI
651
IPAVN
656
SHIQS
661
DLLRT
666
VILEI
671
PELLS
676
PVEHY
681
LKILN
686
EQAAK
691
VGDKT
696
ELFKD
701
LSDFP
706
LIKKR
711
KDEIQ
716
GVIDE
721
IRMHL
726
QEIRK
731
ILKNP
736
SAQYV
741
TVSGQ
746
EFMIE
751
IKNSA
756
VSCIP
761
TDWVK
766
VGSTK
771
AVSRF
776
HSPFI
781
VENYR
786
HLNQL
791
REQLV
796
LDCSA
801
EWLDF
806
LEKFS
811
EHYHS
816
LCKAV
821
HHLAT
826
VDCIF
831
SLAKV
836
AKQGD
841
YCRPT
846
VQEER
851
KIVIK
856
NGRHP
861
VIDVL
866
LGEQD
871
QYVPN
876
NTDLS
881
EDSER
886
VMIIT
891
GPNMG
896
GKSSY
901
IKQVA
906
LITIM
911
AQIGS
916
YVPAE
921
EATIG
926
IVDGI
931
FTRMG
936
AADNI
941
YKGQS
946
TFMEE
951
LTDTA
956
EIIRK
961
ATSQS
966
LVILD
971
ELGRG
976
TSTHD
981
GIAIA
986
YATLE
991
YFIRD
996
VKSLT
1001
LFVTH
1006
YPPVC
1011
ELEKN
1016
YSHQV
1021
GNYHM
1026
GFLVS
1031
EDESK
1036
LDPGA
1041
AEQVP
1046
DFVTF
1051
LYQIT
1056
RGIAA
1061
RSYGL
1066
NVAKL
1071
ADVPG
1076
EILKK
1081
AAHKS
1086
KELEG
1091
LINTK
1096
RKRLK
1101
YFAKL
1106
WTMHN
1111
AQDLQ
1116
KWTEE
1121
FNMEE
1126
TQTSL
1131
LH
1136
Mutation Information
DNA mutation:
None
Peptide Range:
771 ~ 795
Mut AA position:
783 (13 in Wild Type peptide)
Alignment
Wild Type:
"VGSTKAVSRFHSPFIVENYRHLNQL
||||||||||||.||||||||||||
Mutant:
VGSTKAVSRFHSSFIVENYRHLNQL"
Clin Cancer Res, 2017
Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 ExpressionGene Name (from Reference) MSH3
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
ELISPOT assay