Immunogenicity 10952
Sample ID
3678
Response
Negative
Tumor Type
Melanoma
Gene Symbol
NOTCH2
Transcript ID
None
HLA INFO
A*03:01
TCR INFO
No TCR info found!
Full length protein sequence (1235 aa)
MPALR
1
PALLW
6
ALLAL
11
WLCCA
16
APAHA
21
LQCRD
26
GYEPC
31
VNEGM
36
CVTYH
41
NGTGY
46
CKCPE
51
GFLGE
56
YCQHR
61
DPCEK
66
NRCQN
71
GGTCV
76
AQAML
81
GKATC
86
RCASG
91
FTGED
96
CQYST
101
SHPCF
106
VSRPC
111
LNGGT
116
CHMLS
121
RDTYE
126
CTCQV
131
GFTGK
136
ECQWT
141
DACLS
146
HPCAN
151
GSTCT
156
TVANQ
161
FSCKC
166
LTGFT
171
GQKCE
176
TDVNE
181
CDIPG
186
HCQHG
191
GTCLN
196
LPGSY
201
QCQCP
206
QGFTG
211
QYCDS
216
LYVPC
221
APSPC
226
VNGGT
231
CRQTG
236
DFTFE
241
CNCLP
246
GFEGS
251
TCERN
256
IDDCP
261
NHRCQ
266
NGGVC
271
VDGVN
276
TYNCR
281
CPPQW
286
TGQFC
291
TEDVD
296
ECLLQ
301
PNACQ
306
NGGTC
311
ANRNG
316
GYGCV
321
CVNGW
326
SGDDC
331
SENID
336
DCAFA
341
SCTPG
346
STCID
351
RVASF
356
SCMCP
361
EGKAG
366
LLCHL
371
DDACI
376
SNPCH
381
KGALC
386
DTNPL
391
NGQYI
396
CTCPQ
401
GYKGA
406
DCTED
411
VDECA
416
MANSN
421
PCEHA
426
GKCVN
431
TDGAF
436
HCECL
441
KGYAG
446
PRCEM
451
DINEC
456
HSDPC
461
QNDAT
466
CLDKI
471
GGFTC
476
LCMPG
481
FKGVH
486
CELEI
491
NECQS
496
NPCVN
501
NGQCV
506
DKVNR
511
FQCLC
516
PPGFT
521
GPVCQ
526
IDIDD
531
CSSTP
536
CLNGA
541
KCIDH
546
PNGYE
551
CQCAT
556
GFTGV
561
LCEEN
566
IDNCD
571
PDPCH
576
HGQCQ
581
DGIDS
586
YTCIC
591
NPGYM
596
GAICS
601
DQIDE
606
CYSSP
611
CLNDG
616
RCIDL
621
VNGYQ
626
CNCQP
631
GTSGV
636
NCEIN
641
FDDCA
646
SNPCI
651
HGICM
656
DGINR
661
YSCVC
666
SPGFT
671
GQRCN
676
IDIDE
681
CASNP
686
CRKGA
691
TCING
696
VNGFR
701
CICPE
706
GPHHP
711
SCYSQ
716
VNECL
721
SNPCI
726
HGNCT
731
GGLSG
736
YKCLC
741
DAGWV
746
GINCE
751
VDKNE
756
CLSNP
761
CQNGG
766
TCDNL
771
VNGYR
776
CTCKK
781
GFKGY
786
NCQVN
791
IDECA
796
SNPCL
801
NQGTC
806
FDDIS
811
GYTCH
816
CVLPY
821
TGKNC
826
QTVLA
831
PCSPN
836
PCENA
841
AVCKE
846
SPNFE
851
SYTCL
856
CAPGW
861
QGQRC
866
TIDID
871
ECISK
876
PCMNH
881
GLCHN
886
TQGSY
891
MCECP
896
PGFSG
901
MDCEE
906
DIDDC
911
LANPC
916
QNGGS
921
CMDGV
926
NTFSC
931
LCLPG
936
FTGDK
941
CQTDM
946
NECLS
951
EPCKN
956
GGTCS
961
DYVNS
966
YTCKC
971
QAGFD
976
GVHCE
981
NNINE
986
CTESS
991
CFNGG
996
TCVDG
1001
INSFS
1006
CLCPV
1011
GFTGS
1016
FCLHE
1021
INECS
1026
SHPCL
1031
NEGTC
1036
VDGLG
1041
TYRCS
1046
CPLGY
1051
TGKNC
1056
QTLVN
1061
LCSRS
1066
PCKNK
1071
GTCVQ
1076
KKAES
1081
QCLCP
1086
SGWAG
1091
AYCDV
1096
PNVSC
1101
DIAAS
1106
RRGVL
1111
VEHLC
1116
QHSGV
1121
CINAG
1126
NTHYC
1131
QCPLG
1136
YTGSY
1141
CEEQL
1146
DECAS
1151
NPCQH
1156
GATCS
1161
DFIGG
1166
YRCEC
1171
VPGYQ
1176
GVNCE
1181
YEVDE
1186
CQNQP
1191
CQNGG
1196
TCIDL
1201
VNHFK
1206
CSCPP
1211
GTRGM
1216
KSSLS
1221
IFHPG
1226
HCLKL
1231
Mutation Information
DNA mutation:
None
Peptide Range:
9 ~ 33
Mut AA position:
21 (13 in Wild Type peptide)
Alignment
Wild Type:
"LWALLALWLCCAAPAHALQCRDGYE
||||||||||||.||||||||||||
Mutant:
LWALLALWLCCATPAHALQCRDGYE"
Clin Cancer Res, 2017
Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 ExpressionGene Name (from Reference) NOTCH2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
ELISPOT assay