Immunogenicity 10970
Sample ID
3678
Response
Negative
Tumor Type
Melanoma
Gene Symbol
PACS1
Transcript ID
None
HLA INFO
B*44:02
TCR INFO
No TCR info found!
Full length protein sequence (963 aa)
MAERG
1
GAGGG
6
PGGAG
11
GGSGQ
16
RGSGV
21
AQSPQ
26
QPPPQ
31
QQQQQ
36
PPQQP
41
TPPKL
46
AQATS
51
SSSST
56
SAAAA
61
SSSSS
66
STSTS
71
MAVAV
76
ASGSA
81
PPGGP
86
GPGRT
91
PAPVQ
96
MNLYA
101
TWEVD
106
RSSSS
111
CVPRL
116
FSLTL
121
KKLVM
126
LKEMD
131
KDLNS
136
VVIAV
141
KLQGS
146
KRILR
151
SNEIV
156
LPASG
161
LVETE
166
LQLTF
171
SLQYP
176
HFLKR
181
DANKL
186
QIMLQ
191
RRKRY
196
KNRTI
201
LGYKT
206
LAVGL
211
INMAE
216
VMQHP
221
NEGAL
226
VLGLH
231
SNVKD
236
VSVPV
241
AEIKI
246
YSLSS
251
QPIDH
256
EGIKS
261
KLSDR
266
SPDID
271
NYSEE
276
EEESF
281
SSEQE
286
GSDDP
291
LHGQD
296
LFYED
301
EDLRK
306
VKKTR
311
RKLTS
316
TSAIT
321
RQPNI
326
KQKFV
331
ALLKR
336
FKVSD
341
EVGFG
346
LEHVS
351
REQIR
356
EVEED
361
LDELY
366
DSLEM
371
YNPSD
376
SGPEM
381
EETES
386
ILSTP
391
KPKLK
396
PFFEG
401
MSQSS
406
SQTEI
411
GSLNS
416
KGSLG
421
KDTTS
426
PMELA
431
ALEKI
436
KSTWI
441
KNQDD
446
SLTET
451
DTLEI
456
TDQDM
461
FGDAS
466
TSLVV
471
PEKVK
476
TPMKS
481
SKTDL
486
QGSAS
491
PSKVE
496
GVHTP
501
RQKRS
506
TPLKE
511
RQLSK
516
PLSER
521
TNSSD
526
SERSP
531
DLGHS
536
TQIPR
541
KVVYD
546
QLNQI
551
LVSDA
556
ALPEN
561
VILVN
566
TTDWQ
571
GQYVA
576
ELLQD
581
QRKPV
586
VCTCS
591
TVEVQ
596
AVLSA
601
LLTRI
606
QRYCN
611
CNSSM
616
PRPVK
621
VAAVG
626
GQSYL
631
SSILR
636
FFVKS
641
LANKT
646
SDWLG
651
YMRFL
656
IIPLG
661
SHPVA
666
KYLGS
671
VDSKY
676
SSSFL
681
DSGWR
686
DLFSR
691
SEPPV
696
SEQLD
701
VAGRV
706
MQYVN
711
GAATT
716
HQLPV
721
AEAML
726
TCRHK
731
FPDED
736
SYQKF
741
IPFIG
746
VVKVG
751
LVEDS
756
PSTAG
761
DGDDS
766
PVVSL
771
TVPST
776
SPPSS
781
SGLSR
786
DATAT
791
PPSSP
796
SMSSA
801
LAIVG
806
SPNSP
811
YGDVI
816
GLQVD
821
YWLGH
826
PGERR
831
REGDK
836
RDASS
841
KNTLK
846
SVFRS
851
VQVSR
856
LPHSG
861
EAQLS
866
GTMAM
871
TVVTK
876
EKNKK
881
VPTIF
886
LSKKP
891
REKEV
896
DSKSQ
901
VIEGI
906
SRLIC
911
SAKQQ
916
QTMLR
921
VSIDG
926
VEWSD
931
IKFFQ
936
LAAQW
941
PTHVK
946
HFPVG
951
LFSGS
956
KAT
961
Mutation Information
DNA mutation:
None
Peptide Range:
107 ~ 131
Mut AA position:
119 (13 in Wild Type peptide)
Alignment
Wild Type:
"WEVDRSSSSCVPRLFSLTLKKLVML
||||||||||||.||||||||||||
Mutant:
WEVDRSSSSCVPKLFSLTLKKLVML"
Clin Cancer Res, 2017
Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 ExpressionGene Name (from Reference) PACS1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
ELISPOT assay