Immunogenicity 10981

summary
Sample ID
3678
Response
Negative
Tumor Type
Melanoma
Gene Symbol
PCLO
Transcript ID
None
HLA INFO
C*14:02
TCR INFO

No TCR info found!

T cell Tumor cell C*14:02
sequence
Full length protein sequence (2838 aa)
MGNEA
1
SLEGE
6
GLPEG
11
LAAAA
16
AAGGG
21
ASGAG
26
SPSHT
31
AIPAG
36
MEADL
41
SQLSE
46
EERRQ
51
IAAVM
56
SRAQG
61
LPKGS
66
VPPAA
71
AESPS
76
MHRKQ
81
ELDSS
86
HPPKQ
91
SGRPP
96
DPGRP
101
AQPGL
106
SKSRT
111
TDTFR
116
SEQKL
121
PGRSP
126
STISL
131
KESKS
136
RTDLK
141
EEHKS
146
SMMPG
151
FLSEV
156
NALSA
161
VSSVV
166
NKFNP
171
FDLIS
176
DSEAS
181
QEETT
186
KKQKV
191
VQKEQ
196
GKPEG
201
IIKPP
206
LQQQP
211
PKPIP
216
KQQGP
221
GRDPL
226
QQDGT
231
PKSIS
236
SQQPE
241
KIKSQ
246
PPGTG
251
KPIQG
256
PTQTP
261
QTDHA
266
KLPLQ
271
RDASR
276
PQTKQ
281
ADIVR
286
GESVK
291
PSLPS
296
PSKPP
301
IQQPT
306
PGKPP
311
AQQPG
316
HEKSQ
321
PGPAK
326
PPAQP
331
SGLTK
336
PLAQQ
341
PGTVK
346
PPVQP
351
PGTTK
356
PPAQP
361
LGPAK
366
PPAQQ
371
TGSEK
376
PSSEQ
381
PGPKA
386
LAQPP
391
GVGKT
396
PAQQP
401
GPAKP
406
PTQQV
411
GTPKP
416
LAQQP
421
GLQSP
426
AKAPG
431
PTKTP
436
VQQPG
441
PGKIP
446
AQQAG
451
PGKTS
456
AQQTG
461
PTKPP
466
SQLPG
471
PAKPP
476
PQQPG
481
PAKPP
486
PQQPG
491
SAKPP
496
SQQPG
501
STKPP
506
PQQPG
511
PAKPS
516
PQQPG
521
STKPP
526
SQQPG
531
SAKPS
536
AQQPS
541
PAKPS
546
AQQST
551
KPVSQ
556
TGSGK
561
PLQPP
566
TVSPS
571
AKQPP
576
SQGLP
581
KTICP
586
LCNTT
591
ELLLH
596
VPEKA
601
NFNTC
606
TECQT
611
TVCSL
616
CGFNP
621
NPHLT
626
EVKEW
631
LCLNC
636
QMKRA
641
LGGDL
646
APVPS
651
SPQPK
656
LKTAP
661
VTTTS
666
AVSKS
671
SPQPQ
676
QTSPK
681
KDAAP
686
KQDLS
691
KAPEP
696
KKPPP
701
LVKQP
706
TLHGS
711
PSAKA
716
KQPPE
721
ADSLS
726
KPAPP
731
KEPSV
736
PSEQD
741
KAPVA
746
DDKPK
751
QPKMV
756
KPTTD
761
LVSSS
766
SATTK
771
PDIPS
776
SKVQS
781
QAEEK
786
TTPPL
791
KTDSA
796
KPSQS
801
FPPTG
806
EKVSP
811
FDSKA
816
IPRPA
821
SDSKI
826
ISHPG
831
PSSES
836
KGQKQ
841
VDPVQ
846
KKEEP
851
KKAQT
856
KMSPK
861
PDAKP
866
MPKGS
871
PTPPG
876
PRPTA
881
GQTVP
886
TPQQS
891
PKPQE
896
QSRRF
901
SLNLG
906
SITDA
911
PKSQP
916
TTPQE
921
TVTGK
926
LFGFG
931
ASIFS
936
QASNL
941
ISTAG
946
QPGPH
951
SQSGP
956
GAPMK
961
QAPAP
966
SQPPT
971
SQGPP
976
KSTGQ
981
APPAP
986
AKSIP
991
VKKET
996
KAPAA
1001
EKLEP
1006
KAEQA
1011
PTVKR
1016
TETEK
1021
KPPPI
1026
KDSKS
1031
LTAEP
1036
QKAVL
1041
PTKLE
1046
KSPKP
1051
ESTCP
1056
LCKTE
1061
LNIGS
1066
KDPPN
1071
FNTCT
1076
ECKNQ
1081
VCNLC
1086
GFNPT
1091
PHLTE
1096
IQEWL
1101
CLNCQ
1106
TQRAI
1111
SGQLG
1116
DIRKM
1121
PPAPS
1126
GPKAS
1131
PMPVP
1136
TESSS
1141
QKTAV
1146
PPQVK
1151
LVKKQ
1156
EQEVK
1161
TEAEK
1166
VILEK
1171
VKETL
1176
SMEKI
1181
PPMVT
1186
TDQKQ
1191
EESKL
1196
EKDKA
1201
SALQE
1206
KKPLP
1211
EEKKL
1216
IPEEE
1221
KIRSE
1226
EKKPL
1231
LEEKK
1236
PTPED
1241
KKLLP
1246
EAKTS
1251
APEEQ
1256
KHDLL
1261
KSQVQ
1266
IAEEK
1271
LEGRV
1276
APKTV
1281
QEGKQ
1286
PQTKM
1291
EGLPS
1296
GTPQS
1301
LPKED
1306
DKTTK
1311
TIKEQ
1316
PQPPC
1321
TAKPD
1326
QVEPG
1331
KEKTT
1336
KGSQT
1341
MTSSG
1346
AQKKV
1351
KRTLP
1356
NPPPE
1361
EISTG
1366
TQSTF
1371
STMGT
1376
VSRRR
1381
ICRTN
1386
TMARA
1391
KILQD
1396
IDREL
1401
DLVER
1406
ESAKL
1411
RKKQA
1416
ELDEE
1421
EKEID
1426
AKLRY
1431
LEMGI
1436
NRRKE
1441
ALLKE
1446
REKRE
1451
RAYLQ
1456
GVAED
1461
RDYMS
1466
DSEVS
1471
STRPT
1476
RIESQ
1481
HGIER
1486
PRTAP
1491
QTEFS
1496
QFIPP
1501
QTQTE
1506
SQLVP
1511
PTSPY
1516
TQYQY
1521
SSPAL
1526
PTQAP
1531
TSYTQ
1536
QSHFE
1541
QQTLY
1546
HQQVS
1551
PYQTQ
1556
PTFQA
1561
VATMS
1566
FTPQV
1571
QPTPT
1576
PQPSY
1581
QLPSQ
1586
MMVIQ
1591
QKPRQ
1596
TTLYL
1601
EPKIT
1606
SNYEV
1611
IRNQP
1616
LMIAP
1621
VSTDN
1626
TFAVS
1631
HLGSK
1636
YNSLD
1641
LRIGL
1646
EERSS
1651
MASSP
1656
ISSIS
1661
ADSFY
1666
ADIDH
1671
HTPRN
1676
YVLID
1681
DIGEI
1686
TKGTA
1691
ALSTA
1696
FSLHE
1701
KDLSK
1706
TDRLL
1711
RTTET
1716
RRSQE
1721
VTDFL
1726
APLQS
1731
SSRLH
1736
SYVKA
1741
EEDPM
1746
EDPYE
1751
LKLLK
1756
HQIKQ
1761
EFRRG
1766
TESLD
1771
HLAGL
1776
SHYYH
1781
ADTSY
1786
RHFPK
1791
SEKYS
1796
ISRLT
1801
LEKQA
1806
AKQLP
1811
AAILY
1816
QKQSK
1821
HKKSL
1826
IDPKM
1831
SKFSP
1836
IQESR
1841
DLEPD
1846
YSSYM
1851
TSSTS
1856
SIGGI
1861
SSRAR
1866
LLQDD
1871
ITFGL
1876
RKNIT
1881
DQQKF
1886
MGSSL
1891
GTGLG
1896
TLGNT
1901
IRSAL
1906
QDEAD
1911
KPYSS
1916
GSRSR
1921
PSSRP
1926
SSVYG
1931
LDLSI
1936
KRDSS
1941
SSSLR
1946
LKAQE
1951
AEALD
1956
VSFSH
1961
ASSSA
1966
RTKPT
1971
SLPIS
1976
QSRGR
1981
IPIVA
1986
QNSEE
1991
ESPLS
1996
PVGQP
2001
MGMAR
2006
AAAGP
2011
LPPIS
2016
ADTRD
2021
QFGSS
2026
HSLPE
2031
VQQHM
2036
REESR
2041
TRGYD
2046
RDIAF
2051
IMDDF
2056
QHAMS
2061
DSEAY
2066
HLRRE
2071
ETDWF
2076
DKPRE
2081
SRLEN
2086
GHGLD
2091
RKLPE
2096
RLVHS
2101
RPLSQ
2106
HQEQI
2111
IQMNG
2116
KTMHY
2121
IFPHA
2126
RIKIT
2131
RDSKD
2136
HTVSG
2141
NGLGI
2146
RIVGG
2151
KEIPG
2156
HSGEI
2161
GAYIA
2166
KILPG
2171
GSAEQ
2176
TGKLM
2181
EGMQV
2186
LEWNG
2191
IPLTS
2196
KTYEE
2201
VQSII
2206
SQQSG
2211
EAEIC
2216
VRLDL
2221
NMLSD
2226
SENSQ
2231
HLELH
2236
EPPKA
2241
VDKAK
2246
SPGVD
2251
PKQLA
2256
AELQK
2261
VSLQQ
2266
SPLVL
2271
SSVVE
2276
KGSHV
2281
HSGPT
2286
SAGSS
2291
SVPSP
2296
GQPGS
2301
PSVSK
2306
KKHGS
2311
SKPTD
2316
GTKVV
2321
SHPIT
2326
GEIQL
2331
QINYD
2336
LGNLI
2341
IHILQ
2346
ARNLV
2351
PRDNN
2356
GYSDP
2361
FVKVY
2366
LLPGR
2371
GQVMV
2376
VQNAS
2381
AEYKR
2386
RTKHV
2391
QKSLN
2396
PEWNQ
2401
TVIYK
2406
SISME
2411
QLKKK
2416
TLEVT
2421
VWDYD
2426
RFSSN
2431
DFLGE
2436
VLIDL
2441
SSTSH
2446
LDNTP
2451
RWYPL
2456
KEQTE
2461
SIDHG
2466
KSHSS
2471
QSSQQ
2476
SPKPS
2481
VIKSR
2486
SHGIF
2491
PDPSK
2496
DMQVP
2501
TIEKS
2506
HSSPG
2511
SSKSS
2516
SEGHL
2521
RSHGP
2526
SRSQS
2531
KTSVT
2536
QTHLE
2541
DAGAA
2546
IAAAE
2551
AAVQQ
2556
LRIQP
2561
TAHKS
2566
GQSNH
2571
ARKQH
2576
RHSIA
2581
GVLPI
2586
QRTQS
2591
DNLPP
2596
PANGN
2601
QDQSQ
2606
LALRK
2611
VMSDG
2616
PVKPE
2621
GAKPP
2626
NHRPA
2631
ESSVS
2636
TGSSG
2641
SSFGS
2646
GYSVD
2651
SEGSS
2656
STAGE
2661
TNLFP
2666
IPRIG
2671
KMGQN
2676
GQEPV
2681
KQPGV
2686
GVGLA
2691
DTEAK
2696
TQVMG
2701
EIKIA
2706
LKKEM
2711
KTDGE
2716
QLIVE
2721
ILQCR
2726
NITYK
2731
FKSPD
2736
HLPDL
2741
YVKIY
2746
VMNIS
2751
TQKKV
2756
IKKKT
2761
RVCRH
2766
DREPS
2771
FNETF
2776
RFSLS
2781
PAGHS
2786
LQILL
2791
FSNGG
2796
KFMKK
2801
TLIGE
2806
ACIWL
2811
DKVDL
2816
RKRIV
2821
NWHKL
2826
LVSPT
2831
QTH
2836
Mutation Information
DNA mutation:
None
Peptide Range:
300 ~ 324
Mut AA position:
312 (13 in Wild Type peptide)
Alignment
Wild Type:
"SPSKPPIQQPTPGKPPAQQPGHEKS
||||||||||||.||||||||||||
Mutant:
SPSKPPIQQPTPVKPPAQQPGHEKS"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

ELISPOT assay