Immunogenicity 10999

summary
Sample ID
3678
Response
Negative
Tumor Type
Melanoma
Gene Symbol
PHRF1
Transcript ID
None
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (1645 aa)
MDDDS
1
LDELV
6
ARSPG
11
PDGHP
16
QVGPA
21
DPAES
26
SVGSS
31
GDSGD
36
DSDSE
41
HGDGT
46
DGEDE
51
GASEE
56
EDLED
61
RSGSE
66
DSEDD
71
GETLL
76
EVAGT
81
QGKLE
86
AAGSF
91
NSDDD
96
AESCP
101
ICLNA
106
FRDQA
111
VGTPE
116
NCAHY
121
FCLDC
126
IVEWS
131
KNANS
136
CPVDR
141
TLFKC
146
ICIRA
151
QFGGK
156
ILRKI
161
PVENT
166
KASEE
171
EEDPT
176
FCEVC
181
GRSDR
186
EDRLL
191
LCDGC
196
DAGYH
201
MECLD
206
PPLQE
211
VPVDE
216
WFCPE
221
CAAPG
226
VVLAA
231
DAGPV
236
SEEEV
241
SLLLA
246
DVVPT
251
TSRLR
256
PRAGR
261
TRAIA
266
RTRQS
271
ERVRA
276
TVNRN
281
RISTA
286
RRVQH
291
TPGRL
296
GSSLL
301
DEAIE
306
AVATG
311
LSTAV
316
YQRPL
321
TPRTP
326
ARRKR
331
KTRRR
336
KKVPG
341
RKKTP
346
SGPSA
351
KSKSS
356
ATRSK
361
KRQHR
366
VKKRR
371
GKKVK
376
SEATT
381
RSRIA
386
RTLGL
391
RRPVH
396
SSCIP
401
SVLKP
406
VEPSL
411
GLLRA
416
DIGAA
421
SLSLF
426
GDPYE
431
LDPFD
436
SSEEL
441
SANPL
446
SPLSA
451
KRRAL
456
SRSAL
461
QSHQP
466
VARPV
471
SVGLS
476
RRRLP
481
AAVPE
486
PDLEE
491
EPVPD
496
LLGSI
501
LSGQS
506
LLMLG
511
SSDVI
516
IHRDG
521
SLSAK
526
RAAPV
531
SFQRN
536
SGSLS
541
RGEEG
546
FKGCL
551
QPRAL
556
PSGSP
561
AQGPS
566
GNRPQ
571
STGLS
576
CQGRS
581
RTPAR
586
TAGAP
591
VRLDL
596
PAAPG
601
AVQAR
606
NLSNG
611
SVPGF
616
RQSHS
621
PWFNG
626
TNKHT
631
LPLAS
636
AASKI
641
SSRDS
646
KPPCR
651
SVVPG
656
PPLKP
661
APRRT
666
DISEL
671
PRIPK
676
IRRDD
681
GGGRR
686
DAAPA
691
HGQSI
696
EIPSA
701
CISRL
706
TGREG
711
TGQPG
716
RGTRA
721
ESEAS
726
SRVPR
731
EPGVH
736
TGSSR
741
PPAPS
746
SHGSL
751
APLGP
756
SRGKG
761
VGSTF
766
ESFRI
771
NIPGN
776
MAHSS
781
QLSSP
786
GFCNT
791
FRPVD
796
DKEQR
801
KENPS
806
PLFSI
811
KKTKQ
816
LRSEV
821
YDPSD
826
PTGSD
831
SSAPG
836
SSPER
841
SGPGL
846
LPSEI
851
TRTIS
856
INSPK
861
AQTVQ
866
AVRCV
871
TSYTV
876
ESIFG
881
TEPEP
886
PLGPS
891
SAMSK
896
LRGAV
901
AAEGA
906
SDTER
911
EEPTE
916
SQGLA
921
ARLRR
926
PSPPE
931
PWDEE
936
DGASC
941
STFFG
946
SEERT
951
VTCVT
956
VVEPE
961
APPSP
966
DVLQA
971
ATHRV
976
VELRP
981
PSRSR
986
STSSS
991
RSRKK
996
AKRKR
1001
VSREH
1006
GRTRS
1011
GTRSE
1016
SRDRS
1021
SRSAS
1026
PSVGE
1031
ERPRR
1036
QRSKA
1041
KSRRS
1046
SSDRS
1051
SSRER
1056
AKRKK
1061
AKDKS
1066
REHRR
1071
GPWGH
1076
SRRTS
1081
RSRSG
1086
SPGSS
1091
SYEHY
1096
ESRKK
1101
KKRRS
1106
ASRPR
1111
GRECS
1116
PTSSL
1121
ERLCR
1126
HKHQR
1131
ERSHE
1136
RPDRK
1141
ESVAW
1146
PRDRR
1151
KRRSR
1156
SPSSE
1161
HRARE
1166
HRRPR
1171
SREKW
1176
PQTRS
1181
HSPER
1186
KGAVR
1191
EASPA
1196
PLAQG
1201
EPGRE
1206
DLPTR
1211
LPALG
1216
EAHVS
1221
PEVAT
1226
ADKAP
1231
LQAPP
1236
VLEVA
1241
AECEP
1246
DDLDL
1251
DYGDS
1256
VEAGH
1261
VFDDF
1266
SSDAV
1271
FIQLD
1276
DMSSP
1281
PSPES
1286
TDSSP
1291
ERDFP
1296
LKPAL
1301
PPASL
1306
AVAAI
1311
QREVS
1316
LMHDE
1321
DPSQP
1326
PPLPE
1331
GTQEP
1336
HLLRP
1341
DAAEK
1346
AEAPS
1351
SPDVA
1356
PAGKE
1361
DSPSA
1366
SGRVQ
1371
EAARP
1376
EEVVS
1381
QTPLL
1386
RSRAL
1391
VKRVT
1396
WNLQE
1401
SESSA
1406
PAEDR
1411
APRAP
1416
LHRPQ
1421
KPREG
1426
AWDME
1431
DVAPT
1436
GVRQV
1441
FSELP
1446
FPSHV
1451
LPEPG
1456
FPDTD
1461
PSQVY
1466
SPGLP
1471
PAPAQ
1476
PSSIP
1481
PCALV
1486
SQPTV
1491
QFILQ
1496
GSLPL
1501
VGCGA
1506
AQTLA
1511
PVPAA
1516
LTPAS
1521
EPASQ
1526
ATAAS
1531
NSEEK
1536
TPAPR
1541
LAAEK
1546
TKKEE
1551
YMKKL
1556
HMQER
1561
AVEEV
1566
KLAIK
1571
PFYQK
1576
REVTK
1581
EEYKD
1586
ILRKA
1591
VQKIC
1596
HSKSG
1601
EINPV
1606
KVANL
1611
VKAYV
1616
DKYRH
1621
MRRHK
1626
KPEAG
1631
EEPPT
1636
QGAEG
1641
Mutation Information
DNA mutation:
None
Peptide Range:
312 ~ 336
Mut AA position:
324 (13 in Wild Type peptide)
Alignment
Wild Type:
"VATGLSTAVYQRPLTPRTPARRKRK
||||||||||||.||||||||||||
Mutant:
VATGLSTAVYQRLLTPRTPARRKRK"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

ELISPOT assay