Immunogenicity 11005
Sample ID
3678
Response
Negative
Tumor Type
Melanoma
Gene Symbol
PLXNB2
Transcript ID
None
HLA INFO
C*14:02
TCR INFO
No TCR info found!
Full length protein sequence (1838 aa)
MALQL
1
WALTL
6
LGLLG
11
AGASL
16
RPRKL
21
DFFRS
26
EKELN
31
HLAVD
36
EASGV
41
VYLGA
46
VNALY
51
QLDAK
56
LQLEQ
61
QVATG
66
PALDN
71
KKCTP
76
PIEAS
81
QCHEA
86
EMTDN
91
VNQLL
96
LLDPP
101
RKRLV
106
ECGSL
111
FKGIC
116
ALRAL
121
SNISL
126
RLFYE
131
DGSGE
136
KSFVA
141
SNDEG
146
VATVG
151
LVSST
156
GPGGD
161
RVLFV
166
GKGNG
171
PHDNG
176
IIVST
181
RLLDR
186
TDSRE
191
AFEAY
196
TDHAT
201
YKAGY
206
LSTNT
211
QQFVA
216
AFEDG
221
PYVFF
226
VFNQQ
231
DKHPA
236
RNRTL
241
LARMC
246
REDPN
251
YYSYL
256
EMDLQ
261
CRDPD
266
IHAAA
271
FGTCL
276
AASVA
281
APGSG
286
RVLYA
291
VFSRD
296
SRSSG
301
GPGAG
306
LCLFP
311
LDKVH
316
AKMEA
321
NRNAC
326
YTGTR
331
EARDI
336
FYKPF
341
HGDIQ
346
CGGHA
351
PGSSK
356
SFPCG
361
SEHLP
366
YPLGS
371
RDGLR
376
GTAVL
381
QRGGL
386
NLTAV
391
TVAAE
396
NNHTV
401
AFLGT
406
SDGRI
411
LKVYL
416
TPDGT
421
SSEYD
426
SILVE
431
INKRV
436
KRDLV
441
LSGDL
446
GSLYA
451
MTQDK
456
VFRLP
461
VQECL
466
SYPTC
471
TQCRD
476
SQDPY
481
CGWCV
486
VEGRC
491
TRKAE
496
CPRAE
501
EASHW
506
LWSRS
511
KSCVA
516
VTSAQ
521
PQNMS
526
RRAQG
531
EVQLT
536
VSPLP
541
ALSEE
546
DELLC
551
LFGES
556
PPHPA
561
RVEGE
566
AVICN
571
SPSSI
576
PVTPP
581
GQDHV
586
AVTIQ
591
LLLRR
596
GNIFL
601
TSYQY
606
PFYDC
611
RQAMS
616
LEENL
621
PCISC
626
VSNRW
631
TCQWD
636
LRYHE
641
CREAS
646
PNPED
651
GIVRA
656
HMEDS
661
CPQFL
666
GPSPL
671
VIPMN
676
HETDV
681
NFQGK
686
NLDTV
691
KGSSL
696
HVGSD
701
LLKFM
706
EPVTM
711
QESGT
716
FAFRT
721
PKLSH
726
DANET
731
LPLHL
736
YVKSY
741
GKNID
746
SKLHV
751
TLYNC
756
SFGRS
761
DCSLC
766
RAANP
771
DYRCA
776
WCGGQ
781
SRCVY
786
EALCN
791
TTSEC
796
PPPVI
801
TRIQP
806
ETGPL
811
GGGIR
816
ITILG
821
SNLGV
826
QAGDI
831
QRISV
836
AGRNC
841
SFQPE
846
RYSVS
851
TRIVC
856
VIEAA
861
ETPFT
866
GGVEV
871
DVFGK
876
LGRSP
881
PNVQF
886
TFQQP
891
KPLSV
896
EPQQG
901
PQAGG
906
TTLTI
911
HGTHL
916
DTGSQ
921
EDVRV
926
TLNGV
931
PCKVT
936
KFGAQ
941
LQCVT
946
GPQAT
951
RGQML
956
LEVSY
961
GGSPV
966
PNPGI
971
FFTYR
976
ENPVL
981
RAFEP
986
LRSFA
991
SGGRS
996
INVTG
1001
QGFSL
1006
IQRFA
1011
MVVIA
1016
EPLQS
1021
WQPPR
1026
EAESL
1031
QPMTV
1036
VGTDY
1041
VFHND
1046
TKVVF
1051
LSPAV
1056
PEEPE
1061
AYNLT
1066
VLIEM
1071
DGHRA
1076
LLRTE
1081
AGAFE
1086
YVPDP
1091
TFENF
1096
TGGVK
1101
KQVNK
1106
LIHAR
1111
GTNLN
1116
KAMTL
1121
QEAEA
1126
FVGAE
1131
RCTMK
1136
TLTET
1141
DLYCE
1146
PPEVQ
1151
PPPKR
1156
RQKRD
1161
TTHNL
1166
PEFIV
1171
KFGSR
1176
EWVLG
1181
RVEYD
1186
TRVSD
1191
VPLSL
1196
ILPLV
1201
IVPMV
1206
VVIAV
1211
SVYCY
1216
WRKSQ
1221
QAERE
1226
YEKIK
1231
SQLEG
1236
LEESV
1241
RDRCK
1246
KEFTD
1251
LMIEM
1256
EDQTN
1261
DVHEA
1266
GIPVL
1271
DYKTY
1276
TDRVF
1281
FLPSK
1286
DGDKD
1291
VMITG
1296
KLDIP
1301
EPRRP
1306
VVEQA
1311
LYQFS
1316
NLLNS
1321
KSFLI
1326
NFIHT
1331
LENQR
1336
EFSAR
1341
AKVYF
1346
ASLLT
1351
VALHG
1356
KLEYY
1361
TDIMH
1366
TLFLE
1371
LLEQY
1376
VVAKN
1381
PKLML
1386
RRSET
1391
VVERM
1396
LSNWM
1401
SICLY
1406
QYLKD
1411
SAGEP
1416
LYKLF
1421
KAIKH
1426
QVEKG
1431
PVDAV
1436
QKKAK
1441
YTLND
1446
TGLLG
1451
DDVEY
1456
APLTV
1461
SVIVQ
1466
DEGVD
1471
AIPVK
1476
VLNCD
1481
TISQV
1486
KEKII
1491
DQVYR
1496
GQPCS
1501
CWPRP
1506
DSVVL
1511
EWRPG
1516
STAQI
1521
LSDLD
1526
LTSQR
1531
EGRWK
1536
RVNTL
1541
MHYNV
1546
RDGAT
1551
LILSK
1556
VGVSQ
1561
QPEDS
1566
QQDLP
1571
GERHA
1576
LLEEE
1581
NRVWH
1586
LVRPT
1591
DEVDE
1596
GKSKR
1601
GSVKE
1606
KERTK
1611
AITEI
1616
YLTRL
1621
LSVKG
1626
TLQQF
1631
VDNFF
1636
QSVLA
1641
PGHAV
1646
PPAVK
1651
YFFDF
1656
LDEQA
1661
EKHNI
1666
QDEDT
1671
IHIWK
1676
TNSLP
1681
LRFWV
1686
NILKN
1691
PHFIF
1696
DVHVH
1701
EVVDA
1706
SLSVI
1711
AQTFM
1716
DACTR
1721
TEHKL
1726
SRDSP
1731
SNKLL
1736
YAKEI
1741
STYKK
1746
MVEDY
1751
YKGIR
1756
QMVQV
1761
SDQDM
1766
NTHLA
1771
EISRA
1776
HTDSL
1781
NTLVA
1786
LHQLY
1791
QYTQK
1796
YYDEI
1801
INALE
1806
EDPAA
1811
QKMQL
1816
AFRLQ
1821
QIAAA
1826
LENKV
1831
TDL
1836
Mutation Information
DNA mutation:
None
Peptide Range:
1515 ~ 1539
Mut AA position:
1527 (13 in Wild Type peptide)
Alignment
Wild Type:
"LEWRPGSTAQILSDLDLTSQREGRW
||||||||||||.||||||||||||
Mutant:
LEWRPGSTAQILLDLDLTSQREGRW"
Clin Cancer Res, 2017
Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 ExpressionGene Name (from Reference) PLXNB2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
ELISPOT assay