Immunogenicity 1104
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
MUC6
Transcript ID
ENST00000421673
HLA INFO
B*56:01
TCR INFO
No TCR info found!
Full length protein sequence (2439 aa)
MVQRW
1
LLLSC
6
CGALL
11
SAGLA
16
NTSYT
21
SPGLQ
26
RLKDS
31
PQTAP
36
DKGQC
41
STWGA
46
GHFST
51
FDHHV
56
YDFSG
61
TCNYI
66
FAATC
71
KDAFP
76
TFSVQ
81
LRRGP
86
DGSIS
91
RIIVE
96
LGASV
101
VTVSE
106
AIISV
111
KDIGV
116
ISLPY
121
TSNGL
126
QITPF
131
GQSVR
136
LVAKQ
141
LELEL
146
EVVWG
151
PDSHL
156
MVLVE
161
RKYMG
166
QMCGL
171
CGNFD
176
GKVTN
181
EFVSE
186
EGKFL
191
EPHKF
196
AALQK
201
LDDPG
206
EICTF
211
QDIPS
216
THVRQ
221
AQHAR
226
ICTQL
231
LTLVA
236
PECSV
241
SKEPF
246
VLSCQ
251
ADVAA
256
APQPG
261
PQNSS
266
CATLS
271
EYSRQ
276
CSMVG
281
QPVRR
286
WRSPG
291
LCSVG
296
QCPAN
301
QVYQE
306
CGSAC
311
VKTCS
316
NPQHS
321
CSSSC
326
TFGCF
331
CPEGT
336
VLNDL
341
SNNHT
346
CVPVT
351
QCPCV
356
LHGAM
361
YAPGE
366
VTIAA
371
CQTCR
376
CTLGR
381
WVCTE
386
RPCPG
391
HCSLE
396
GGSFV
401
TTFDA
406
RPYRF
411
HGTCT
416
YILLQ
421
SPQLP
426
EDGAL
431
MAVYD
436
KSGVS
441
HSETS
446
LVAVV
451
YLSRQ
456
DKIVI
461
SQDEV
466
VTNNG
471
EAKWL
476
PYKTR
481
NITVF
486
RQTST
491
HLQMA
496
TSFGL
501
ELVVQ
506
LRPIF
511
QAYVT
516
VGPQF
521
RGQTR
526
GLCGN
531
FNGDT
536
TDDFT
541
TSMGI
546
AEGTA
551
SLFVD
556
SWRAG
561
NCPAA
566
LERET
571
DPCSM
576
SQLNK
581
VCAET
586
HCSML
591
LRTGT
596
VFERC
601
HATVN
606
PAPFY
611
KRCVY
616
QACNY
621
EETFP
626
HICAA
631
LGDYV
636
HACSL
641
RGVLL
646
WGWRS
651
SVDNC
656
TIPCT
661
GNTTF
666
SYNSQ
671
ACERT
676
CLSLS
681
DRATE
686
CHHSA
691
VPVDG
696
CNCPD
701
GTYLN
706
QKGEC
711
VRKAQ
716
CPCIL
721
EGYKF
726
ILAEQ
731
STVIN
736
GITCH
741
CINGR
746
LSCPQ
751
RPQMF
756
LASCQ
761
APKTF
766
KSCSQ
771
SSENK
776
FGAAC
781
APTCQ
786
MLATG
791
VACVP
796
TKCEP
801
GCVCA
806
EGLYE
811
NADGQ
816
CVPPE
821
ECPCE
826
FSGVS
831
YPGGA
836
ELHTD
841
CRTCS
846
CSRGR
851
WACQQ
856
GTHCP
861
STCTL
866
YGEGH
871
VITFD
876
GQRFV
881
FDGNC
886
EYILA
891
TDVCG
896
VNDSQ
901
PTFKI
906
LTENV
911
ICGNS
916
GVTCS
921
RAIKI
926
FLGGL
931
SVVLA
936
DRNYT
941
VTGEE
946
PHVQL
951
GVTPG
956
ALSLV
961
VDISI
966
PGRYN
971
LTLIW
976
NRHMT
981
ILIRI
986
ARASQ
991
DPLCG
996
LCGNF
1001
NGNMK
1006
DDFET
1011
RSRYV
1016
ASSEL
1021
ELVNS
1026
WKESP
1031
LCGDV
1036
SFVTD
1041
PCSLN
1046
AFRRS
1051
WAERK
1056
CSVIN
1061
SQTFA
1066
TCHSK
1071
VYHLP
1076
YYEAC
1081
VRDAC
1086
GCDSG
1091
GDCEC
1096
LCDAV
1101
AAYAQ
1106
ACLDK
1111
GVCVD
1116
WRTPA
1121
FCPIY
1126
CGFYN
1131
THTQD
1136
GHGEY
1141
QYTQE
1146
ANCTW
1151
HYQPC
1156
LCPSQ
1161
PQSVP
1166
GSNIE
1171
GCYNC
1176
SQDEY
1181
FDHEE
1186
GVCVP
1191
CMPPT
1196
TPQPP
1201
TTPQL
1206
PTTGS
1211
RPTQV
1216
WPMTG
1221
TSTTI
1226
GLLSS
1231
TGPSP
1236
SSNHT
1241
PASPT
1246
QTPLL
1251
PATLT
1256
SSKPT
1261
ASSGE
1266
PPRPT
1271
TAVTP
1276
QATSG
1281
LPPTA
1286
TLRST
1291
ATKPT
1296
VTQAT
1301
TRATA
1306
STASP
1311
ATTST
1316
AQSTT
1321
RTTMT
1326
LPTPA
1331
TSGTS
1336
PTLPK
1341
STNQE
1346
LPGTT
1351
ATQTT
1356
GPRPT
1361
PASTT
1366
GPTTP
1371
QPGQP
1376
TRPTA
1381
TETTQ
1386
TRTTT
1391
EYTTP
1396
QTPHT
1401
THSPP
1406
TAGSP
1411
VPSTG
1416
PVTAT
1421
SFHAT
1426
TTYPT
1431
PSHPE
1436
TTLPT
1441
HVPPF
1446
STSLV
1451
TPSTH
1456
TVITP
1461
THAQM
1466
ATSAS
1471
NHSAP
1476
TGTIP
1481
PPTTL
1486
KATGS
1491
THTAP
1496
PITPT
1501
TSGTS
1506
QAHSS
1511
FSTNK
1516
TPTSL
1521
HSHTS
1526
STHHP
1531
EVTPT
1536
STTTI
1541
TPNPT
1546
STRTR
1551
TPVAH
1556
TNSAT
1561
SSRPP
1566
PPFTT
1571
HSPPT
1576
GSSPF
1581
SSTGP
1586
MTATS
1591
FKTTT
1596
TYPTP
1601
SHPQT
1606
TLPTH
1611
VPPFS
1616
TSLVT
1621
PSTHT
1626
VITPT
1631
HAQMA
1636
TSASI
1641
HSMPT
1646
GTIPP
1651
PTTLK
1656
ATGST
1661
HTAPT
1666
MTLTT
1671
SGTSQ
1676
ALSSL
1681
NTAKT
1686
STSLH
1691
SHTSS
1696
THHAE
1701
ATSTS
1706
TTNIT
1711
PNPTS
1716
TGTPP
1721
MTVTT
1726
SGTSQ
1731
SRSSF
1736
STAKT
1741
STSLH
1746
SHTSS
1751
THHPE
1756
VTSTS
1761
TTSIT
1766
PNHTS
1771
TGTRT
1776
PVAHT
1781
TSATS
1786
SRLPT
1791
PFTTH
1796
SPPTG
1801
TTPIS
1806
STGPV
1811
TATSF
1816
QTTTT
1821
YPTPS
1826
HPHTT
1831
LPTHV
1836
PSFST
1841
SLVTP
1846
STHTV
1851
IIPTH
1856
TQMAT
1861
SASIH
1866
SMPTG
1871
TIPPP
1876
TTIKA
1881
TGSTH
1886
TAPPM
1891
TPTTS
1896
GTSQS
1901
PSSFS
1906
TAKTS
1911
TSLPY
1916
HTSST
1921
HHPEV
1926
TPTST
1931
TNITP
1936
KHTST
1941
GTRTP
1946
VAHTT
1951
SASSS
1956
RLPTP
1961
FTTHS
1966
PPTGS
1971
SPFSS
1976
TGPMT
1981
ATSFQ
1986
TTTTY
1991
PTPSH
1996
PQTTL
2001
PTHVP
2006
PFSTS
2011
LVTPS
2016
THTVI
2021
ITTHT
2026
QMATS
2031
ASIHS
2036
TPTGT
2041
VPPPT
2046
TLKAT
2051
GSTHT
2056
APPMT
2061
VTTSG
2066
TSQTH
2071
SSFST
2076
ATASS
2081
SFISS
2086
SSWLP
2091
QNSSS
2096
RPPSS
2101
PITTQ
2106
LPHLS
2111
SATTP
2116
VSTTN
2121
QLSSS
2126
FSPSP
2131
SAPST
2136
VSSYV
2141
PSSHS
2146
SPQTS
2151
SPSVG
2156
TSSSF
2161
VSAPV
2166
HSTTL
2171
SSGSH
2176
SSLST
2181
HPTTA
2186
SVSAS
2191
PLFPS
2196
SPAAS
2201
TTIRA
2206
TLPHT
2211
ISSPF
2216
TLSAL
2221
LPIST
2226
VTVSP
2231
TPSSH
2236
LASST
2241
IAFPS
2246
TPRTT
2251
ASTHT
2256
APAFS
2261
SQSTT
2266
SRSTS
2271
LTTRV
2276
PTSGF
2281
VSLTS
2286
GVTGI
2291
PTSPV
2296
TNLTT
2301
RHPGP
2306
TLSPT
2311
TRFLT
2316
SSLTA
2321
HGSTP
2326
ASAPV
2331
SSLGT
2336
PTPTS
2341
PGVCS
2346
VREQQ
2351
EEITF
2356
KGCMA
2361
NVTVT
2366
RCEGA
2371
CISAA
2376
SFNII
2381
TQQVD
2386
ARCSC
2391
CRPLH
2396
SYEQQ
2401
LELPC
2406
PDPST
2411
PGRRL
2416
VLTLQ
2421
VFSHC
2426
VCSSV
2431
ACGD
2436
Mutation Information
DNA mutation:
None
Peptide Range:
1936 ~ 1960
Mut AA position:
1948 (13 in Wild Type peptide)
Alignment
Wild Type:
"TNITPKHTSTGTRTPVAHTTSASSS
||||||||||||.||||||||||||
Mutant:
TNITPKHTSTGTGTPVAHTTSASSS"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) MUC6
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay