Immunogenicity 11106
Sample ID
3678
Response
Negative
Tumor Type
Melanoma
Gene Symbol
TOPORS
Transcript ID
None
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (980 aa)
MIMAS
1
AAKEF
6
KMDNF
11
SPKAG
16
TSKLQ
21
QTVPA
26
DASPD
31
SKCPI
36
CLDRF
41
DNVSY
46
LDRCL
51
HKFCF
56
RCVQE
61
WSKNK
66
AECPL
71
CKQPF
76
DSIFH
81
SVRAE
86
DDFKE
91
YVLRP
96
SYNGS
101
FVTPD
106
RRFRY
111
RTTLT
116
RERNA
121
SVYSP
126
SGPVN
131
RRTTT
136
PPDSG
141
VLFEG
146
LGIST
151
RPRDV
156
EIPQF
161
MRQIA
166
VRRPT
171
TADER
176
SLRKI
181
QEQDI
186
INFRR
191
TLYRA
196
GARVR
201
NIEDG
206
GRYRD
211
ISAEF
216
FRRNP
221
ACLHR
226
LVPWL
231
KRELT
236
VLFGA
241
HGSLV
246
NIVQH
251
IIMSN
256
VTRYD
261
LESQA
266
FVSDL
271
RPFLL
276
NRTEH
281
FIHEF
286
ISFAR
291
SPFNM
296
AAFDQ
301
HANYD
306
CPAPS
311
YEEGS
316
HSDSS
321
VITIS
326
PDEAE
331
TQELD
336
INVAT
341
VSQAP
346
WDDET
351
PGPSY
356
SSSEQ
361
VHVTM
366
SSLLN
371
TSDSS
376
DEELV
381
TGGAT
386
SQIQG
391
VQTND
396
DLNND
401
SDDSS
406
DNCVI
411
VGFVK
416
PLAER
421
TPELV
426
ELSSD
431
SEDLG
436
SYEKM
441
ETVKT
446
QEQEQ
451
SYSSG
456
DSDVS
461
RCSSP
466
HSVLG
471
KDEQI
476
NKGHC
481
DSSTR
486
IKSKK
491
EEKRS
496
TSLSS
501
PRNLN
506
SSVRG
511
DRVYS
516
PYNHR
521
HRKRG
526
RSRSS
531
DSRSQ
536
SRSGH
541
DQKNH
546
RKHHG
551
KKRMK
556
SKRSR
561
SRESS
566
RPRGR
571
RDKKR
576
SRTRD
581
SSWSR
586
RSQTL
591
SLSSE
596
STSRS
601
RSRSS
606
DHGKR
611
RSRSR
616
NRDRY
621
YLRNN
626
YGSRY
631
KWEYT
636
YYSRN
641
KDRDG
646
YESSY
651
RRRTL
656
SRAHY
661
SRQSS
666
SPEFR
671
VQSFS
676
ERTNA
681
RKKNN
686
HSERK
691
YYYYE
696
RHRSR
701
SLSSN
706
RSRTA
711
STGTD
716
RVRNE
721
KPGGK
726
RKYKT
731
RHLEG
736
TNEVA
741
QPSRE
746
FASKA
751
KDSHY
756
QKSSS
761
KLDGN
766
YKNES
771
DTFSD
776
SRSSD
781
RETKH
786
KRRKR
791
KTRSL
796
SVEIV
801
YEGKA
806
TDTTK
811
HHKKK
816
KKKHK
821
KKHKK
826
HHGDN
831
ASRSP
836
VVITI
841
DSDSD
846
KDSEV
851
KEDTE
856
CDNSG
861
PQDPL
866
QNEFL
871
APSLE
876
PFETK
881
DVVTI
886
EAEFG
891
VLDKE
896
CDIAT
901
LSNNL
906
NNANK
911
TVDNI
916
PPLAA
921
SVEQT
926
LDVRE
931
ESTFV
936
SDLEN
941
QPSNI
946
VSLQT
951
EPSRQ
956
LPSPR
961
TSLMS
966
VCLGR
971
DCDMS
976
Mutation Information
DNA mutation:
None
Peptide Range:
661 ~ 685
Mut AA position:
673 (13 in Wild Type peptide)
Alignment
Wild Type:
"SRAHYSRQSSSPEFRVQSFSERTNA
||||||||||||.||||||||||||
Mutant:
SRAHYSRQSSSPAFRVQSFSERTNA"
Clin Cancer Res, 2017
Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 ExpressionGene Name (from Reference) TOPORS
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
ELISPOT assay