Immunogenicity 11121
Sample ID
3678
Response
Negative
Tumor Type
Melanoma
Gene Symbol
TSC2
Transcript ID
None
HLA INFO
B*44:02
TCR INFO
No TCR info found!
Full length protein sequence (1692 aa)
MECGL
1
NNRIR
6
MIGQI
11
CEVAK
16
TKKFE
21
EHAVE
26
ALWKA
31
VADLL
36
QPERP
41
LEARH
46
AVLAL
51
LKAIV
56
QGQGE
61
RLGVL
66
RALFF
71
KVIKD
76
YPSNE
81
DLHER
86
LEVFK
91
ALTDN
96
GRHIT
101
YLEEE
106
LADFV
111
LQWMD
116
VGLSS
121
EFLLV
126
LVNLV
131
KFNSC
136
YLDEY
141
IARMV
146
QMICL
151
LCVRT
156
ASSVD
161
IEVSL
166
QVLDA
171
VVCYN
176
CLPAE
181
SLPLF
186
IVTLC
191
RTINV
196
KELCE
201
PCWKL
206
MRNLL
211
GTHLG
216
HSAIY
221
NMCHL
226
MEDRA
231
YMEDA
236
PLLRG
241
AVFFV
246
GMALW
251
GAHRL
256
YSLRN
261
SPTSV
266
LPSFY
271
QAMAC
276
PNEVV
281
SYEIV
286
LSITR
291
LIKKY
296
RKELQ
301
VVAWD
306
ILLNI
311
IERLL
316
QQLQT
321
LDSPE
326
LRTIV
331
HDLLT
336
TVEEL
341
CDQNE
346
FHGSQ
351
ERYFE
356
LVERC
361
ADQRP
366
ESSLL
371
NLISY
376
RAQSI
381
HPAKD
386
GWIQN
391
LQALM
396
ERFFR
401
SESRG
406
AVRIK
411
VLDVL
416
SFVLL
421
INRQF
426
YEEEL
431
INSVV
436
ISQLS
441
HIPED
446
KDHQV
451
RKLAT
456
QLLVD
461
LAEGC
466
HTHHF
471
NSLLD
476
IIEKV
481
MARSL
486
SPPPE
491
LEERD
496
VAAYS
501
ASLED
506
VKTAV
511
LGLLV
516
ILQTK
521
LYTLP
526
ASHAT
531
RVYEM
536
LVSHI
541
QLHYK
546
HSYTL
551
PIASS
556
IRLQA
561
FDFLL
566
LLRAD
571
SLHRL
576
GLPNK
581
DGVVR
586
FSPYC
591
VCDYM
596
EPERG
601
SEKKT
606
SGPLS
611
PPTGP
616
PGPAP
621
AGPAV
626
RLGSV
631
PYSLL
636
FRVLL
641
QCLKQ
646
ESDWK
651
VLKLV
656
LGRLP
661
ESLRY
666
KVLIF
671
TSPCS
676
VDQLC
681
SALCS
686
MLSGP
691
KTLER
696
LRGAP
701
EGFSR
706
TDLHL
711
AVVPV
716
LTALI
721
SYHNY
726
LDKTK
731
QREMV
736
YCLEQ
741
GLIHR
746
CASQC
751
VVALS
756
ICSVE
761
MPDII
766
IKALP
771
VLVVK
776
LTHIS
781
ATASM
786
AVPLL
791
EFLST
796
LARLP
801
HLYRN
806
FAAEQ
811
YASVF
816
AISLP
821
YTNPS
826
KFNQY
831
IVCLA
836
HHVIA
841
MWFIR
846
CRLPF
851
RKDFV
856
PFITK
861
GLRSN
866
VLLSF
871
DDTPE
876
KDSFR
881
ARSTS
886
LNERP
891
KSRIQ
896
TSLTS
901
ASLGS
906
ADENS
911
VAQAD
916
DSLKN
921
LHLEL
926
TETCL
931
DMMAR
936
YVFSN
941
FTAVP
946
KRSPV
951
GEFLL
956
AGGRT
961
KTWLV
966
GNKLV
971
TVTTS
976
VGTGT
981
RSLLG
986
LDSGE
991
LQSGP
996
ESSSS
1001
PGVHV
1006
RQTKE
1011
APAKL
1016
ESQAG
1021
QQVSR
1026
GARDR
1031
VRSMS
1036
GGHGL
1041
RVGAL
1046
DVPAS
1051
QFLGS
1056
ATSPG
1061
PRTAP
1066
AAKPE
1071
KASAG
1076
TRVPV
1081
QEKTN
1086
LAAYV
1091
PLLTQ
1096
GWAEI
1101
LVRRP
1106
TGNTS
1111
WLMSL
1116
ENPLS
1121
PFSSD
1126
INNMP
1131
LQELS
1136
NALMA
1141
AERFK
1146
EHRDT
1151
ALYKS
1156
LSVPA
1161
ASTAK
1166
PPPLP
1171
RSNTD
1176
SAVVM
1181
EEGSP
1186
GEVPV
1191
LVEPP
1196
GLEDV
1201
EAALG
1206
MDRRT
1211
DAYSR
1216
SSSVS
1221
SQEEK
1226
SLHAE
1231
ELVGR
1236
GIPIE
1241
RVVSS
1246
EGGRP
1251
SVDLS
1256
FQPSQ
1261
PLSKS
1266
SSSPE
1271
LQTLQ
1276
DILGD
1281
PGDKA
1286
DVGRL
1291
SPEVK
1296
ARSQS
1301
GTLDG
1306
ESAAW
1311
SASGE
1316
DSRGQ
1321
PEGPL
1326
PSSSP
1331
RSPSG
1336
LRPRG
1341
YTISD
1346
SAPSR
1351
RGKRV
1356
ERDAL
1361
KSRAT
1366
ASNAE
1371
KVPGI
1376
NPSFV
1381
FLQLY
1386
HSPFF
1391
GDESN
1396
KPILL
1401
PNESQ
1406
SFERS
1411
VQLLD
1416
QIPSY
1421
DTHKI
1426
AVLYV
1431
GEGQS
1436
NSELA
1441
ILSNE
1446
HGSYR
1451
YTEFL
1456
TGLGR
1461
LIELK
1466
DCQPD
1471
KVYLG
1476
GLDVC
1481
GEDGQ
1486
FTYCW
1491
HDDIM
1496
QAVFH
1501
IATLM
1506
PTKDV
1511
DKHRC
1516
DKKRH
1521
LGNDF
1526
VSIVY
1531
NDSGE
1536
DFKLG
1541
TIKGQ
1546
FNFVH
1551
VIVTP
1556
LDYEC
1561
NLVSL
1566
QCRKD
1571
MEGLV
1576
DTSVA
1581
KIVSD
1586
RNLPF
1591
VARQM
1596
ALHAN
1601
MASQV
1606
HHSRS
1611
NPTDI
1616
YPSKW
1621
IARLR
1626
HIKRL
1631
RQRIC
1636
EEAAY
1641
SNPSL
1646
PLVHP
1651
PSHSK
1656
APAQT
1661
PAEPT
1666
PGYEV
1671
GQRKR
1676
LISSV
1681
EDFTE
1686
FV
1691
Mutation Information
DNA mutation:
None
Peptide Range:
849 ~ 873
Mut AA position:
861 (13 in Wild Type peptide)
Alignment
Wild Type:
"IRCRLPFRKDFVPFITKGLRSNVLL
||||||||||||.||||||||||||
Mutant:
IRCRLPFRKDFVLFITKGLRSNVLL"
Clin Cancer Res, 2017
Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 ExpressionGene Name (from Reference) TSC2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
ELISPOT assay