Immunogenicity 11154
Sample ID
3678
Response
Negative
Tumor Type
Melanoma
Gene Symbol
ZNF451
Transcript ID
None
HLA INFO
A*03:01
TCR INFO
No TCR info found!
Full length protein sequence (975 aa)
MGDPG
1
SEIIE
6
SVPPA
11
GPEAS
16
ESTTD
21
ENEDD
26
IQFVS
31
EGPLR
36
PVLEY
41
IDLVS
46
SDDEE
51
PSTSY
56
TDENI
61
KRKDH
66
IDYQK
71
DKVAL
76
TLARL
81
ARHVE
86
VEKQQ
91
KEEKN
96
RAFRE
101
KIDFQ
106
HAHGL
111
QELEF
116
IRGHS
121
DTEAA
126
RLCVD
131
QWLKM
136
PGLKT
141
GTINC
146
GTKSS
151
FRRGG
156
HTWVS
161
GKPIL
166
CPIMH
171
CNKEF
176
DNGHL
181
LLGHL
186
KRFDH
191
SPCDP
196
TITLH
201
GPFFS
206
SFACV
211
VCYKK
216
FVTQQ
221
QYRDH
226
LFDKE
231
ATDDG
236
HNNNL
241
LPQII
246
QCFAC
251
PNCFL
256
LFSRK
261
EECSK
266
HMSGK
271
NHFHQ
276
SFKLG
281
DNKGI
286
AHPIS
291
FPSFA
296
KKLLI
301
SLCKD
306
VPFQV
311
KCVAC
316
HKTLR
321
SHMEL
326
TAHFR
331
VHCRN
336
AGPVA
341
VAEKS
346
ITQVA
351
EKFIL
356
RGYCP
361
DCNQV
366
FVDET
371
STQNH
376
KQNSG
381
HKVRV
386
INSVE
391
ESVLL
396
YCHSS
401
EGNKD
406
PSSDL
411
HLLLD
416
QSKFS
421
SLKRT
426
MSIKE
431
SSSLE
436
CIAIP
441
KKKMN
446
LKDKS
451
HEGVA
456
CVQKE
461
KSVVK
466
TWFCE
471
CNQRF
476
PSEDA
481
VEKHV
486
FSANT
491
MGYKC
496
VVCGK
501
VCDDS
506
GVIRL
511
HMSRI
516
HGGAH
521
LNNFL
526
FWCRT
531
CKKEL
536
TRKDT
541
IMAHV
546
TEFHN
551
GHRYF
556
YEMDE
561
VEGET
566
LPSSS
571
TTLDN
576
LTANK
581
PSSAI
586
TVIDH
591
SPANS
596
SPRGK
601
WQCRI
606
CEDMF
611
DSQEY
616
VKQHC
621
MSLAS
626
HKFHR
631
YSCAH
636
CRKPF
641
HKIET
646
LYRHC
651
QDEHD
656
NEIKI
661
KYFCG
666
LCDLI
671
FNVEE
676
AFLSH
681
YEEHH
686
SIDYV
691
FVSEK
696
TETSI
701
KTEDD
706
FPVIE
711
TSNQL
716
TCGCR
721
ESYIC
726
KVNRK
731
EDYSR
736
CLQIM
741
LDKGK
746
LWFRC
751
SLCSA
756
TAQNL
761
TDMNT
766
HIHQV
771
HKEKS
776
DEEEQ
781
QYVIK
786
CGTCT
791
KAFHD
796
PESAQ
801
QHFHR
806
KHCFL
811
QKPSV
816
AHFGS
821
EKSNL
826
YKFTA
831
SASHT
836
ERKLK
841
QAINY
846
SKSLD
851
MEKGV
856
ENDLS
861
YQNIE
866
EEIVE
871
LPDLD
876
YLRTM
881
THIVF
886
VDFDN
891
WSNFF
896
GHLPG
901
HLNQG
906
TFIWG
911
FQGGN
916
TNWKP
921
PLNCK
926
IYNYL
931
NRIGC
936
FFLHP
941
RCSKR
946
KDAAD
951
FAICM
956
HNVTV
961
MITWV
966
PKILQ
971
Mutation Information
DNA mutation:
None
Peptide Range:
903 ~ 927
Mut AA position:
915 (13 in Wild Type peptide)
Alignment
Wild Type:
"LPGHLNQGTFIWGFQGGNTNWKPPL
||||||||||||.||||||||||||
Mutant:
LPGHLNQGTFIWSFQGGNTNWKPPL"
Clin Cancer Res, 2017
Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 ExpressionGene Name (from Reference) ZNF451
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
ELISPOT assay