Immunogenicity 11164
Sample ID
3678
Response
Negative
Tumor Type
Melanoma
Gene Symbol
ZNF574
Transcript ID
None
HLA INFO
B*44:02
TCR INFO
No TCR info found!
Full length protein sequence (896 aa)
MTEES
1
EETVL
6
YIEHR
11
YVCSE
16
CNQLY
21
GSLEE
26
VLMHQ
31
NSHVP
36
QQHFE
41
LVGVA
46
DPGVT
51
VATDT
56
ASGTG
61
LYQTL
66
VQESQ
71
YQCLE
76
CGQLL
81
MSPSQ
86
LLEHQ
91
ELHLK
96
MMAPQ
101
EAVPA
106
EPSPK
111
APPLS
116
SSTIH
121
YECVD
126
CKALF
131
ASQEL
136
WLNHR
141
QTHLR
146
ATPTK
151
APAPV
156
VLGSP
161
VVLGP
166
PVGQA
171
RVAVE
176
HSYRK
181
AEEGG
186
EGATV
191
PSAAA
196
TTTEV
201
VTEVE
206
LLLYK
211
CSECS
216
QLFQL
221
PADFL
226
EHQAT
231
HFPAP
236
VPESQ
241
EPALQ
246
QEVQA
251
SSPAE
256
VPVSQ
261
PDPLP
266
ASDHS
271
YELRN
276
GEAIG
281
RDRRG
286
RRARR
291
NNSGE
296
AGGAA
301
TQELF
306
CSACD
311
QLFLS
316
PHQLQ
321
QHLRS
326
HREGV
331
FKCPL
336
CSRVF
341
PSPSS
346
LDQHL
351
GDHSS
356
ESHFL
361
CVDCG
366
LAFGT
371
EALLL
376
AHRRA
381
HTPNP
386
LHSCP
391
CGKTF
396
VNLTK
401
FLYHR
406
RTHGV
411
GGVPL
416
PTTPV
421
PPEEP
426
VIGFP
431
EPAPA
436
ETGEP
441
EAPEP
446
PVSEE
451
TSAGP
456
AAPGT
461
YRCLL
466
CSREF
471
GKALQ
476
LTRHQ
481
RFVHR
486
LERRH
491
KCSIC
496
GKMFK
501
KKSHV
506
RNHLR
511
THTGE
516
RPFPC
521
PDCSK
526
PFNSP
531
ANLAR
536
HRLTH
541
TGERP
546
YRCGD
551
CGKAF
556
TQSST
561
LRQHR
566
LVHAQ
571
HFPYR
576
CQECG
581
VRFHR
586
PYRLL
591
MHRYH
596
HTGEY
601
PYKCR
606
ECPRS
611
FLLRR
616
LLEVH
621
QLVVH
626
AGRQP
631
HRCPS
636
CGAAF
641
PSSLR
646
LREHR
651
CAAAA
656
AQAPR
661
RFECG
666
TCGKK
671
VGSAA
676
RLQAH
681
EAAHA
686
AAGPG
691
EVLAK
696
EPPAP
701
RAPRA
706
TRAPV
711
ASPAA
716
LGSTA
721
TASPA
726
APARR
731
RGLEC
736
SECKK
741
LFSTE
746
TSLQV
751
HRRIH
756
TGERP
761
YPCPD
766
CGKAF
771
RQSTH
776
LKDHR
781
RLHTG
786
ERPFA
791
CEVCG
796
KAFAI
801
SMRLA
806
EHRRI
811
HTGER
816
PYSCP
821
DCGKS
826
YRSFS
831
NLWKH
836
RKTHQ
841
QQHQA
846
AVRQQ
851
LAEAE
856
AAVGL
861
AVMET
866
AVEAL
871
PLVEA
876
IEIYP
881
LAEAE
886
GVQIS
891
G
896
Mutation Information
DNA mutation:
None
Peptide Range:
232 ~ 256
Mut AA position:
244 (13 in Wild Type peptide)
Alignment
Wild Type:
"HQATHFPAPVPESQEPALQQEVQAS
||||||||||||.||||||||||||
Mutant:
HQATHFPAPVPEFQEPALQQEVQAS"
Clin Cancer Res, 2017
Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 ExpressionGene Name (from Reference) ZNF574
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
ELISPOT assay