Immunogenicity 11186
Sample ID
3716
Response
Negative
Tumor Type
Melanoma
Gene Symbol
ALPK1
Transcript ID
None
HLA INFO
B*15:01
TCR INFO
No TCR info found!
Full length protein sequence (1037 aa)
MWYEA
1
AELIW
6
ASIVG
11
YLALP
16
QPDKK
21
GLSTS
26
LGILA
31
DIFVS
36
MSKND
41
YEKFK
46
NNPQI
51
NLSLL
56
KEFDH
61
HLLSA
66
AEACK
71
LAAAF
76
SAYTP
81
LFVLT
86
AVNIR
91
GTCLL
96
SYSSS
101
NDCPP
106
ELKNL
111
HLCEA
116
KEAFE
121
IGLLT
126
KRDDE
131
PVTGK
136
QELHS
141
FVKAA
146
FGLTT
151
VHRRL
156
HGETG
161
TVHAA
166
SQLCK
171
EAMGK
176
LYNFS
181
TSSRS
186
QDREA
191
LSQEV
196
MSVIA
201
QVKEH
206
LQVQS
211
FSNVD
216
DRSYV
221
PESFE
226
CRLDK
231
LILHG
236
QGDFQ
241
KILDT
246
YSQHH
251
TSVCE
256
VFESD
261
CGNNK
266
NEQKD
271
AKTGV
276
CITAL
281
KTEIK
286
NIDTV
291
STTQE
296
KPHCQ
301
RDTGI
306
SSSLM
311
GKNVQ
316
RELRR
321
GGRRN
326
WTHSD
331
AFRVS
336
LDQDV
341
ETETE
346
PSDYS
351
NGEGA
356
VFNKS
361
LSGSQ
366
TSSAW
371
SNLSG
376
FSSSA
381
SWEEV
386
NYHVD
391
DRSAR
396
KEPGK
401
EHLVD
406
TQCST
411
ALSEE
416
LENDR
421
EGRAM
426
HSLHS
431
QLHDL
436
SLQEP
441
NNDNL
446
EPSQN
451
QPQQQ
456
MPLTP
461
FSPHN
466
TPGIF
471
LAPGA
476
GLLEG
481
APEGI
486
QEVRN
491
MGPRN
496
TSAHS
501
RPSYR
506
SASWS
511
SDSGR
516
PKNMG
521
THPSV
526
QKEEA
531
FEIIV
536
EFPET
541
NCDVK
546
DRQGK
551
EQGEE
556
ISERG
561
AGPTF
566
KASPS
571
WVDPE
576
GETAE
581
STEDA
586
PLDFH
591
RVLHN
596
SLGNI
601
SMLPC
606
SSFTP
611
NWPVQ
616
NPDSR
621
KSGGP
626
VAEQG
631
IDPDA
636
STVDE
641
EGQLL
646
DSMDV
651
PCTNG
656
HGSHR
661
LCILR
666
QPPGQ
671
RAETP
676
NSSVS
681
GNILF
686
PVLSE
691
DCTTT
696
EEGNQ
701
PGNML
706
NCSQN
711
SSSSS
716
VWWLK
721
SPAFS
726
SGSSE
731
GDSPW
736
SYLNS
741
SGSSW
746
VSLPG
751
KMRKE
756
ILEAR
761
TLQPD
766
DFEKL
771
LAGVR
776
HDWLF
781
QRLEN
786
TGVFK
791
PSQLH
796
RAHSA
801
LLLKY
806
SKKSE
811
LWTAQ
816
ETIVY
821
LGDYL
826
TVKKK
831
GRQRN
836
AFWVH
841
HLHQE
846
EILGR
851
YVGKD
856
YKEQK
861
GLWHH
866
FTDVE
871
RQMTA
876
QHYVT
881
EFNKR
886
LYEQN
891
IPTQI
896
FYIPS
901
TILLI
906
LEDKT
911
IKGCI
916
SVEPY
921
ILGEF
926
VKLSN
931
NTKVV
936
KTEYK
941
ATEYG
946
LAYGH
951
FSYEF
956
SNHRD
961
VVVDL
966
QGWVT
971
GNGKG
976
LIYLT
981
DPQIH
986
SVDQK
991
VFTTN
996
FGKRG
1001
IFYFF
1006
NNQHV
1011
ECNEI
1016
CHRLS
1021
LTRPS
1026
MEKPC
1031
KS
1036
Mutation Information
DNA mutation:
None
Peptide Range:
597 ~ 621
Mut AA position:
None (None in Wild Type peptide)
Alignment
Wild Type:
"VLHNSLGNISMLPCSSFTPNWPVQN
||||||||||||.||||||||||||
Mutant:
VLHNSLGNISMLQCSSFTPNWPVQN"
Clin Cancer Res, 2017
Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 ExpressionGene Name (from Reference) ALPK1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
ELISPOT assay