Immunogenicity 11197

summary
Sample ID
3716
Response
Negative
Tumor Type
Melanoma
Gene Symbol
HERC2
Transcript ID
None
HLA INFO
B*15:01
TCR INFO

No TCR info found!

T cell Tumor cell B*15:01
sequence
Full length protein sequence (4829 aa)
MPSES
1
FCLAA
6
QARLD
11
SKWLK
16
TDIQL
21
AFTRD
26
GLCGL
31
WNEMV
36
KDGEI
41
VYTGT
46
ESTQN
51
GELPP
56
RKDDS
61
VEPSG
66
TKKED
71
LNDKE
76
KKDEE
81
ETPAP
86
IYRAK
91
SILDS
96
WVWGK
101
QPDVN
106
ELKEC
111
LSVLV
116
KEQQA
121
LAVQS
126
ATTTL
131
SALRL
136
KQRLV
141
ILERY
146
FIALN
151
RTVFQ
156
ENVKV
161
KWKSS
166
GISLP
171
PVDKK
176
SSRPA
181
GKGVE
186
GLARV
191
GSRAA
196
LSFAF
201
AFLRR
206
AWRSG
211
EDADL
216
CSELL
221
QESLD
226
ALRAL
231
PEASL
236
FDEST
241
VSSVW
246
LEVVE
251
RATRF
256
LRSVV
261
TGDVH
266
GTPAT
271
KGPGS
276
IPLQD
281
QHLAL
286
AILLE
291
LAVQR
296
GTLSQ
301
MLSAI
306
LLLLQ
311
LWDSG
316
AQETD
321
NERSA
326
QGTSA
331
PLLPL
336
LQRFQ
341
SIICR
346
KDAPH
351
SEGDM
356
HLLSG
361
PLSPN
366
ESFLR
371
YLTLP
376
QDNEL
381
AIDLR
386
QTAVV
391
VMAHL
396
DRLAT
401
PCMPP
406
LCSSP
411
TSHKG
416
SLQEV
421
IGWGL
426
IGWKY
431
YANVI
436
GPIQC
441
EGLAN
446
LGVTQ
451
IACAE
456
KRFLI
461
LSRNG
466
RVYTQ
471
AYNSD
476
TLAPQ
481
LVQGL
486
ASRNI
491
VKIAA
496
HSDGH
501
HYLAL
506
AATGE
511
VYSWG
516
CGDGG
521
RLGHG
526
DTVPL
531
EEPKV
536
ISAFS
541
GKQAG
546
KHVVH
551
IACGS
556
TYSAA
561
ITAEG
566
ELYTW
571
GRGNY
576
GRLGH
581
GSSED
586
EAIPM
591
LVAGL
596
KGLKV
601
IDVAC
606
GSGDA
611
QTLAV
616
TENGQ
621
VWSWG
626
DGDYG
631
KLGRG
636
GSDGC
641
KTPKL
646
IEKLQ
651
DLDVV
656
KVRCG
661
SQFSI
666
ALTKD
671
GQVYS
676
WGKGD
681
NQRLG
686
HGTEE
691
HVRYP
696
KLLEG
701
LQGKK
706
VIDVA
711
AGSTH
716
CLALT
721
EDSEV
726
HSWGS
731
NDQCQ
736
HFDTL
741
RVTKP
746
EPAAL
751
PGLDT
756
KHIVG
761
IACGP
766
AQSFA
771
WSSCS
776
EWSIG
781
LRVPF
786
VVDIC
791
SMTFE
796
QLDLL
801
LRQVS
806
EGMDG
811
SADWP
816
PPQEK
821
ECVAV
826
ATLNL
831
LRLQL
836
HAAIS
841
HQVDP
846
EFLGL
851
GLGSI
856
LLNSL
861
KQTVV
866
TLASS
871
AGVLS
876
TVQSA
881
AQAVL
886
QSGWS
891
VLLPT
896
AEERA
901
RALSA
906
LLPCA
911
VSGNE
916
VNISP
921
GRRFM
926
IDLLV
931
GSLMA
936
DGGLE
941
SALHA
946
AITAE
951
IQDIE
956
AKKEA
961
QKEKE
966
IDEQE
971
ANAST
976
FHRSR
981
TPLDK
986
DLINT
991
GICES
996
SGKQC
1001
LPLVQ
1006
LIQQL
1011
LRNIA
1016
SQTVA
1021
RLKDV
1026
ARRIS
1031
SCLDF
1036
EQHSR
1041
ERSAS
1046
LDLLL
1051
RFQRL
1056
LISKL
1061
YPGES
1066
IGQTS
1071
DISSP
1076
ELMGV
1081
GSLLK
1086
KYTAL
1091
LCTHI
1096
GDILP
1101
VAASI
1106
ASTSW
1111
RHFAE
1116
VAYIV
1121
EGDFT
1126
GVLLP
1131
ELVVS
1136
IVLLL
1141
SKNAG
1146
LMQEA
1151
GAVPL
1156
LGGLL
1161
EHLDR
1166
FNHLA
1171
PGKER
1176
DDHEE
1181
LAWPG
1186
IMGQN
1191
CRNNE
1196
EVTLI
1201
RKADL
1206
ENHNK
1211
DGGFW
1216
TVIDG
1221
KVYDI
1226
KDFQT
1231
QSLTG
1236
NSILA
1241
QFAGE
1246
DPVVA
1251
LEAAL
1256
QFEDT
1261
RESMH
1266
AFCVG
1271
QYLEP
1276
DQEIV
1281
TIPDL
1286
GSLSS
1291
PLIDT
1296
ERNLG
1301
LLLGL
1306
HASYL
1311
AMSTP
1316
LSPVE
1321
IECAK
1326
WLQSS
1331
IFSGG
1336
LQTSQ
1341
IHYSY
1346
NEEKD
1351
EDHCS
1356
SPGGT
1361
PASKS
1366
RLCSH
1371
RRALG
1376
DHSQA
1381
FLQAI
1386
ADNNI
1391
QDHNV
1396
KDFLC
1401
QIERY
1406
CRQCH
1411
LTTPI
1416
MFPPE
1421
HPVEE
1426
VGRLL
1431
LCCLL
1436
KHEDL
1441
GHVAL
1446
SLVHA
1451
GALGI
1456
EQVKH
1461
RTLPK
1466
SVVDV
1471
CRVVY
1476
QAKCS
1481
LIKTH
1486
QEQGR
1491
SYKEV
1496
CAPVI
1501
ERLRF
1506
LFNEL
1511
RPAVC
1516
NDLSI
1521
MSKFK
1526
LLSSL
1531
PRWRR
1536
IAQKI
1541
IRERR
1546
KKRVP
1551
KKPES
1556
TDDEE
1561
KIGNE
1566
ESDLE
1571
EACIL
1576
PHSPI
1581
NVDKR
1586
PIAIK
1591
SPKDK
1596
WQPLL
1601
STVTG
1606
VHKYK
1611
WLKQN
1616
VQGLY
1621
PQSPL
1626
LSTIA
1631
EFALK
1636
EEPVD
1641
VEKMR
1646
KCLLK
1651
QLERA
1656
EVRLE
1661
GIDTI
1666
LKLAS
1671
KNFLL
1676
PSVQY
1681
AMFCG
1686
WQRLI
1691
PEGID
1696
IGEPL
1701
TDCLK
1706
DVDLI
1711
PPFNR
1716
MLLEV
1721
TFGKL
1726
YAWAV
1731
QNIRN
1736
VLMDA
1741
SAKFK
1746
ELGIQ
1751
PVPLQ
1756
TITNE
1761
NPSGP
1766
SLGTI
1771
PQARF
1776
LLVML
1781
SMLTL
1786
QHGAN
1791
NLDLL
1796
LNSGM
1801
LALTQ
1806
TALRL
1811
IGPSC
1816
DNVEE
1821
DMNAS
1826
AQGAS
1831
ATVLE
1836
ETRKE
1841
TAPVQ
1846
LPVSG
1851
PELAA
1856
MMKIG
1861
TRVMR
1866
GVDWK
1871
WGDQD
1876
GPPPG
1881
LGRVI
1886
GELGE
1891
DGWIR
1896
VQWDT
1901
GSTNS
1906
YRMGK
1911
EGKYD
1916
LKLAE
1921
LPAAA
1926
QPSAE
1931
DSDTE
1936
DDSEA
1941
EQTER
1946
NIHPT
1951
AMMFT
1956
STINL
1961
LQTLC
1966
LSAGV
1971
HAEIM
1976
QSEAT
1981
KTLCG
1986
LLRML
1991
VESGT
1996
TDKTS
2001
SPNRL
2006
VYREQ
2011
HRSWC
2016
TLGFV
2021
RSIAL
2026
TPQVC
2031
GALSS
2036
PQWIT
2041
LLMKV
2046
VEGHA
2051
PFTAT
2056
SLQRQ
2061
ILAVH
2066
LLQAV
2071
LPSWD
2076
KTERA
2081
RDMKC
2086
LVEKL
2091
FDFLG
2096
SLLTT
2101
CSSDV
2106
PLLRE
2111
STLRR
2116
RRVRP
2121
QASLT
2126
ATHSS
2131
TLAEE
2136
VVALL
2141
RTLHS
2146
LTQWN
2151
GLINK
2156
YINSQ
2161
LRSIT
2166
HSFVG
2171
RPSEG
2176
AQLED
2181
YFPDS
2186
ENPEV
2191
GGLMA
2196
VLAVI
2201
GGIDG
2206
RLRLG
2211
GQVMH
2216
DEFGE
2221
GTVTR
2226
ITPKG
2231
KITVQ
2236
FSDMR
2241
TCRVC
2246
PLNQL
2251
KPLPA
2256
VAFNV
2261
NNLPF
2266
TEPML
2271
SVWAQ
2276
LVNLA
2281
GSKLE
2286
KHKIK
2291
KSTKQ
2296
AFAGQ
2301
VDLDL
2306
LRCQQ
2311
LKLYI
2316
LKAGR
2321
ALLSH
2326
QDKLR
2331
QILSQ
2336
PAVQE
2341
TGTVH
2346
TDDGA
2351
VVSPD
2356
LGDMS
2361
PEGPQ
2366
PPMIL
2371
LQQLL
2376
ASATQ
2381
PSPVK
2386
AIFDK
2391
QELEA
2396
AALAV
2401
CQCLA
2406
VESTH
2411
PSSPG
2416
FEDCS
2421
SSEAT
2426
TPVAV
2431
QHIRP
2436
ARVKR
2441
RKQSP
2446
VPALP
2451
IVVQL
2456
MEMGF
2461
SRRNI
2466
EFALK
2471
SLTGA
2476
SGNAS
2481
SLPGV
2486
EALVG
2491
WLLDH
2496
SDIQV
2501
TELSD
2506
ADTVS
2511
DEYSD
2516
EEVVE
2521
DVDDA
2526
AYSMS
2531
TGAVV
2536
TESQT
2541
YKKRA
2546
DFLSN
2551
DDYAV
2556
YVREN
2561
IQVGM
2566
MVRCC
2571
RAYEE
2576
VCEGD
2581
VGKVI
2586
KLDRD
2591
GLHDL
2596
NVQCD
2601
WQQKG
2606
GTYWV
2611
RYIHV
2616
ELIGY
2621
PPPSS
2626
SSHIK
2631
IGDKV
2636
RVKAS
2641
VTTPK
2646
YKWGS
2651
VTHQS
2656
VGVVK
2661
AFSAN
2666
GKDII
2671
VDFPQ
2676
QSHWT
2681
GLLSE
2686
MELVP
2691
SIHPG
2696
VTCDG
2701
CQMFP
2706
INGSR
2711
FKCRN
2716
CDDFD
2721
FCETC
2726
FKTKK
2731
HNTRH
2736
TFGRI
2741
NEPGQ
2746
SAVFC
2751
GRSGK
2756
QLKRC
2761
HSSQP
2766
GMLLD
2771
SWSRM
2776
VKSLN
2781
VSSSV
2786
NQASR
2791
LIDGS
2796
EPCWQ
2801
SSGSQ
2806
GKHWI
2811
RLEIF
2816
PDVLV
2821
HRLKM
2826
IVDPA
2831
DSSYM
2836
PSLVV
2841
VSGGN
2846
SLNNL
2851
IELKT
2856
ININP
2861
SDTTV
2866
PLLND
2871
CTEYH
2876
RYIEI
2881
AIKQC
2886
RSSGI
2891
DCKIH
2896
GLILL
2901
GRIRA
2906
EEEDL
2911
AAVPF
2916
LASDN
2921
EEEED
2926
EKGNS
2931
GSLIR
2936
KKAAG
2941
LESAA
2946
TIRTK
2951
VFVWG
2956
LNDKD
2961
QLGGL
2966
KGSKI
2971
KVPSF
2976
SETLS
2981
ALNVV
2986
QVAGG
2991
SKSLF
2996
AVTVE
3001
GKVYA
3006
CGEAT
3011
NGRLG
3016
LGISS
3021
GTVPI
3026
PRQIT
3031
ALSSY
3036
VVKKV
3041
AVHSG
3046
GRHAT
3051
ALTVD
3056
GKVFS
3061
WGEGD
3066
DGKLG
3071
HFSRM
3076
NCDKP
3081
RLIEA
3086
LKTKR
3091
IRDIA
3096
CGSSH
3101
SAALT
3106
SSGEL
3111
YTWGL
3116
GEYGR
3121
LGHGD
3126
NTTQL
3131
KPKMV
3136
KVLLG
3141
HRVIQ
3146
VACGS
3151
RDAQT
3156
LALTD
3161
EGLVF
3166
SWGDG
3171
DFGKL
3176
GRGGS
3181
EGCNI
3186
PQNIE
3191
RLNGQ
3196
GVCQI
3201
ECGAQ
3206
FSLAL
3211
TKSGV
3216
VWTWG
3221
KGDYF
3226
RLGHG
3231
SDVHV
3236
RKPQV
3241
VEGLR
3246
GKKIV
3251
HVAVG
3256
ALHCL
3261
AVTDS
3266
GQVYA
3271
WGDND
3276
HGQQG
3281
NGTTT
3286
VNRKP
3291
TLVQG
3296
LEGQK
3301
ITRVA
3306
CGSSH
3311
SVAWT
3316
TVDVA
3321
TPSVH
3326
EPVLF
3331
QTARD
3336
PLGAS
3341
YLGVP
3346
SDADS
3351
SAASN
3356
KISGA
3361
SNSKP
3366
NRPSL
3371
AKILL
3376
SLDGN
3381
LAKQQ
3386
ALSHI
3391
LTALQ
3396
IMYAR
3401
DAVVG
3406
ALMPA
3411
AMIAP
3416
VECPS
3421
FSSAA
3426
PSDAS
3431
AMASP
3436
MNGEE
3441
CMLAV
3446
DIEDR
3451
LSPNP
3456
WQEKR
3461
EIVSS
3466
EDAVT
3471
PSAVT
3476
PSAPS
3481
ASARP
3486
FIPVT
3491
DDLGA
3496
ASIIA
3501
ETMTK
3506
TKEDV
3511
ESQNK
3516
AAGPE
3521
PQALD
3526
EFTSL
3531
LIADD
3536
TRVVV
3541
DLLKL
3546
SVCSR
3551
AGDRG
3556
RDVLS
3561
AVLSG
3566
MGTAY
3571
PQVAD
3576
MLLEL
3581
CVTEL
3586
EDVAT
3591
DSQSG
3596
RLSSQ
3601
PVVVE
3606
SSHPY
3611
TDDTS
3616
TSGTV
3621
KIPGA
3626
EGLRV
3631
EFDRQ
3636
CSTER
3641
RHDPL
3646
TVMDG
3651
VNRIV
3656
SVRSG
3661
REWSD
3666
WSSEL
3671
RIPGD
3676
ELKWK
3681
FISDG
3686
SVNGW
3691
GWRFT
3696
VYPIM
3701
PAAGP
3706
KELLS
3711
DRCVL
3716
SCPSM
3721
DLVTC
3726
LLDFR
3731
LNLAS
3736
NRSIV
3741
PRLAA
3746
SLAAC
3751
AQLSA
3756
LAASH
3761
RMWAL
3766
QRLRK
3771
LLTTE
3776
FGQSI
3781
NINRL
3786
LGEND
3791
GETRA
3796
LSFTG
3801
SALAA
3806
LVKGL
3811
PEALQ
3816
RQFEY
3821
EDPIV
3826
RGGKQ
3831
LLHSP
3836
FFKVL
3841
VALAC
3846
DLELD
3851
TLPCC
3856
AETHK
3861
WAWFR
3866
RYCMA
3871
SRVAV
3876
ALDKR
3881
TPLPR
3886
LFLDE
3891
VAKKI
3896
RELMA
3901
DSENM
3906
DVLHE
3911
SHDIF
3916
KREQD
3921
EQLVQ
3926
WMNRR
3931
PDDWT
3936
LSAGG
3941
SGTIY
3946
GWGHN
3951
HRGQL
3956
GGIEG
3961
AKVKV
3966
PTPCE
3971
ALATL
3976
RPVQL
3981
IGGEQ
3986
TLFAV
3991
TADGK
3996
LYATG
4001
YGAGG
4006
RLGIG
4011
GTESV
4016
STPTL
4021
LESIQ
4026
HVFIK
4031
KVAVN
4036
SGGKH
4041
CLALS
4046
SEGEV
4051
YSWGE
4056
AEDGK
4061
LGHGN
4066
RSPCD
4071
RPRVI
4076
ESLRG
4081
IEVVD
4086
VAAGG
4091
AHSAC
4096
VTAAG
4101
DLYTW
4106
GKGRY
4111
GRLGH
4116
SDSED
4121
QLKPK
4126
LVEAL
4131
QGHRV
4136
VDIAC
4141
GSGDA
4146
QTLCL
4151
TDDDT
4156
VWSWG
4161
DGDYG
4166
KLGRG
4171
GSDGC
4176
KVPMK
4181
IDSLT
4186
GLGVV
4191
KVECG
4196
SQFSV
4201
ALTKS
4206
GAVYT
4211
WGKGD
4216
YHRLG
4221
HGSDD
4226
HVRRP
4231
RQVQG
4236
LQGKK
4241
VIAIA
4246
TGSLH
4251
CVCCT
4256
EDGEV
4261
YTWGD
4266
NDEGQ
4271
LGDGT
4276
TNAIQ
4281
RPRLV
4286
AALQG
4291
KKVNR
4296
VACGS
4301
AHTLA
4306
WSTSK
4311
PASAG
4316
KLPAQ
4321
VPMEY
4326
NHLQE
4331
IPIIA
4336
LRNRL
4341
LLLHH
4346
LSELF
4351
CPCIP
4356
MFDLE
4361
GSLDE
4366
TGLGP
4371
SVGFD
4376
TLRGI
4381
LISQG
4386
KEAAF
4391
RKVVQ
4396
ATMVR
4401
DRQHG
4406
PVVEL
4411
NRIQV
4416
KRSRS
4421
KGGLA
4426
GPDGT
4431
KSVFG
4436
QMCAK
4441
MSSFG
4446
PDSLL
4451
LPHRV
4456
WKVKF
4461
VGESV
4466
DDCGG
4471
GYSES
4476
IAEIC
4481
EELQN
4486
GLTPL
4491
LIVTP
4496
NGRDE
4501
SGANR
4506
DCYLL
4511
SPAAR
4516
APVHS
4521
SMFRF
4526
LGVLL
4531
GIAIR
4536
TGSPL
4541
SLNLA
4546
EPVWK
4551
QLAGM
4556
SLTIA
4561
DLSEV
4566
DKDFI
4571
PGLMY
4576
IRDNE
4581
ATSEE
4586
FEAMS
4591
LPFTV
4596
PSASG
4601
QDIQL
4606
SSKHT
4611
HITLD
4616
NRAEY
4621
VRLAI
4626
NYRLH
4631
EFDEQ
4636
VAAVR
4641
EGMAR
4646
VVPVP
4651
LLSLF
4656
TGYEL
4661
ETMVC
4666
GSPDI
4671
PLHLL
4676
KSVAT
4681
YKGIE
4686
PSASL
4691
IQWFW
4696
EVMES
4701
FSNTE
4706
RSLFL
4711
RFVWG
4716
RTRLP
4721
RTIAD
4726
FRGRD
4731
FVIQV
4736
LDKYN
4741
PPDHF
4746
LPESY
4751
TCFFL
4756
LKLPR
4761
YSCKQ
4766
VLEEK
4771
LKYAI
4776
HFCKS
4781
IDTDD
4786
YARIA
4791
LTGEP
4796
AADDS
4801
SDDSD
4806
NEDVD
4811
SFASD
4816
STQDY
4821
LTGH
4826
Mutation Information
DNA mutation:
None
Peptide Range:
290 ~ 314
Mut AA position:
302 (13 in Wild Type peptide)
Alignment
Wild Type:
"LAILLELAVQRGTLSQMLSAILLLL
||||||||||||.||||||||||||
Mutant:
LAILLELAVQRGMLSQMLSAILLLL"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

ELISPOT assay