Immunogenicity 11205
Sample ID
3716
Response
Negative
Tumor Type
Melanoma
Gene Symbol
MKRN3
Transcript ID
None
HLA INFO
B*15:01
TCR INFO
No TCR info found!
Full length protein sequence (507 aa)
MEEPA
1
APSEA
6
HEAAG
11
AQAGA
16
EAARE
21
GVSGP
26
DLPVC
31
EPSGE
36
SAAPD
41
SALPH
46
AARGW
51
APFPV
56
APVPA
61
HLRRG
66
GLRPA
71
PASGG
76
GAWPS
81
PLPSR
86
SSGIW
91
TKQII
96
CRYYI
101
HGQCK
106
EGENC
111
RYSHD
116
LSGRK
121
MATEG
126
GVSPP
131
GASAG
136
GGPST
141
AAHIE
146
PPTQE
151
VAEAP
156
PAASS
161
LSLPV
166
IGSAA
171
ERGFF
176
EAERD
181
NADRG
186
AAGGA
191
GVESW
196
ADAIE
201
FVPGQ
206
PYRGR
211
WVASA
216
PEAPL
221
QSSET
226
ERKQM
231
AVGSG
236
LRFCY
241
YASRG
246
VCFRG
251
ESCMY
256
LHGDI
261
CDMCG
266
LQTLH
271
PMDAA
276
QREEH
281
MRACI
286
EAHEK
291
DMELS
296
FAVQR
301
GMDKV
306
CGICM
311
EVVYE
316
KANPN
321
DRRFG
326
ILSNC
331
NHSFC
336
IRCIR
341
RWRSA
346
RQFEN
351
RIVKS
356
CPQCR
361
VTSEL
366
VIPSE
371
FWVEE
376
EEEKQ
381
KLIQQ
386
YKEAM
391
SNKAC
396
RYFAE
401
GRGNC
406
PFGDT
411
CFYKH
416
EYPEG
421
WGDEP
426
PGPGG
431
GSFSA
436
YWHQL
441
VEPVR
446
MGEGN
451
MLYKS
456
IKKEL
461
VVLRL
466
ASLLF
471
KRFLS
476
LRDEL
481
PFSED
486
QWDLL
491
HYELE
496
EYFNL
501
IL
506
Mutation Information
DNA mutation:
None
Peptide Range:
132 ~ 156
Mut AA position:
144 (13 in Wild Type peptide)
Alignment
Wild Type:
"VSPPGASAGGGPSTAAHIEPPTQEV
||||||||||||.||||||||||||
Mutant:
VSPPGASAGGGPNTAAHIEPPTQEV"
Clin Cancer Res, 2017
Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 ExpressionGene Name (from Reference) MKRN3
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
ELISPOT assay