Immunogenicity 11214
Sample ID
3716
Response
Negative
Tumor Type
Melanoma
Gene Symbol
SEC23B
Transcript ID
None
HLA INFO
B*15:01
TCR INFO
No TCR info found!
Full length protein sequence (767 aa)
MATYL
1
EFIQQ
6
NEERD
11
GVRFS
16
WNVWP
21
SSRLE
26
ATRMV
31
VPLAC
36
LLTPL
41
KERPD
46
LPPVQ
51
YEPVL
56
CSRPT
61
CKAVL
66
NPLCQ
71
VDYRA
76
KLWAC
81
NFCFQ
86
RNQFP
91
PAYGG
96
ISEVN
101
QPAEL
106
MPQFS
111
TIEYV
116
IQRGA
121
QSPLI
126
FLYVV
131
DTCLE
136
EDDLQ
141
ALKES
146
LQMSL
151
SLLPP
156
DALVG
161
LITFG
166
RMVQV
171
HELSC
176
EGISK
181
SYVFR
186
GTKDL
191
TAKQI
196
QDMLG
201
LTKPA
206
MPMQQ
211
ARPAQ
216
PQEHP
221
FASSR
226
FLQPV
231
HKIDM
236
NLTDL
241
LGELQ
246
RDPWP
251
VTQGK
256
RPLRS
261
TGVAL
266
SIAVG
271
LLEGT
276
FPNTG
281
ARIML
286
FTGGP
291
PTQGP
296
GMVVG
301
DELKI
306
PIRSW
311
HDIEK
316
DNARF
321
MKKAT
326
KHYEM
331
LANRT
336
AANGH
341
CIDIY
346
ACALD
351
QTGLL
356
EMKCC
361
ANLTG
366
GYMVM
371
GDSFN
376
TSLFK
381
QTFQR
386
IFTKD
391
FNGDF
396
RMAFG
401
ATLDV
406
KTSRE
411
LKIAG
416
AIGPC
421
VSLNV
426
KGPCV
431
SENEL
436
GVGGT
441
SQWKI
446
CGLDP
451
TSTLG
456
IYFEV
461
VNQHN
466
TPIPQ
471
GGRGA
476
IQFVT
481
HYQHS
486
STQRR
491
IRVTT
496
IARNW
501
ADVQS
506
QLRHI
511
EAAFD
516
QEAAA
521
VLMAR
526
LGVFR
531
AESEE
536
GPDVL
541
RWLDR
546
QLIRL
551
CQKFG
556
QYNKE
561
DPTSF
566
RLSDS
571
FSLYP
576
QFMFH
581
LRRSP
586
FLQVF
591
NNSPD
596
ESSYY
601
RHHFA
606
RQDLT
611
QSLIM
616
IQPIL
621
YSYSF
626
HGPPE
631
PVLLD
636
SSSIL
641
ADRIL
646
LMDTF
651
FQIVI
656
YLGET
661
IAQWR
666
KAGYQ
671
DMPEY
676
ENFKH
681
LLQAP
686
LDDAQ
691
EILQA
696
RFPMP
701
RYINT
706
EHGGS
711
QARFL
716
LSKVN
721
PSQTH
726
NNLYA
731
WGQET
736
GAPIL
741
TDDVS
746
LQVFM
751
DHLKK
756
LAVSS
761
AC
766
Mutation Information
DNA mutation:
None
Peptide Range:
96 ~ 120
Mut AA position:
108 (13 in Wild Type peptide)
Alignment
Wild Type:
"PAYGGISEVNQPAELMPQFSTIEYV
||||||||||||.||||||||||||
Mutant:
PAYGGISEVNQPVELMPQFSTIEYV"
Clin Cancer Res, 2017
Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 ExpressionGene Name (from Reference) SEC23B
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
ELISPOT assay