Immunogenicity 11220
Sample ID
3716
Response
Negative
Tumor Type
Melanoma
Gene Symbol
VPS13A
Transcript ID
None
HLA INFO
B*15:01
TCR INFO
No TCR info found!
Full length protein sequence (3135 aa)
MVFES
1
VVVDV
6
LNRFL
11
GDYVV
16
DLDTS
21
QLSLG
26
IWKGA
31
VALKN
36
LQIKE
41
NALSQ
46
LDVPF
51
KVKVG
56
HIGNL
61
KLIIP
66
WKNLY
71
TQPVE
76
AVLEE
81
IYLLI
86
VPSSR
91
IKYDP
96
LKEEK
101
QLMEA
106
KQQEL
111
KRIEE
116
AKQKV
121
VDQEQ
126
HLPEK
131
QDTFA
136
EKLVT
141
QIIKN
146
LQVKI
151
SSIHI
156
RYEDD
161
ITNRD
166
KPLSF
171
GISLQ
176
NLSMQ
181
TTDQY
186
WVPCL
191
HDETE
196
KLVRK
201
LIRLD
206
NLFAY
211
WNVKS
216
QMFYL
221
SDYDN
226
SLDDL
231
KNGIV
236
NENIV
241
PEGYD
246
FVFRP
251
ISANA
256
KLVMN
261
RRSDF
266
DFSAP
271
KINLE
276
IELHN
281
IAIEF
286
NKPQY
291
FSIME
296
LLESV
301
DMMAQ
306
NLPYR
311
KFKPD
316
VPLHH
321
HAREW
326
WAYAI
331
HGVLE
336
VNVCP
341
RLWMW
346
SWKHI
351
RKHRQ
356
KVKQY
361
KELYK
366
KKLTS
371
KKPPG
376
ELLVS
381
LEELE
386
KTLDV
391
FNITI
396
ARQTA
401
EVEVK
406
KAGYK
411
IYKEG
416
VKDPE
421
DNKGW
426
FSWLW
431
SWSEQ
436
NTNEQ
441
QPDVQ
446
PETLE
451
EMLTP
456
EEKAL
461
LYEAI
466
GYSET
471
AVDPT
476
LLKTF
481
EALKF
486
FVHLK
491
SMSIV
496
LRENH
501
QKPEL
506
VDIVI
511
EEFST
516
LIVQR
521
PGAQA
526
IKFET
531
KIDSF
536
HITGL
541
PDNSE
546
KPRLL
551
SSLDD
556
AMSLF
561
QITFE
566
INPLD
571
ETVSQ
576
RCIIE
581
AEPLE
586
IIYDA
591
RTVNS
596
IVEFF
601
RPPKE
606
VHLAQ
611
LTAAT
616
LTKLE
621
EFRSK
626
TATGL
631
LYIIE
636
TQKVL
641
DLKIN
646
LKASY
651
IIVPQ
656
DGIFS
661
PTSNL
666
LLLDL
671
GHLKV
676
TSKSR
681
SELPD
686
VKQGE
691
ANLKE
696
IMDRA
701
YDSFD
706
IQLTS
711
VQLLY
716
SRVGD
721
NWREA
726
RKLSV
731
STQHI
736
LVPMH
741
FNLEL
746
SKAMV
751
FMDVR
756
MPKFK
761
IYGKL
766
PLISL
771
RISDK
776
KLQGI
781
MELIE
786
SIPKP
791
EPVTE
796
VSAPV
801
KSFQI
806
QTSTS
811
LGTSQ
816
ISQKI
821
IPLLE
826
LPSVS
831
EDDSE
836
EEFFD
841
APCSP
846
LEEPL
851
QFPTG
856
VKSIR
861
TRKLQ
866
KQDCS
871
VNMTT
876
FKIRF
881
EVPKV
886
LIEFY
891
HLVGD
896
CELSV
901
VEILV
906
LGLGA
911
EIEIR
916
TYDLK
921
ANAFL
926
KEFCL
931
KCPEY
936
LDENK
941
KPVYL
946
VTTLD
951
NTMED
956
LLTLE
961
YVKAE
966
KNVPD
971
LKSTY
976
NNVLQ
981
LIKVN
986
FSSLD
991
IHLHT
996
EALLN
1001
TINYL
1006
HNILP
1011
QSEEK
1016
SAPVS
1021
TTETE
1026
DKGDV
1031
IKKLG
1036
LDSEM
1041
IMRPS
1046
ETEIN
1051
AKLRN
1056
IIVLD
1061
SDITA
1066
IYKKA
1071
VYITG
1076
KEVFS
1081
FKMVS
1086
YMDAT
1091
AGSAY
1096
TDMNV
1101
VDIQV
1106
NLIVG
1111
CIEVV
1116
FVTKF
1121
LYSIL
1126
AFIDN
1131
FQAAK
1136
QALAE
1141
ATVQA
1146
AGMAA
1151
TGVKE
1156
LAQRS
1161
SRMAL
1166
DINIK
1171
APVVV
1176
IPQSP
1181
VSENV
1186
FVADF
1191
GLITM
1196
TNTFH
1201
MITES
1206
QSSPP
1211
PVIDL
1216
ITIKL
1221
SEMRL
1226
YRSRF
1231
INDAY
1236
QEVLD
1241
LLLPL
1246
NLEVV
1251
VERNL
1256
CWEWY
1261
QEVPC
1266
FNVNA
1271
QLKPM
1276
EFILS
1281
QEDIT
1286
TIFKT
1291
LHGNI
1296
WYEKD
1301
GSASP
1306
AVTKD
1311
QYSAT
1316
SGVTT
1321
NASHH
1326
SGGAT
1331
VVTAA
1336
VVEVH
1341
SRALL
1346
VKTTL
1351
NISFK
1356
TDDLT
1361
MVLYS
1366
PGPKQ
1371
ASFTD
1376
VRDPS
1381
LKLAE
1386
FKLEN
1391
IISTL
1396
KMYTD
1401
GSTFS
1406
SFSLK
1411
NCILD
1416
DKRPH
1421
VKKAT
1426
PRMIG
1431
LTVGF
1436
DKKDM
1441
MDIKY
1446
RKVRD
1451
GCVTD
1456
AVFQE
1461
MYICA
1466
SVEFL
1471
QTVAN
1476
VFLEA
1481
YTTGT
1486
AVETS
1491
VQTWT
1496
AKEEV
1501
PTQES
1506
VKWEI
1511
NVIIK
1516
NPEIV
1521
FVADM
1526
TKNDA
1531
PALVI
1536
TTQCE
1541
ICYKG
1546
NLENS
1551
TMTAA
1556
IKDLQ
1561
VRACP
1566
FLPVK
1571
RKGKI
1576
TTVLQ
1581
PCDLF
1586
YQTTQ
1591
KGTDP
1596
QVIDM
1601
SVKSL
1606
TLKVS
1611
PVIIN
1616
TMITI
1621
TSALY
1626
TTKET
1631
IPEET
1636
ASSTA
1641
HLWEK
1646
KDTKT
1651
LKMWF
1656
LEESN
1661
ETEKI
1666
APTTE
1671
LVPKG
1676
EMIKM
1681
NIDSI
1686
FIVLE
1691
AGIGH
1696
RTVPM
1701
LLAKS
1706
RFSGE
1711
GKNWS
1716
SLINL
1721
HCQLE
1726
LEVHY
1731
YNEMF
1736
GVWEP
1741
LLEPL
1746
EIDQT
1751
EDFRP
1756
WNLGI
1761
KMKKK
1766
AKMAI
1771
VESDP
1776
EEENY
1781
KVPEY
1786
KTVIS
1791
FHSKD
1796
QLNIT
1801
LSKCG
1806
LVMLN
1811
NLVKA
1816
FTEAA
1821
TGSSA
1826
DFVKD
1831
LAPFM
1836
ILNSL
1841
GLTIS
1846
VSPSD
1851
SFSVL
1856
NIPMA
1861
KSYVL
1866
KNGES
1871
LSMDY
1876
IRTKD
1881
NDHFN
1886
AMTSL
1891
SSKLF
1896
FILLT
1901
PVNHS
1906
TADKI
1911
PLTKV
1916
GRRLY
1921
TVRHR
1926
ESGVE
1931
RSIVC
1936
QIDTV
1941
EGSKK
1946
VTIRS
1951
PVQIR
1956
NHFSV
1961
PLSVY
1966
EGDTL
1971
LGTAS
1976
PENEF
1981
NIPLG
1986
SYRSF
1991
IFLKP
1996
EDENY
2001
QMCEG
2006
IDFEE
2011
IIKND
2016
GALLK
2021
KKCRS
2026
KNPSK
2031
ESFLI
2036
NIVPE
2041
KDNLT
2046
SLSVY
2051
SEDGW
2056
DLPYI
2061
MHLWP
2066
PILLR
2071
NLLPY
2076
KIAYY
2081
IEGIE
2086
NSVFT
2091
LSEGH
2096
SAQIC
2101
TAQLG
2106
KARLH
2111
LKLLD
2116
YLNHD
2121
WKSEY
2126
HIKPN
2131
QQDIS
2136
FVSFT
2141
CVTEM
2146
EKTDL
2151
DIAVH
2156
MTYNT
2161
GQTVV
2166
AFHSP
2171
YWMVN
2176
KTGRM
2181
LQYKA
2186
DGIHR
2191
KHPPN
2196
YKKPV
2201
LFSFQ
2206
PNHFF
2211
NNNKV
2216
QLMVT
2221
DSELS
2226
NQFSI
2231
DTVGS
2236
HGAVK
2241
CKGLK
2246
MDYQV
2251
GVTID
2256
LSSFN
2261
ITRIV
2266
TFTPF
2271
YMIKN
2276
KSKYH
2281
ISVAE
2286
EGNDK
2291
WLSLD
2296
LEQCI
2301
PFWPE
2306
YASSK
2311
LLIQV
2316
ERSED
2321
PPKRI
2326
YFNKQ
2331
ENCIL
2336
LRLDN
2341
ELGGI
2346
IAEVN
2351
LAEHS
2356
TVITF
2361
LDYHD
2366
GAATF
2371
LLINH
2376
TKNEL
2381
VQYNQ
2386
SSLSE
2391
IEDSL
2396
PPGKA
2401
VFYTW
2406
ADPVG
2411
SRRLK
2416
WRCRK
2421
SHGEV
2426
TQKDD
2431
MMMPI
2436
DLGEK
2441
TIYLV
2446
SFFEG
2451
LQRII
2456
LFTED
2461
PRVFK
2466
VTYES
2471
EKAEL
2476
AEQEI
2481
AVALQ
2486
DVGIS
2491
LVNNY
2496
TKQEV
2501
AYIGI
2506
TSSDV
2511
VWETK
2516
PKKKA
2521
RWKPM
2526
SVKHT
2531
EKLER
2536
EFKEY
2541
TESSP
2546
SEDKV
2551
IQLDT
2556
NVPVR
2561
LTPTG
2566
HNMKI
2571
LQPHV
2576
IALRR
2581
NYLPA
2586
LKVEY
2591
NTSAH
2596
QSSFR
2601
IQIYR
2606
IQIQN
2611
QIHGA
2616
VFPFV
2621
FYPVK
2626
PPKSV
2631
TMDSA
2636
PKPFT
2641
DVSIV
2646
MRSAG
2651
HSQIS
2656
RIKYF
2661
KVLIQ
2666
EMDLR
2671
LDLGF
2676
IYALT
2681
DLMTE
2686
AEVTE
2691
NTEVE
2696
LFHKD
2701
IEAFK
2706
EEYKT
2711
ASLVD
2716
QSQVS
2721
LYEYF
2726
HISPI
2731
KLHLS
2736
VSLSS
2741
GREEA
2746
KDSKQ
2751
NGGLI
2756
PVHSL
2761
NLLLK
2766
SIGAT
2771
LTDVQ
2776
DVVFK
2781
LAFFE
2786
LNYQF
2791
HTTSD
2796
LQSEV
2801
IRHYS
2806
KQAIK
2811
QMYVL
2816
ILGLD
2821
VLGNP
2826
FGLIR
2831
EFSEG
2836
VEAFF
2841
YEPYQ
2846
GAIQG
2851
PEEFV
2856
EGMAL
2861
GLKAL
2866
VGGAV
2871
GGLAG
2876
AASKI
2881
TGAMA
2886
KGVAA
2891
MTMDE
2896
DYQQK
2901
RREAM
2906
NKQPA
2911
GFREG
2916
ITRGG
2921
KGLVS
2926
GFVSG
2931
ITGIV
2936
TKPIK
2941
GAQKG
2946
GAAGF
2951
FKGVG
2956
KGLVG
2961
AVARP
2966
TGGII
2971
DMASS
2976
TFQGI
2981
KRATE
2986
TSEVE
2991
SLRPP
2996
RFFNE
3001
DGVIR
3006
PYRLR
3011
DGTGN
3016
QMLQV
3021
MENGR
3026
FAKYK
3031
YFTHV
3036
MINKT
3041
DMLMI
3046
TRRGV
3051
LFVTK
3056
GTFGQ
3061
LTCEW
3066
QYSFD
3071
EFTKE
3076
PFIVH
3081
GRRLR
3086
IEAKE
3091
RVKSV
3096
FHARE
3101
FGKII
3106
NFKTP
3111
EDARW
3116
ILTKL
3121
QEARE
3126
PSPSL
3131
Mutation Information
DNA mutation:
None
Peptide Range:
2401 ~ 2425
Mut AA position:
2413 (13 in Wild Type peptide)
Alignment
Wild Type:
"PPGKAVFYTWADPVGSRRLKWRCRK
||||||||||||.||||||||||||
Mutant:
PPGKAVFYTWADSVGSRRLKWRCRK"
Clin Cancer Res, 2017
Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 ExpressionGene Name (from Reference) VPS13A
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
ELISPOT assay