Immunogenicity 11221
Sample ID
3716
Response
Negative
Tumor Type
Melanoma
Gene Symbol
TNKS1BP1
Transcript ID
None
HLA INFO
B*15:01
TCR INFO
No TCR info found!
Full length protein sequence (1729 aa)
MKVST
1
LRESS
6
AMASP
11
LPREM
16
EEELV
21
PTGSE
26
PGDTR
31
AKPPV
36
KPKPR
41
ALPAK
46
PALPA
51
KPSLL
56
VPVGP
61
RPPRG
66
PLAEL
71
PSARK
76
MNMLA
81
GPQPY
86
GGSKR
91
PLPFA
96
PRPAV
101
EASTG
106
GEATQ
111
ETGKE
116
EAGKE
121
EPPPL
126
TPPAR
131
CAAPG
136
GVRKA
141
PAPFR
146
PASER
151
FAATT
156
VEEIL
161
AKMEQ
166
PRKEV
171
LASPD
176
RLWGS
181
RLTFN
186
HDGSS
191
RYGPR
196
TYGTT
201
TAPRD
206
EDGST
211
LFRGW
216
SQEGP
221
VKSPA
226
ECREE
231
HSKTP
236
EERSL
241
PSDLA
246
FNGDL
251
AKAAS
256
SELPA
261
DISKP
266
WIPSS
271
PAPSS
276
ENGGP
281
ASPGL
286
PAEAS
291
GSGPG
296
SPHLH
301
PPDKS
306
SPCHS
311
QLLEA
316
QTPEA
321
SQASP
326
CPAVT
331
PSAPS
336
AALPD
341
EGSRH
346
TPSPG
351
LPAEG
356
APEAP
361
RPSSP
366
PPEVL
371
EPHSL
376
DQPPA
381
TSPRP
386
LIEVG
391
ELLDL
396
TRTFP
401
SGGEE
406
EAKGD
411
AHLRP
416
TSLVQ
421
RRFSE
426
GVLQS
431
PSQDQ
436
EKLGG
441
SLAAL
446
PQGQG
451
SQLAL
456
DRPFG
461
AESNW
466
SLSQS
471
FEWTF
476
PTRPS
481
GLGVW
486
RLDSP
491
PPSPI
496
TEASE
501
AAEAA
506
EAGNL
511
AVSSR
516
EEGVS
521
QQGQG
526
AGSAP
531
SGSGS
536
SWVQG
541
DDPSM
546
SLTQK
551
GDGES
556
QPQFP
561
AVPLE
566
PLPTT
571
EGTPG
576
LPLQQ
581
AEERY
586
ESQEP
591
LAGQE
596
SPLPL
601
ATREA
606
ALPIL
611
EPVLG
616
QEQPA
621
APDQP
626
CVLFA
631
DAPEP
636
GQALP
641
VEEEA
646
VTLAR
651
AETTQ
656
ARTEA
661
QDLCR
666
ASPEP
671
PGPES
676
SSRWL
681
DDLLA
686
SPPPS
691
GGGAR
696
RGAGA
701
ELKDT
706
QSPST
711
CSEGL
716
LGWSQ
721
KDLQS
726
EFGIT
731
GDPQP
736
SSFSP
741
SSWCQ
746
GASQD
751
YGLGG
756
ASPRG
761
DPGLG
766
ERDWT
771
SKYGQ
776
GAGEG
781
STREW
786
ASRCG
791
IGQEE
796
MEASS
801
SQDQS
806
KVSAP
811
GVLTA
816
QDRVV
821
GKPAQ
826
LGTQR
831
SQEAD
836
VQDWE
841
FRKRD
846
SQGTY
851
SSRDA
856
ELQDQ
861
EFGKR
866
DSLGT
871
YSSRD
876
VSLGD
881
WEFGK
886
RDSLG
891
AYASQ
896
DANEQ
901
GQDLG
906
KRDHH
911
GRYSS
916
QDADE
921
QDWEF
926
QKRDV
931
SLGTY
936
GSRAA
941
EPQEQ
946
EFGKS
951
AWIRD
956
YSSGG
961
SSRTL
966
DAQDR
971
SFGTR
976
PLSSG
981
FSPEE
986
AQQQD
991
EEFEK
996
KIPSV
1001
EDSLG
1006
EGSRD
1011
AGRPG
1016
ERGSG
1021
GLFSP
1026
STAHV
1031
PDGAL
1036
GQRDQ
1041
SSWQN
1046
SDASQ
1051
EVGGH
1056
QERQQ
1061
AGAQG
1066
PGSAD
1071
LEDGE
1076
MGKRG
1081
WVGEF
1086
SLSVG
1091
PQREA
1096
AFSPG
1101
QQDWS
1106
RDFCI
1111
EASER
1116
SYQFG
1121
IIGND
1126
RVSGA
1131
GFSPS
1136
SKMEG
1141
GHFVP
1146
PGKTT
1151
AGSVD
1156
WTDQL
1161
GLRNL
1166
EVSSC
1171
VGSGG
1176
SSEAR
1181
ESAVG
1186
QMGWS
1191
GGLSL
1196
RDMNL
1201
TGCLE
1206
SGGSE
1211
EPGGI
1216
GVGEK
1221
DWTSD
1226
VNVKS
1231
KDLAE
1236
VGEGG
1241
GHSQA
1246
RESGV
1251
GQTDW
1256
SGVEA
1261
GEFLK
1266
SRERG
1271
VGQAD
1276
WTPDL
1281
GLRNM
1286
APGAV
1291
CSPGE
1296
SKELG
1301
VGQMD
1306
WGNNL
1311
GLRDL
1316
EVTCD
1321
PDSGG
1326
SQGLR
1331
GCGVG
1336
QMDWT
1341
QDLAP
1346
QNVEL
1351
FGAPS
1356
EAREH
1361
GVGGV
1366
SQCPE
1371
PGLRH
1376
NGSLS
1381
PGLEA
1386
RDPLE
1391
ARELG
1396
VGETS
1401
GPETQ
1406
GEDYS
1411
SSSLE
1416
PHPAD
1421
PGMET
1426
GEALS
1431
FGASP
1436
GRCPA
1441
RPPPS
1446
GSQGL
1451
LEEML
1456
AASSS
1461
KAVAR
1466
RESAA
1471
SGLGG
1476
LLEEE
1481
GAGAG
1486
AAQEE
1491
VLEPG
1496
RDSPP
1501
SWRPQ
1506
PDGEA
1511
SQTED
1516
VDGTW
1521
GSSAA
1526
RWSDQ
1531
GPAQT
1536
SRRPS
1541
QGPPA
1546
RSPSQ
1551
DFSFI
1556
EDTEI
1561
LDSAM
1566
YRSRA
1571
NLGRK
1576
RGHRA
1581
PVIRP
1586
GGTLG
1591
LSEAA
1596
DSDAH
1601
LFQDS
1606
TEPRA
1611
SRVPS
1616
SDEEV
1621
VEEPQ
1626
SRRTR
1631
MSLGT
1636
KGLKV
1641
NLFPG
1646
LSPSA
1651
LKAKL
1656
RPRNR
1661
SAEEG
1666
ELAES
1671
KSSQK
1676
ESAVQ
1681
RSKSC
1686
KVPGL
1691
GKPLT
1696
LPPKP
1701
EKSSG
1706
SEGSS
1711
PNWLQ
1716
ALKLK
1721
KKKV
1726
Mutation Information
DNA mutation:
None
Peptide Range:
510 ~ 534
Mut AA position:
522 (13 in Wild Type peptide)
Alignment
Wild Type:
"AEAGNLAVSSREEGVSQQGQGAGSA
||||||||||||.||||||||||||
Mutant:
AEAGNLAVSSREKGVSQQGQGAGSA"
Clin Cancer Res, 2017
Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 ExpressionGene Name (from Reference) TNKS1BP1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
ELISPOT assay