Immunogenicity 11224
Sample ID
3716
Response
Negative
Tumor Type
Melanoma
Gene Symbol
VPS13A
Transcript ID
None
HLA INFO
B*15:01
TCR INFO
No TCR info found!
Full length protein sequence (3174 aa)
MVFES
1
VVVDV
6
LNRFL
11
GDYVV
16
DLDTS
21
QLSLG
26
IWKGA
31
VALKN
36
LQIKE
41
NALSQ
46
LDVPF
51
KVKVG
56
HIGNL
61
KLIIP
66
WKNLY
71
TQPVE
76
AVLEE
81
IYLLI
86
VPSSR
91
IKYDP
96
LKEEK
101
QLMEA
106
KQQEL
111
KRIEE
116
AKQKV
121
VDQEQ
126
HLPEK
131
QDTFA
136
EKLVT
141
QIIKN
146
LQVKI
151
SSIHI
156
RYEDD
161
ITNRD
166
KPLSF
171
GISLQ
176
NLSMQ
181
TTDQY
186
WVPCL
191
HDETE
196
KLVRK
201
LIRLD
206
NLFAY
211
WNVKS
216
QMFYL
221
SDYDN
226
SLDDL
231
KNGIV
236
NENIV
241
PEGYD
246
FVFRP
251
ISANA
256
KLVMN
261
RRSDF
266
DFSAP
271
KINLE
276
IELHN
281
IAIEF
286
NKPQY
291
FSIME
296
LLESV
301
DMMAQ
306
NLPYR
311
KFKPD
316
VPLHH
321
HAREW
326
WAYAI
331
HGVLE
336
VNVCP
341
RLWMW
346
SWKHI
351
RKHRQ
356
KVKQY
361
KELYK
366
KKLTS
371
KKPPG
376
ELLVS
381
LEELE
386
KTLDV
391
FNITI
396
ARQTA
401
EVEVK
406
KAGYK
411
IYKEG
416
VKDPE
421
DNKGW
426
FSWLW
431
SWSEQ
436
NTNEQ
441
QPDVQ
446
PETLE
451
EMLTP
456
EEKAL
461
LYEAI
466
GYSET
471
AVDPT
476
LLKTF
481
EALKF
486
FVHLK
491
SMSIV
496
LRENH
501
QKPEL
506
VDIVI
511
EEFST
516
LIVQR
521
PGAQA
526
IKFET
531
KIDSF
536
HITGL
541
PDNSE
546
KPRLL
551
SSLDD
556
AMSLF
561
QITFE
566
INPLD
571
ETVSQ
576
RCIIE
581
AEPLE
586
IIYDA
591
RTVNS
596
IVEFF
601
RPPKE
606
VHLAQ
611
LTAAT
616
LTKLE
621
EFRSK
626
TATGL
631
LYIIE
636
TQKVL
641
DLKIN
646
LKASY
651
IIVPQ
656
DGIFS
661
PTSNL
666
LLLDL
671
GHLKV
676
TSKSR
681
SELPD
686
VKQGE
691
ANLKE
696
IMDRA
701
YDSFD
706
IQLTS
711
VQLLY
716
SRVGD
721
NWREA
726
RKLSV
731
STQHI
736
LVPMH
741
FNLEL
746
SKAMV
751
FMDVR
756
MPKFK
761
IYGKL
766
PLISL
771
RISDK
776
KLQGI
781
MELIE
786
SIPKP
791
EPVTE
796
VSAPV
801
KSFQI
806
QTSTS
811
LGTSQ
816
ISQKI
821
IPLLE
826
LPSVS
831
EDDSE
836
EEFFD
841
APCSP
846
LEEPL
851
QFPTG
856
VKSIR
861
TRKLQ
866
KQDCS
871
VNMTT
876
FKIRF
881
EVPKV
886
LIEFY
891
HLVGD
896
CELSV
901
VEILV
906
LGLGA
911
EIEIR
916
TYDLK
921
ANAFL
926
KEFCL
931
KCPEY
936
LDENK
941
KPVYL
946
VTTLD
951
NTMED
956
LLTLE
961
YVKAE
966
KNVPD
971
LKSTY
976
NNVLQ
981
LIKVN
986
FSSLD
991
IHLHT
996
EALLN
1001
TINYL
1006
HNILP
1011
QSEEK
1016
SAPVS
1021
TTETE
1026
DKGDV
1031
IKKLA
1036
LKLST
1041
NEDII
1046
TLQIL
1051
AELSC
1056
LQIFI
1061
QDQKC
1066
NISEI
1071
KIEGL
1076
DSEMI
1081
MRPSE
1086
TEINA
1091
KLRNI
1096
IVLDS
1101
DITAI
1106
YKKAV
1111
YITGK
1116
EVFSF
1121
KMVSY
1126
MDATA
1131
GSAYT
1136
DMNVV
1141
DIQVN
1146
LIVGC
1151
IEVVF
1156
VTKFL
1161
YSILA
1166
FIDNF
1171
QAAKQ
1176
ALAEA
1181
TVQAA
1186
GMAAT
1191
GVKEL
1196
AQRSS
1201
RMALD
1206
INIKA
1211
PVVVI
1216
PQSPV
1221
SENVF
1226
VADFG
1231
LITMT
1236
NTFHM
1241
ITESQ
1246
SSPPP
1251
VIDLI
1256
TIKLS
1261
EMRLY
1266
RSRFI
1271
NDAYQ
1276
EVLDL
1281
LLPLN
1286
LEVVV
1291
ERNLC
1296
WEWYQ
1301
EVPCF
1306
NVNAQ
1311
LKPME
1316
FILSQ
1321
EDITT
1326
IFKTL
1331
HGNIW
1336
YEKDG
1341
SASPA
1346
VTKDQ
1351
YSATS
1356
GVTTN
1361
ASHHS
1366
GGATV
1371
VTAAV
1376
VEVHS
1381
RALLV
1386
KTTLN
1391
ISFKT
1396
DDLTM
1401
VLYSP
1406
GPKQA
1411
SFTDV
1416
RDPSL
1421
KLAEF
1426
KLENI
1431
ISTLK
1436
MYTDG
1441
STFSS
1446
FSLKN
1451
CILDD
1456
KRPHV
1461
KKATP
1466
RMIGL
1471
TVGFD
1476
KKDMM
1481
DIKYR
1486
KVRDG
1491
CVTDA
1496
VFQEM
1501
YICAS
1506
VEFLQ
1511
TVANV
1516
FLEAY
1521
TTGTA
1526
VETSV
1531
QTWTA
1536
KEEVP
1541
TQESV
1546
KWEIN
1551
VIIKN
1556
PEIVF
1561
VADMT
1566
KNDAP
1571
ALVIT
1576
TQCEI
1581
CYKGN
1586
LENST
1591
MTAAI
1596
KDLQV
1601
RACPF
1606
LPVKR
1611
KGKIT
1616
TVLQP
1621
CDLFY
1626
QTTQK
1631
GTDPQ
1636
VIDMS
1641
VKSLT
1646
LKVSP
1651
VIINT
1656
MITIT
1661
SALYT
1666
TKETI
1671
PEETA
1676
SSTAH
1681
LWEKK
1686
DTKTL
1691
KMWFL
1696
EESNE
1701
TEKIA
1706
PTTEL
1711
VPKGE
1716
MIKMN
1721
IDSIF
1726
IVLEA
1731
GIGHR
1736
TVPML
1741
LAKSR
1746
FSGEG
1751
KNWSS
1756
LINLH
1761
CQLEL
1766
EVHYY
1771
NEMFG
1776
VWEPL
1781
LEPLE
1786
IDQTE
1791
DFRPW
1796
NLGIK
1801
MKKKA
1806
KMAIV
1811
ESDPE
1816
EENYK
1821
VPEYK
1826
TVISF
1831
HSKDQ
1836
LNITL
1841
SKCGL
1846
VMLNN
1851
LVKAF
1856
TEAAT
1861
GSSAD
1866
FVKDL
1871
APFMI
1876
LNSLG
1881
LTISV
1886
SPSDS
1891
FSVLN
1896
IPMAK
1901
SYVLK
1906
NGESL
1911
SMDYI
1916
RTKDN
1921
DHFNA
1926
MTSLS
1931
SKLFF
1936
ILLTP
1941
VNHST
1946
ADKIP
1951
LTKVG
1956
RRLYT
1961
VRHRE
1966
SGVER
1971
SIVCQ
1976
IDTVE
1981
GSKKV
1986
TIRSP
1991
VQIRN
1996
HFSVP
2001
LSVYE
2006
GDTLL
2011
GTASP
2016
ENEFN
2021
IPLGS
2026
YRSFI
2031
FLKPE
2036
DENYQ
2041
MCEGI
2046
DFEEI
2051
IKNDG
2056
ALLKK
2061
KCRSK
2066
NPSKE
2071
SFLIN
2076
IVPEK
2081
DNLTS
2086
LSVYS
2091
EDGWD
2096
LPYIM
2101
HLWPP
2106
ILLRN
2111
LLPYK
2116
IAYYI
2121
EGIEN
2126
SVFTL
2131
SEGHS
2136
AQICT
2141
AQLGK
2146
ARLHL
2151
KLLDY
2156
LNHDW
2161
KSEYH
2166
IKPNQ
2171
QDISF
2176
VSFTC
2181
VTEME
2186
KTDLD
2191
IAVHM
2196
TYNTG
2201
QTVVA
2206
FHSPY
2211
WMVNK
2216
TGRML
2221
QYKAD
2226
GIHRK
2231
HPPNY
2236
KKPVL
2241
FSFQP
2246
NHFFN
2251
NNKVQ
2256
LMVTD
2261
SELSN
2266
QFSID
2271
TVGSH
2276
GAVKC
2281
KGLKM
2286
DYQVG
2291
VTIDL
2296
SSFNI
2301
TRIVT
2306
FTPFY
2311
MIKNK
2316
SKYHI
2321
SVAEE
2326
GNDKW
2331
LSLDL
2336
EQCIP
2341
FWPEY
2346
ASSKL
2351
LIQVE
2356
RSEDP
2361
PKRIY
2366
FNKQE
2371
NCILL
2376
RLDNE
2381
LGGII
2386
AEVNL
2391
AEHST
2396
VITFL
2401
DYHDG
2406
AATFL
2411
LINHT
2416
KNELV
2421
QYNQS
2426
SLSEI
2431
EDSLP
2436
PGKAV
2441
FYTWA
2446
DPVGS
2451
RRLKW
2456
RCRKS
2461
HGEVT
2466
QKDDM
2471
MMPID
2476
LGEKT
2481
IYLVS
2486
FFEGL
2491
QRIIL
2496
FTEDP
2501
RVFKV
2506
TYESE
2511
KAELA
2516
EQEIA
2521
VALQD
2526
VGISL
2531
VNNYT
2536
KQEVA
2541
YIGIT
2546
SSDVV
2551
WETKP
2556
KKKAR
2561
WKPMS
2566
VKHTE
2571
KLERE
2576
FKEYT
2581
ESSPS
2586
EDKVI
2591
QLDTN
2596
VPVRL
2601
TPTGH
2606
NMKIL
2611
QPHVI
2616
ALRRN
2621
YLPAL
2626
KVEYN
2631
TSAHQ
2636
SSFRI
2641
QIYRI
2646
QIQNQ
2651
IHGAV
2656
FPFVF
2661
YPVKP
2666
PKSVT
2671
MDSAP
2676
KPFTD
2681
VSIVM
2686
RSAGH
2691
SQISR
2696
IKYFK
2701
VLIQE
2706
MDLRL
2711
DLGFI
2716
YALTD
2721
LMTEA
2726
EVTEN
2731
TEVEL
2736
FHKDI
2741
EAFKE
2746
EYKTA
2751
SLVDQ
2756
SQVSL
2761
YEYFH
2766
ISPIK
2771
LHLSV
2776
SLSSG
2781
REEAK
2786
DSKQN
2791
GGLIP
2796
VHSLN
2801
LLLKS
2806
IGATL
2811
TDVQD
2816
VVFKL
2821
AFFEL
2826
NYQFH
2831
TTSDL
2836
QSEVI
2841
RHYSK
2846
QAIKQ
2851
MYVLI
2856
LGLDV
2861
LGNPF
2866
GLIRE
2871
FSEGV
2876
EAFFY
2881
EPYQG
2886
AIQGP
2891
EEFVE
2896
GMALG
2901
LKALV
2906
GGAVG
2911
GLAGA
2916
ASKIT
2921
GAMAK
2926
GVAAM
2931
TMDED
2936
YQQKR
2941
REAMN
2946
KQPAG
2951
FREGI
2956
TRGGK
2961
GLVSG
2966
FVSGI
2971
TGIVT
2976
KPIKG
2981
AQKGG
2986
AAGFF
2991
KGVGK
2996
GLVGA
3001
VARPT
3006
GGIID
3011
MASST
3016
FQGIK
3021
RATET
3026
SEVES
3031
LRPPR
3036
FFNED
3041
GVIRP
3046
YRLRD
3051
GTGNQ
3056
MLQVM
3061
ENGRF
3066
AKYKY
3071
FTHVM
3076
INKTD
3081
MLMIT
3086
RRGVL
3091
FVTKG
3096
TFGQL
3101
TCEWQ
3106
YSFDE
3111
FTKEP
3116
FIVHG
3121
RRLRI
3126
EAKER
3131
VKSVF
3136
HAREF
3141
GKIIN
3146
FKTPE
3151
DARWI
3156
LTKLQ
3161
EAREP
3166
SPSL
3171
Mutation Information
DNA mutation:
None
Peptide Range:
58 ~ 82
Mut AA position:
70 (13 in Wild Type peptide)
Alignment
Wild Type:
"KVGHIGNLKLIIPWKNLYTQPVEAV
||||||||||||.||||||||||||
Mutant:
KVGHIGNLKLIISWKNLYTQPVEAV"
Clin Cancer Res, 2017
Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 ExpressionGene Name (from Reference) VPS13A
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
ELISPOT assay