Immunogenicity 11225
Sample ID
3716
Response
Negative
Tumor Type
Melanoma
Gene Symbol
VPS39
Transcript ID
None
HLA INFO
B*15:01
TCR INFO
No TCR info found!
Full length protein sequence (907 aa)
MHDAF
1
EPVPI
6
LEKLP
11
LQIDC
16
LAAWE
21
EWLLV
26
GTKQG
31
HLLLY
36
RIRKD
41
VVPAD
46
VASPE
51
SGSCN
56
RFEVT
61
LEKSN
66
KNFSK
71
KIQQI
76
HVVSQ
81
FKILV
86
SLLEN
91
NIYVH
96
DLLTF
101
QQITT
106
VSKAK
111
GASLF
116
TCDLQ
121
HTETG
126
EEVLR
131
MCVAV
136
KKKLQ
141
LYFWK
146
DREFH
151
ELQGD
156
FSVPD
161
VPKSM
166
AWCEN
171
SICVG
176
FKRDY
181
YLIRV
186
DGKGS
191
IKELF
196
PTGKQ
201
LEPLV
206
APLAD
211
GKVAV
216
GQDDL
221
TVVLN
226
EEGIC
231
TQKCA
236
LNWTD
241
IPVAM
246
EHQPP
251
YIIAV
256
LPRYV
261
EIRTF
266
EPRLL
271
VQSIE
276
LQRPR
281
FITSG
286
GSNII
291
YVASN
296
HFVWR
301
LIPVP
306
MATQI
311
QQLLQ
316
DKQFE
321
LALQL
326
AEMKD
331
DSDSE
336
KQQQI
341
HHIKN
346
LYAFN
351
LFCQK
356
RFDES
361
MQVFA
366
KLGTD
371
PTHVM
376
GLYPD
381
LLPTD
386
YRKQL
391
QYPNP
396
LPVLS
401
GAELE
406
KAHLA
411
LIDYL
416
TQKRS
421
QLVKK
426
LNDSD
431
HQSST
436
SPLME
441
GTPTI
446
KSKKK
451
LLQII
456
DTTLL
461
KCYLH
466
TNVAL
471
VAPLL
476
RLENN
481
HCHIE
486
ESEHV
491
LKKAH
496
KYSEL
501
IILYE
506
KKGLH
511
EKALQ
516
VLVDQ
521
SKKAN
526
SPLKG
531
HERTV
536
QYLQH
541
LGTEN
546
LHLIF
551
SYSVW
556
VLRDF
561
PEDGL
566
KIFTE
571
DLPEV
576
ESLPR
581
DRVLG
586
FLIEN
591
FKGLA
596
IPYLE
601
HIIHV
606
WEETG
611
SRFHN
616
CLIQL
621
YCEKV
626
QGLMK
631
EYLLS
636
FPAGK
641
TPVPA
646
GEEEG
651
ELGEY
656
RQKLL
661
MFLEI
666
SSYYD
671
PGRLI
676
CDFPF
681
DGLLE
686
ERALL
691
LGRMG
696
KHEQA
701
LFIYV
706
HILKD
711
TRMAE
716
EYCHK
721
HYDRN
726
KDGNK
731
DVYLS
736
LLRMY
741
LSPPS
746
IHCLG
751
PIKLE
756
LLEPK
761
ANLQA
766
ALQVL
771
ELHHS
776
KLDTT
781
KALNL
786
LPANT
791
QINDI
796
RIFLE
801
KVLEE
806
NAQKK
811
RFNQV
816
LKNLL
821
HAEFL
826
RVQEE
831
RILHQ
836
QVKCI
841
ITEEK
846
VCMVC
851
KKKIG
856
NRRCR
861
CQRSG
866
HLEAV
871
LTPKP
876
FSSLQ
881
CICKI
886
PQWSG
891
RPLLL
896
FQRGK
901
PS
906
Mutation Information
DNA mutation:
None
Peptide Range:
630 ~ 654
Mut AA position:
642 (13 in Wild Type peptide)
Alignment
Wild Type:
"VQGLMKEYLLSFPAGKTPVPAGEEE
||||||||||||.||||||||||||
Mutant:
VQGLMKEYLLSFSAGKTPVPAGEEE"
Clin Cancer Res, 2017
Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 ExpressionGene Name (from Reference) VPS39
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
ELISPOT assay