Immunogenicity 11229
Sample ID
3716
Response
Negative
Tumor Type
Melanoma
Gene Symbol
ZC3H18
Transcript ID
None
HLA INFO
B*15:01
TCR INFO
No TCR info found!
Full length protein sequence (848 aa)
MDVAE
1
SPERD
6
PHSPE
11
DEEQP
16
QGLSD
21
DDILR
26
DSGSD
31
QDLDG
36
AGVRA
41
SDLED
46
EESAA
51
RGPSQ
56
EEEDN
61
HSDEE
66
DRASE
71
PKSQD
76
QDSEV
81
NELSR
86
GPTSS
91
PCEEE
96
GDEGE
101
EDRTS
106
DLRDE
111
ASSVT
116
RELDE
121
HELDY
126
DEEVP
131
EEPAP
136
AVQED
141
EAEKA
146
GAEDD
151
EEKGE
156
GTPRE
161
EGKAG
166
VQSVG
171
EKESL
176
EAAKE
181
KKKED
186
DDGEI
191
DDGEI
196
DDDDL
201
EEGEV
206
KDPSD
211
RKVRP
216
RPTCR
221
FFMKD
226
VVTPL
231
STLLP
236
PISNS
241
IPFRG
246
QVKGN
251
CTWGM
256
NCRFI
261
HPGVN
266
DKGNY
271
SLITK
276
ADPFP
281
PNGAP
286
PLGPH
291
PLMPA
296
NPWGG
301
PVVDE
306
ILPPP
311
PPEPP
316
TESAW
321
ERGLR
326
HAKEV
331
LKKAT
336
IRKEQ
341
EPDFE
346
EKRFT
351
VTIGE
356
DEREF
361
DKENE
366
VFRDW
371
NSRIP
376
RDVRD
381
TVRQA
386
EPPKK
391
EAATT
396
GPQVK
401
RADEW
406
KDPWR
411
RSKSP
416
KKKLG
421
VSVSP
426
SRARR
431
RRKTS
436
ASSAS
441
ASNSS
446
RSSSR
451
SSSYS
456
GSGSS
461
RSRSR
466
SSSYS
471
SYSSR
476
SSRHS
481
SFSGS
486
RSRSR
491
SFSSS
496
PSPSP
501
TPSPH
506
RPSIR
511
TKGEP
516
APPPG
521
KAGEK
526
SVKKP
531
APPPA
536
PPQAT
541
KTTAP
546
VPEPT
551
KPGDP
556
REARR
561
KERPA
566
RTPPR
571
RRTLS
576
GSGSG
581
SGSSY
586
SGSSS
591
RSRSL
596
SVSSV
601
SSVSS
606
ATSSS
611
SSAHS
616
VDSED
621
MYADL
626
ASPVS
631
SASSR
636
SPAPA
641
QTRKE
646
KGKSK
651
KEDGV
656
KEEKR
661
KRDSS
666
TQPPK
671
SAKPP
676
AGGKS
681
SQQPS
686
TPQQA
691
PPGQP
696
QQGTF
701
VAHKE
706
IKLTL
711
LNKAA
716
DKGSR
721
KRYEP
726
SDKDR
731
QSPPP
736
AKRPN
741
TSPDR
746
GSRDR
751
KSGGR
756
LGSPK
761
PERQR
766
GQNSK
771
APAAP
776
ADRKR
781
QLSPQ
786
SKSSS
791
KVTSV
796
PGKAS
801
DPGAA
806
STKSG
811
KASTL
816
SRREE
821
LLKQL
826
KAVED
831
AIARK
836
RAKIP
841
GKA
846
Mutation Information
DNA mutation:
None
Peptide Range:
363 ~ 387
Mut AA position:
375 (13 in Wild Type peptide)
Alignment
Wild Type:
"REFDKENEVFRDWNSRIPRDVRDTV
||||||||||||.||||||||||||
Mutant:
REFDKENEVFRDLNSRIPRDVRDTV"
Clin Cancer Res, 2017
Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 ExpressionGene Name (from Reference) ZC3H18
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
ELISPOT assay