Immunogenicity 113
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
PAPPA2
Transcript ID
uc001gkz.3
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (1791 aa)
MMCLK
1
ILRIS
6
LAILA
11
GWALC
16
SANSE
21
LGWTR
26
KKSLV
31
EREHL
36
NQVLL
41
EGERC
46
WLGAK
51
VRRPR
56
ASPQH
61
HLFGV
66
YPSRA
71
GNYLR
76
PYPVG
81
EQEIH
86
HTGRS
91
KPDTE
96
GNAVS
101
LVPPD
106
LTENP
111
AGLRG
116
AVEEP
121
AAPWV
126
GDSPI
131
GQSEL
136
LGDDD
141
AYLGN
146
QRSKE
151
SLGEA
156
GIQKG
161
SAMAA
166
TTTTA
171
IFTTL
176
NEPKP
181
ETQRR
186
GWAKS
191
RQRRQ
196
VWKRR
201
AEDGQ
206
GDSGI
211
SSHFQ
216
PWPKH
221
SLKHR
226
VKKSP
231
PEESN
236
QNGGE
241
GSYRE
246
AETFN
251
SQVGL
256
PILYF
261
SGRRE
266
RLLLR
271
PEVLA
276
EIPRE
281
AFTVE
286
AWVKP
291
EGGQN
296
NPAII
301
AGVFD
306
NCSHT
311
VSDKG
316
WALGI
321
RSGKD
326
KGKRD
331
ARFFF
336
SLCTD
341
RVKKA
346
TILIS
351
HSRYQ
356
PGTWT
361
HVAAT
366
YDGRH
371
MALYV
376
DGTQV
381
ASSLD
386
QSGPL
391
NSPFM
396
ASCRS
401
LLLGG
406
DSSED
411
GHYFR
416
GHLGT
421
LVFWS
426
TALPQ
431
SHFQH
436
SSQHS
441
SGEEE
446
ATDLV
451
LTASF
456
EPVNT
461
EWVPF
466
RDEKY
471
PRLEV
476
LQGFE
481
PEPEI
486
LSPLQ
491
PPLCG
496
QTVCD
501
NVELI
506
SQYNG
511
YWPLR
516
GEKVI
521
RYQVV
526
NICDD
531
EGLNP
536
IVSEE
541
QIRLQ
546
HEALN
551
EAFSR
556
YNISW
561
QLSVH
566
QVHNS
571
TLRHR
576
VVLVN
581
CEPSK
586
IGNDH
591
CDPEC
596
EHPLT
601
GYDGG
606
DCRLQ
611
GRCYS
616
WNRRD
621
GLCHV
626
ECNNM
631
LNDFD
636
DGDCC
641
DPQVA
646
DVRKT
651
CFDPD
656
SPKRA
661
YMSVK
666
ELKEA
671
LQLNS
676
THFLN
681
IYFAS
686
SVRED
691
LAGAA
696
TWPWD
701
KDAVT
706
HLGGI
711
VLSPA
716
YYGMP
721
GHTDT
726
MIHEV
731
GHVLG
736
LYHVF
741
KGVSE
746
RESCN
751
DPCKE
756
TVPSM
761
ETGDL
766
CADTA
771
PTPKS
776
ELCRE
781
PEPTS
786
DTCGF
791
TRFPG
796
APFTN
801
YMSYT
806
DDNCT
811
DNFTP
816
NQVAR
821
MHCYL
826
DLVYQ
831
QWTES
836
RKPTP
841
IPIPP
846
MVIGQ
851
TNKSL
856
TIHWL
861
PPISG
866
VVYDR
871
ASGSL
876
CGACT
881
EDGTF
886
RQYVH
891
TASSR
896
RVCDS
901
SGYWT
906
PEEAV
911
GPPDV
916
DQPCE
921
PSLQA
926
WSPEV
931
HLYHM
936
NMTVP
941
CPTEG
946
CSLEL
951
LFQHP
956
VQADT
961
LTLWV
966
TSFFM
971
ESSQV
976
LFDTE
981
ILLEN
986
KESVH
991
LGPLD
996
TFCDI
1001
PLTIK
1006
LHVDG
1011
KVSGV
1016
KVYTF
1021
DERIE
1026
IDAAL
1031
LTSQP
1036
HSPLC
1041
SGCRP
1046
VRYQV
1051
LRDPP
1056
FASGL
1061
PVVVT
1066
HSHRK
1071
FTDVE
1076
VTPGQ
1081
MYQYQ
1086
VLAEA
1091
GGELG
1096
EASPP
1101
LNHIH
1106
GAPYC
1111
GDGKV
1116
SERLG
1121
EECDD
1126
GDLVS
1131
GDGCS
1136
KVCEL
1141
EEGFN
1146
CVGEP
1151
SLCYM
1156
YEGDG
1161
ICEPF
1166
ERKTS
1171
IVDCG
1176
IYTPK
1181
GYLDQ
1186
WATRA
1191
YSSHE
1196
DKKKC
1201
PVSLV
1206
TGEPH
1211
SLICT
1216
SYHPD
1221
LPNHR
1226
PLTGW
1231
FPCVA
1236
SENET
1241
QDDRS
1246
EQPEG
1251
SLKKE
1256
DEVWL
1261
KVCFN
1266
RPGEA
1271
RAIFI
1276
FLTTD
1281
GLVPG
1286
EHQQP
1291
TVTLY
1296
LTDVR
1301
GSNHS
1306
LGTYG
1311
LSCQH
1316
NPLII
1321
NVTHH
1326
QNVLF
1331
HHTTS
1336
VLLNF
1341
SSPRV
1346
GISAV
1351
ALRTS
1356
SRIGL
1361
SAPSN
1366
CISED
1371
EGQNH
1376
QGQSC
1381
IHRPC
1386
GKQDS
1391
CPSLL
1396
LDHAD
1401
VVNCT
1406
SIGPG
1411
LMKCA
1416
ITCQR
1421
GFALQ
1426
ASSGQ
1431
YIRPM
1436
QKEIL
1441
LTCSS
1446
GHWDQ
1451
NVSCL
1456
PVDCG
1461
VPDPS
1466
LVNYA
1471
NFSCS
1476
EGTKF
1481
LKRCS
1486
ISCVP
1491
PAKLQ
1496
GLSPW
1501
LTCLE
1506
DGLWS
1511
LPEVY
1516
CKLEC
1521
DAPPI
1526
ILNAN
1531
LLLPH
1536
CLQDN
1541
HDVGT
1546
ICKYE
1551
CKPGY
1556
YVAES
1561
AEGKV
1566
RNKLL
1571
KIQCL
1576
EGGIW
1581
EQGSC
1586
IPVVC
1591
EPPPP
1596
VFEGM
1601
YECTN
1606
GFSLD
1611
SQCVL
1616
NCNQE
1621
REKLP
1626
ILCTK
1631
EGLWT
1636
QEFKL
1641
CENLQ
1646
GECPP
1651
PPSEL
1656
NSVEY
1661
KCEQG
1666
YGIGA
1671
VCSPL
1676
CVIPP
1681
SDPVM
1686
LPENI
1691
TADTL
1696
EHWME
1701
PVKVQ
1706
SIVCT
1711
GRRQW
1716
HPDPV
1721
LVHCI
1726
QSCEP
1731
FQADG
1736
WCDTI
1741
NNRAY
1746
CHYDG
1751
GDCCS
1756
STLSS
1761
KKVIP
1766
FAADC
1771
DLDEC
1776
TCRDP
1781
KAEEN
1786
Q
1791
Mutation Information
DNA mutation:
c.A4837G
Peptide Range:
1601 ~ 1625
Mut AA position:
1613 (13 in Wild Type peptide)
Alignment
Wild Type:
"VFEGMYECTNGFSLDSQCVLNCNQE
||||||||||||.||||||||||||
Mutant:
VFEGMYECTNGFGLDSQCVLNCNQE"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) PAPPA2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
VFEGMYECTNGFGLDSQCVLNCNQE
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT