Immunogenicity 11314
Sample ID
3775
Response
Negative
Tumor Type
Cervical Carcinoma(HPV+)
Gene Symbol
FREM2
Transcript ID
uc001uwv.3
HLA INFO
B*35:01
TCR INFO
No TCR info found!
Full length protein sequence (3169 aa)
MHSAG
1
TPGLS
6
SRRTG
11
NSTSF
16
QPGPP
21
PPPRL
26
LLLLL
31
LLLSL
36
VSRVP
41
AQPAA
46
FGRAL
51
LSPGL
56
AGAAG
61
VPAEE
66
AIVLA
71
NRGLR
76
VPFGR
81
EVWLD
86
PLHDL
91
VLQVQ
96
PGDRC
101
AVSVL
106
DNDAL
111
AQRPG
116
RLSPK
121
RFPCD
126
FGPGE
131
VRYSH
136
LGARS
141
PSRDR
146
VRLQL
151
RYDAP
156
GGAVV
161
LPLVL
166
EVEVV
171
FTQLE
176
VVTRN
181
LPLVV
186
EELLG
191
TSNAL
196
DARSL
201
EFAFQ
206
PETEE
211
CRVGI
216
LSGLG
221
ALPRY
226
GELLH
231
YPQVP
236
GGARE
241
GGAPE
246
TLLMD
251
CKAFQ
256
ELGVR
261
YRHTA
266
ASRSP
271
NRDWI
276
PMVVE
281
LRSRG
286
APVGS
291
PALKR
296
EHFQV
301
LVRIR
306
GGAEN
311
TAPKP
316
SFVAM
321
MMMEV
326
DQFVL
331
TALTP
336
DMLAA
341
EDAES
346
PSDLL
351
IFNLT
356
SPFQP
361
GQGYL
366
VSTDD
371
RSLPL
376
SSFTQ
381
RDLRL
386
LKIAY
391
QPPSE
396
DSDQE
401
RLFEL
406
ELEVV
411
DLEGA
416
ASDPF
421
AFMVV
426
VKPMN
431
TMAPV
436
VTRNT
441
GLILY
446
EGQSR
451
PLTGP
456
AGSGP
461
QNLVI
466
SDEDD
471
LEAVR
476
LEVVA
481
GLRHG
486
HLVIL
491
GASSG
496
SSAPK
501
SFTVA
506
ELAAG
511
QVVYQ
516
HDDRD
521
GSLSD
526
NLVLR
531
MVDGG
536
GRHQV
541
QFLFP
546
ITLVP
551
VDDQP
556
PVLNA
561
NTGLT
566
LAEGE
571
TVPIL
576
PLSLS
581
ATDMD
586
SDDSL
591
LLFVL
596
ESPFL
601
TTGHL
606
LLRQT
611
HPPHE
616
KQELL
621
RGLWR
626
KEGAF
631
YERTV
636
TEWQQ
641
QDITE
646
GRLFY
651
RHSGP
656
HSPGP
661
VTDQF
666
TFRVQ
671
DNHDP
676
PNQSG
681
LQRFV
686
IRIHP
691
VDRLP
696
PELGS
701
GCPLR
706
MVVQE
711
SQLTP
716
LRKKW
721
LRYTD
726
LDTDD
731
RELRY
736
TVTQS
741
PTDTD
746
ENHLP
751
APLGT
756
LVLTD
761
NPSVV
766
VTHFT
771
QAQIN
776
HHKIA
781
YRPPG
786
QELGV
791
ATRVA
796
QFQFQ
801
VEDRA
806
GNVAP
811
GTFTL
816
YLHPV
821
DNQPP
826
EILNT
831
GFTIQ
836
EKGHH
841
ILSET
846
ELHVN
851
DVDTD
856
VAHIS
861
FTLTQ
866
APKHG
871
HMRVS
876
GQILH
881
VGGLF
886
HLEDI
891
KQGRV
896
SYAHN
901
GDKSL
906
TDSCS
911
LEVSD
916
RHHVV
921
PITLR
926
VNVRP
931
VDDEV
936
PILSH
941
PTGTL
946
ESYLD
951
VLENG
956
ATEIT
961
ANVIK
966
GTNEE
971
TDDLM
976
LTFLL
981
EDPPL
986
YGEIL
991
VNGIP
996
AEQFT
1001
QRDIL
1006
EGSVV
1011
YTHTS
1016
GEIGL
1021
LPKAD
1026
SFNLS
1031
LSDMS
1036
QEWRI
1041
GGNTI
1046
QGVTI
1051
WVTIL
1056
PVDSQ
1061
APEIF
1066
VGEQL
1071
IVMEG
1076
DKSVI
1081
TSVHI
1086
SAEDV
1091
DSLND
1096
DILCT
1101
IVIQP
1106
TSGYV
1111
ENISP
1116
APGSE
1121
KSRAG
1126
IAISA
1131
FNLKD
1136
LRQGH
1141
INYVQ
1146
SVHKG
1151
VEPVE
1156
DRFVF
1161
RCSDG
1166
INFSE
1171
RQFFP
1176
IVIIP
1181
TNDEQ
1186
PEMFM
1191
REFMV
1196
MEGMS
1201
LVIDT
1206
PILNA
1211
ADADV
1216
PLDDL
1221
TFTIT
1226
QFPTH
1231
GHIMN
1236
QLING
1241
TVLVE
1246
SFTLD
1251
QIIES
1256
SSIIY
1261
EHDDS
1266
ETQED
1271
SFVIK
1276
LTDGK
1281
HSVEK
1286
TVLII
1291
VIPVD
1296
DETPR
1301
MTINN
1306
GLEIE
1311
IGDTK
1316
IINNK
1321
ILMAT
1326
DLDSE
1331
DKSLV
1336
YIIRY
1341
GPGHG
1346
LLQRR
1351
KPTGA
1356
FENIT
1361
LGMNF
1366
TQDEV
1371
DRNLI
1376
QYVHL
1381
GQEGI
1386
RDLIK
1391
FDVTD
1396
GINPL
1401
IDRYF
1406
YVSIG
1411
SIDIV
1416
FPDVI
1421
SKGVS
1426
LKEGG
1431
KVTLT
1436
TDLLS
1441
TSDLN
1446
SPDEN
1451
LVFTI
1456
TRAPM
1461
RGHLE
1466
CTDQP
1471
GVSIT
1476
SFTQL
1481
QLAGN
1486
KIYYI
1491
HTADD
1496
EVKMD
1501
SFEFQ
1506
VTDGR
1511
NPVFR
1516
TFRIS
1521
ISDVD
1526
NKKPV
1531
VTIHK
1536
LVVSE
1541
SENKL
1546
ITPFE
1551
LTVED
1556
RDTPD
1561
KLLKF
1566
TITQV
1571
PIHGH
1576
LLFNN
1581
TRPVM
1586
VFTKQ
1591
DLNEN
1596
LISYK
1601
HDGTE
1606
SSEDS
1611
FSFTV
1616
TDGTH
1621
TDFYV
1626
FPDTV
1631
FETRR
1636
PQVMK
1641
IQVLA
1646
VDNSV
1651
PQIAV
1656
NKGAS
1661
TLRTL
1666
ATGHL
1671
GFMIT
1676
SKILK
1681
VEDRD
1686
SLHIS
1691
LRFIV
1696
TEAPQ
1701
HGYLL
1706
NLDKG
1711
NHSIT
1716
QFTQA
1721
DIDDM
1726
KICYV
1731
LREGA
1736
NATSD
1741
MFYFA
1746
VEDGG
1751
GNKLT
1756
YQNFR
1761
LNWAW
1766
ISFEK
1771
EYYLV
1776
NEDSK
1781
FLDVV
1786
LKRRG
1791
YLGET
1796
SFISI
1801
GTRDR
1806
TAEKD
1811
KDFKG
1816
KAQKQ
1821
VQFNP
1826
GQTRA
1831
TWRVR
1836
ILSDG
1841
EHEQS
1846
ETFQV
1851
VLSEP
1856
VLAAL
1861
EFPTV
1866
ATVEI
1871
VDPGD
1876
EPTVF
1881
IPQSK
1886
YSVEE
1891
DVGEL
1896
FIPIR
1901
RSGDV
1906
SQELM
1911
VVCYT
1916
QQGTA
1921
TGTVP
1926
TSVLS
1931
YSDYI
1936
SRPED
1941
HTSVV
1946
RFDKD
1951
EREKL
1956
CRIVI
1961
IDDSL
1966
YEEEE
1971
TFHVL
1976
LSMPM
1981
GGRIG
1986
SEFPG
1991
AQVTI
1996
VPDKD
2001
DEPIF
2006
YFGDV
2011
EYSVD
2016
ESAGY
2021
VEVQV
2026
WRTGT
2031
DLSKS
2036
SSVTV
2041
RSRKT
2046
DPPSA
2051
DAGTD
2056
YVGIS
2061
RNLDF
2066
APGVN
2071
MQPVR
2076
VVILD
2081
DLGQP
2086
ALEGI
2091
EKFEL
2096
VLRMP
2101
MNAAL
2106
GEPSK
2111
ATVSI
2116
NDSVS
2121
DLPKM
2126
QFKER
2131
IYTGS
2136
ESDGQ
2141
IVTMI
2146
HRTGD
2151
VQYRS
2156
SVRCY
2161
TRQGS
2166
AQVMM
2171
DFEER
2176
PNTDT
2181
SIITF
2186
LPGET
2191
EKPCI
2196
LELMD
2201
DVLYE
2206
EVEEL
2211
RLVLG
2216
TPQSN
2221
SPFGA
2226
AVGEQ
2231
NETLI
2236
RIRDD
2241
ADKTV
2246
IKFGE
2251
TKFSV
2256
TEPKE
2261
PGESV
2266
VIRIP
2271
VIRQG
2276
DTSKV
2281
SIVRV
2286
HTKDG
2291
SATSG
2296
EDYHP
2301
VSEEI
2306
EFKEG
2311
ETQHV
2316
VEIEV
2321
TFDGV
2326
REMRE
2331
AFTVH
2336
LKPDE
2341
NMIAE
2346
MQLTK
2351
AIVYI
2356
EEMSS
2361
MADVT
2366
FPSVP
2371
QIVSL
2376
LMYDD
2381
TSKAK
2386
ESAEP
2391
MSGYP
2396
VICIT
2401
ACNPK
2406
YSDYD
2411
KTGSI
2416
CASEN
2421
INDTL
2426
TRYRW
2431
LISAP
2436
AGPDG
2441
VTSPM
2446
REVDF
2451
DTFFT
2456
SSKMV
2461
TLDSI
2466
YFQPG
2471
SRVQC
2476
AARAV
2481
NTNGD
2486
EGLEL
2491
MSPIV
2496
TISRE
2501
EGLCQ
2506
PRVPG
2511
VVGAE
2516
PFSAK
2521
LRYTG
2526
PEDAD
2531
YTNLI
2536
KLTVT
2541
MPHID
2546
GMLPV
2551
ISTRE
2556
LSNFE
2561
LTLSP
2566
DGTRV
2571
GNHKC
2576
SNLLD
2581
YTEVK
2586
THYGF
2591
LTDAT
2596
KNPEI
2601
IGETY
2606
PYQYS
2611
LSIRG
2616
STTLR
2621
FYRNL
2626
NLEAC
2631
LWEFV
2636
SYYDM
2641
SELLA
2646
DCGGT
2651
IGTDG
2656
QVLNL
2661
VQSYV
2666
TLRVP
2671
LYVSY
2676
VFHSP
2681
VGVGG
2686
WQHFD
2691
LKSEL
2696
RLTFV
2701
YDTAI
2706
LWNDG
2711
IGSPP
2716
EAELQ
2721
GSLYP
2726
TSMRI
2731
GDEGR
2736
LAVHF
2741
KTEAQ
2746
FHGLF
2751
VLSHP
2756
ASFTS
2761
SVIMS
2766
ADHPG
2771
LTFSL
2776
RLIRS
2781
EPTYN
2786
QPVQQ
2791
WSFVS
2796
DFAVR
2801
DYSGT
2806
YTVKL
2811
VPCTA
2816
PSHQE
2821
YRLPV
2826
TCNPR
2831
EPVTF
2836
DLDIR
2841
FQQVS
2846
DPVAA
2851
EFSLN
2856
TQMYL
2861
LSKKS
2866
LWLSD
2871
GSMGF
2876
GQESD
2881
VAFAE
2886
GDIIY
2891
GRVMV
2896
DPVQN
2901
LGDSF
2906
YCSIE
2911
KVFLC
2916
TGADG
2921
YVPKY
2926
SPMNA
2931
EYGCL
2936
ADSPS
2941
LLYRF
2946
KIVDK
2951
AQPET
2956
QATSF
2961
GNVLF
2966
NAKLA
2971
VDDPE
2976
AILLV
2981
NQPGS
2986
DGFKV
2991
DSTPL
2996
FQVAL
3001
GREWY
3006
IHTIY
3011
TVRSK
3016
DNANR
3021
GIGKR
3026
SVEYH
3031
SLVSQ
3036
GKPQS
3041
TTKSR
3046
KKREI
3051
RSTPS
3056
LAWEI
3061
GAENS
3066
RGTNI
3071
QHIAL
3076
DRTKR
3081
QIPHG
3086
RAPPD
3091
GILPW
3096
ELNSP
3101
SSAVS
3106
LVTVV
3111
GGTTV
3116
GLLTI
3121
CLTVI
3126
AVLMC
3131
RGKES
3136
FRGKD
3141
APKGS
3146
SSSEP
3151
MVPPQ
3156
SHHND
3161
SSEV
3166
Mutation Information
DNA mutation:
None
Peptide Range:
1356 ~ 1380
Mut AA position:
1368 (13 in Wild Type peptide)
Alignment
Wild Type:
"KPTGAFENITLGMNFTQDEVDRNLI
||||||||||||.||||||||||||
Mutant:
KPTGAFENITLGINFTQDEVDRNLI"
Science, 2017
Landscape of immunogenic tumor antigens in successful immunotherapy of virally induced epithelial cancerGene Name (from Reference) FREM2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay