Immunogenicity 1140

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
HS3ST6
Transcript ID
ENST00000293937
HLA INFO
DRB*13:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*13:01
sequence
Full length protein sequence (342 aa)
MAGSG
1
GLGGG
6
AGGGQ
11
GAGAG
16
QGAAL
21
RASRA
26
PMLLV
31
ALVLG
36
AYCLC
41
ALPGR
46
CPPAA
51
RAPAP
56
APAPS
61
EPSSS
66
VHRPG
71
APGLP
76
LASGP
81
GRRRF
86
PQALI
91
VGVKK
96
GGTRA
101
LLEFL
106
RLHPD
111
VRALG
116
SEPHF
121
FDRCY
126
ERGLA
131
WYRSL
136
MPRTL
141
DGQIT
146
MEKTP
151
SYFVT
156
REAPR
161
RIHAM
166
SPDTK
171
LIVVV
176
RNPVT
181
RAISD
186
YAQTL
191
SKTPG
196
LPSFR
201
ALAFR
206
HGLGP
211
VDTAW
216
SAVRI
221
GLYAQ
226
HLDHW
231
LRYFP
236
LSHFL
241
FVSGE
246
RLVSD
251
PAGEV
256
GRVQD
261
FLGLK
266
RVVTD
271
KHFYF
276
NATKG
281
FPCLK
286
KAQGG
291
SRPRC
296
LGKSK
301
GRPHP
306
RVPQA
311
LVRRL
316
QEFYR
321
PFNRR
326
FYQMT
331
GQDFG
336
WG
341
Mutation Information
DNA mutation:
None
Peptide Range:
90 ~ 114
Mut AA position:
102 (13 in Wild Type peptide)
Alignment
Wild Type:
"FPQALIVGVKKGGTRALLEFLRLHP
||||||||||||.||||||||||||
Mutant:
FPQALIVGVKKGSTRALLEFLRLHP"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) HS3ST6

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay