Immunogenicity 11436
Sample ID
2369
Response
Negative
Tumor Type
Melanoma
Gene Symbol
KIF21B
Transcript ID
uc001gvr.2
HLA INFO
A*26:01
TCR INFO
No TCR info found!
Full length protein sequence (1624 aa)
MAGQG
1
DCCVK
6
VAVRI
11
RPQLS
16
KEKIE
21
GCHIC
26
TSVTP
31
GEPQV
36
LLGKD
41
KAFTY
46
DFVFD
51
LDTWQ
56
EQIYS
61
TCVSK
66
LIEGC
71
FEGYN
76
ATVLA
81
YGQTG
86
AGKTY
91
TMGTG
96
FDMAT
101
SEEEQ
106
GIIPR
111
AIAHL
116
FGGIA
121
ERKRR
126
AQEQG
131
VAGPE
136
FKVSA
141
QFLEL
146
YNEEI
151
LDLFD
156
STRDP
161
DTRHR
166
RSNIK
171
IHEDA
176
NGGIY
181
TTGVT
186
SRLIH
191
SQEEL
196
IQCLK
201
QGALS
206
RTTAS
211
TQMNV
216
QSSRS
221
HAIFT
226
IHLCQ
231
MRMCT
236
QPDLV
241
NEAVT
246
GLPDG
251
TPPSS
256
EYETL
261
TAKFH
266
FVDLA
271
GSERL
276
KRTGA
281
TGERA
286
KEGIS
291
INCGL
296
LALGN
301
VISAL
306
GDQSK
311
KVVHV
316
PYRDS
321
KLTRL
326
LQDSL
331
GGNSQ
336
TIMIA
341
CVSPS
346
DRDFM
351
ETLNT
356
LKYAN
361
RARNI
366
KNKVV
371
VNQDK
376
TSQQI
381
SALRA
386
EIARL
391
QMELM
396
EYKAG
401
KRVIG
406
EDGAE
411
GYSDL
416
FRENA
421
MLQKE
426
NGALR
431
LRVKA
436
MQEAI
441
DAINN
446
RVTQL
451
MSQEA
456
NLLLA
461
KAGDG
466
NEAIG
471
ALIQN
476
YIREI
481
EELRT
486
KLLES
491
EAMNE
496
SLRRS
501
LSRAS
506
ARSPY
511
SLGAS
516
PAAPA
521
FGGSP
526
ASSME
531
DASEV
536
IRRAK
541
QDLER
546
LKKKE
551
VRQRR
556
KSPEK
561
EAFKK
566
RAKLQ
571
QENSE
576
ETDEN
581
EAEEE
586
EEERD
591
ESGCE
596
EEEGR
601
EDEDE
606
DSGSE
611
ESLVD
616
SDSDP
621
EEKEV
626
NFQAD
631
LADLT
636
CEIEI
641
KQKLI
646
DELEN
651
SQRRL
656
QTLKH
661
QYEEK
666
LILLQ
671
NKIRD
676
TQLER
681
DRVLQ
686
NLSTM
691
ECYTE
696
EKANK
701
IKADY
706
EKRLR
711
EMNRD
716
LQKLQ
721
AAQKE
726
HARLL
731
KNQSR
736
YEREL
741
KKLQA
746
EVAEM
751
KKAKV
756
ALMKQ
761
MREEQ
766
QRRRL
771
VETKR
776
NREIA
781
QLKKE
786
QRRQE
791
FQIRA
796
LESQK
801
RQQEM
806
VLRRK
811
TQEVS
816
ALRRL
821
AKPMS
826
ERVAG
831
RAGLK
836
PPMLD
841
SGAEV
846
SASTT
851
SSEAE
856
SGARS
861
VSSIV
866
RQWNR
871
KINHF
876
LGDHP
881
APTVN
886
GTRPA
891
RKKFQ
896
KKGAS
901
QSFSK
906
AARLK
911
WQSLE
916
RRIID
921
IVMQR
926
MTIVN
931
LEADM
936
ERLIK
941
KREEL
946
FLLQE
951
ALRRK
956
RERLQ
961
AESPE
966
EEKGL
971
QELAE
976
EIEVL
981
AANID
986
YINDG
991
ITDCQ
996
ATIVQ
1001
LEETK
1006
EELDS
1011
TDTSV
1016
VISSC
1021
SLAEA
1026
RLLLD
1031
NFLKA
1036
SIDKG
1041
LQVAQ
1046
KEAQI
1051
RLLEG
1056
RLRQT
1061
DMAGS
1066
SQNHL
1071
LLDAL
1076
REKAE
1081
AHPEL
1086
QALIY
1091
NVQQE
1096
NGYAS
1101
TDEEI
1106
SEFSE
1111
GSFSQ
1116
SFTMK
1121
GSTSH
1126
DDFKF
1131
KSEPK
1136
LSAQM
1141
KAVSA
1146
ECLGP
1151
PLDIS
1156
TKNIT
1161
KSLAS
1166
LVEIK
1171
EDGVG
1176
FSVRD
1181
PYYRD
1186
RVSRT
1191
VSLPT
1196
RGSTF
1201
PRQSR
1206
ATETS
1211
PLTRR
1216
KSYDR
1221
GQPIR
1226
STDVG
1231
FTPPS
1236
SPPTR
1241
PRNDR
1246
NVFSR
1251
LTSNQ
1256
SQGSA
1261
LDKGI
1266
ISPVG
1271
GAKGA
1276
RTAPL
1281
QCVSM
1286
AEGHT
1291
KPILC
1296
LDATD
1301
ELLFT
1306
GSKDR
1311
SCKMW
1316
NLVTG
1321
QEIAA
1326
LKGHP
1331
NNVVS
1336
IKYCS
1341
HSGLV
1346
FSVST
1351
SYIKV
1356
WDIRD
1361
SAKCI
1366
RTLTS
1371
SGQVI
1376
SGDAC
1381
AATST
1386
RAITS
1391
AQGEH
1396
QINQI
1401
ALSPS
1406
GTMLY
1411
AASGN
1416
AVRIW
1421
ELSRF
1426
QPVGK
1431
LTGHI
1436
GPVMC
1441
LTVTQ
1446
TASQH
1451
DLVVT
1456
GSKDH
1461
YVKMF
1466
ELGEC
1471
VTGTI
1476
GPTHN
1481
FEPPH
1486
YDGIE
1491
CLAIQ
1496
GDILF
1501
SGSRD
1506
NGIKK
1511
WDLDQ
1516
QELIQ
1521
QIPNA
1526
HKDWV
1531
CALAF
1536
IPGRP
1541
MLLSA
1546
CRAGV
1551
IKVWN
1556
VDNFT
1561
PIGEI
1566
KGHDS
1571
PINAI
1576
CTNAK
1581
HIFTA
1586
SSDCR
1591
VKLWN
1596
YVPGL
1601
TPCLP
1606
RRVLA
1611
IKGRA
1616
TTLP
1621
Mutation Information
DNA mutation:
c.3526G>A
Peptide Range:
1173 ~ 1181
Mut AA position:
1176 (4 in Wild Type peptide)
Alignment
Wild Type:
"EIKEDGVGF
|||.|||||
Mutant:
EIKKDGVGF"
Nat Med, 2013
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cellsGene Name (from Reference) KIF21B
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
peptide
T-cell
Source
TILs
APC
Type
None
Assay
IFNg ELISPOT assay