Immunogenicity 11455
Sample ID
2098
Response
Negative
Tumor Type
Melanoma
Gene Symbol
TRPC6
Transcript ID
uc001pgk.4
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (931 aa)
MSQSP
1
AFGPR
6
RGSSP
11
RGAAG
16
AAARR
21
NESQD
26
YLLMD
31
SELGE
36
DGCPQ
41
APLPC
46
YGYYP
51
CFRGS
56
DNRLA
61
HRRQT
66
VLREK
71
GRRLA
76
NRGPA
81
YMFSD
86
RSTSL
91
SIEEE
96
RFLDA
101
AEYGN
106
IPVVR
111
KMLEE
116
CHSLN
121
VNCVD
126
YMGQN
131
ALQLA
136
VANEH
141
LEITE
146
LLLKK
151
ENLSR
156
VGDAL
161
LLAIS
166
KGYVR
171
IVEAI
176
LSHPA
181
FAEGK
186
RLATS
191
PSQSE
196
LQQDD
201
FYAYD
206
EDGTR
211
FSHDV
216
TPIIL
221
AAHCQ
226
EYEIV
231
HTLLR
236
KGARI
241
ERPHD
246
YFCKC
251
NDCNQ
256
KQKHD
261
SFSHS
266
RSRIN
271
AYKGL
276
ASPAY
281
LSLSS
286
EDPVM
291
TALEL
296
SNELA
301
VLANI
306
EKEFK
311
NDYKK
316
LSMQC
321
KDFVV
326
GLLDL
331
CRNTE
336
EVEAI
341
LNGDV
346
ETLQS
351
GDHGR
356
PNLSR
361
LKLAI
366
KYEVK
371
KFVAH
376
PNCQQ
381
QLLSI
386
WYENL
391
SGLRQ
396
QTMAV
401
KFLVV
406
LAVAI
411
GLPFL
416
ALIYW
421
FAPCS
426
KMGKI
431
MRGPF
436
MKFVA
441
HAASF
446
TIFLG
451
LLVMN
456
AADRF
461
EGTKL
466
LPNET
471
STDNA
476
KQLFR
481
MKTSC
486
FSWME
491
MLIIS
496
WVIGM
501
IWAEC
506
KEIWT
511
QGPKE
516
YLFEL
521
WNMLD
526
FGMLA
531
IFAAS
536
FIARF
541
MAFWH
546
ASKAQ
551
SIIDA
556
NDTLK
561
DLTKV
566
TLGDN
571
VKYYN
576
LARIK
581
WDPSD
586
PQIIS
591
EGLYA
596
IAVVL
601
SFSRI
606
AYILP
611
ANESF
616
GPLQI
621
SLGRT
626
VKDIF
631
KFMVI
636
FIMVF
641
VAFMI
646
GMFNL
651
YSYYI
656
GAKQN
661
EAFTT
666
VEESF
671
KTLFW
676
AIFGL
681
SEVKS
686
VVINY
691
NHKFI
696
ENIGY
701
VLYGV
706
YNVTM
711
VIVLL
716
NMLIA
721
MINSS
726
FQEIE
731
DDADV
736
EWKFA
741
RAKLW
746
FSYFE
751
EGRTL
756
PVPFN
761
LVPSP
766
KSLFY
771
LLLKL
776
KKWIS
781
ELFQG
786
HKKGF
791
QEDAE
796
MNKIN
801
EEKKL
806
GILGS
811
HEDLS
816
KLSLD
821
KKQVG
826
HNKQP
831
SIRSS
836
EDFHL
841
NSFNN
846
PPRQY
851
QKIMK
856
RLIKR
861
YVLQA
866
QIDKE
871
SDEVN
876
EGELK
881
EIKQD
886
ISSLR
891
YELLE
896
EKSQN
901
TEDLA
906
ELIRE
911
LGEKL
916
SMEPN
921
QEETN
926
R
931
Mutation Information
DNA mutation:
c.271G>A
Peptide Range:
86 ~ 95
Mut AA position:
91 (6 in Wild Type peptide)
Alignment
Wild Type:
"YMFSDRSTSL
|||||.||||
Mutant:
YMFSDCSTSL"
Nat Med, 2013
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cellsGene Name (from Reference) TRPC6
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
peptide
T-cell
Source
TILs
APC
Type
T2
Assay
IFNg ELISPOT assay