Immunogenicity 11490
Sample ID
2369
Response
Negative
Tumor Type
Melanoma
Gene Symbol
CHRNB4
Transcript ID
uc002bed.1
HLA INFO
A*01:01
TCR INFO
No TCR info found!
Full length protein sequence (498 aa)
MRRAP
1
SLVLF
6
FLVAL
11
CGRGN
16
CRVAN
21
AEEKL
26
MDDLL
31
NKTRY
36
NNLIR
41
PATSS
46
SQLIS
51
IKLQL
56
SLAQL
61
ISVNE
66
REQIM
71
TTNVW
76
LKQEW
81
TDYRL
86
TWNSS
91
RYEGV
96
NILRI
101
PAKRI
106
WLPDI
111
VLYNN
116
ADGTY
121
EVSVY
126
TNLIV
131
RSNGS
136
VLWLP
141
PAIYK
146
SACKI
151
EVKYF
156
PFDQQ
161
NCTLK
166
FRSWT
171
YDHTE
176
IDMVL
181
MTPTA
186
SMDDF
191
TPSGE
196
WDIVA
201
LPGRR
206
TVNPQ
211
DPSYV
216
DVTYD
221
FIIKR
226
KPLFY
231
TINLI
236
IPCVL
241
TTLLA
246
ILVFY
251
LPSDC
256
GEKMT
261
LCISV
266
LLALT
271
FFLLL
276
ISKIV
281
PPTSL
286
DVPLI
291
GKYLM
296
FTMVL
301
VTFSI
306
VTSVC
311
VLNVH
316
HRSPS
321
THTMA
326
PWVKR
331
CFLHK
336
LPTFL
341
FMKRP
346
GPDSS
351
PARAF
356
PPSKS
361
CVTKP
366
EATAT
371
STSPS
376
NFYGN
381
SMYFV
386
NPASA
391
ASKSP
396
AGSTP
401
VAIPR
406
DFWLR
411
SSGRF
416
RQDVQ
421
EALEG
426
VSFIA
431
QHMKN
436
DDEDQ
441
SVVED
446
WKYVA
451
MVVDR
456
LFLWV
461
FMFVC
466
VLGTV
471
GLFLP
476
PLFQT
481
HAASE
486
GPYAA
491
QRD
496
Mutation Information
DNA mutation:
c.673C>T
Peptide Range:
219 ~ 228
Mut AA position:
225 (7 in Wild Type peptide)
Alignment
Wild Type:
"YVDVTYDFII
||||||.|||
Mutant:
YVDVTYNFII"
Nat Med, 2013
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cellsGene Name (from Reference) CHRNB4
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
peptide
T-cell
Source
TILs
APC
Type
HEK293 cells
Assay
IFNg ELISPOT assay